Project Grant 90DPBU0001

This $864,498 Project Grant, awarded by the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) program, supports research at Brigham & Women's Hospital to target neuroinflammation and promote neurological recovery after traumatic spinal cord injury. The research, which will be conducted from August 2025 to July 2028, aims to transform healthcare for military service members, veterans, and the public through innovative biomedical investigations. Brigham...

This Project Grant award from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) provides $4,182,053.00 to The Spaulding Rehabilitation Hospital Corporation to conduct a clinical trial titled "Breathing Low Oxygen to Enhance Spinal Stimulation Training and Functional Recovery for Aging Adults with Chronic SCI: The BO2ST-II Trial." The award period runs from Sep 30, 2024 to Sep 29, 2028. The project will investigate using low-oxygen...

This Project Grant award of $704,313 from the National Institute of Neurological Disorders and Stroke (NINDS) under CFDA 93.853, Extramural Research Programs in the Neurosciences and Neurological Disorders, aims to advance a prognostic and monitoring biomarker of neutrophil-driven secondary brain injury in spontaneous intracerebral hemorrhage. The primary objective is to define and validate a standardized protocol to detect specific neutrophil biomarker levels as a potential prognostic and...

This Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) provides $1,220,472.00 to The General Hospital Corporation (doing business as Massachusetts General Hospital) to conduct research on using B cell therapy to ameliorate pulmonary and neurological sequelae in survivors of acute respiratory distress syndrome (ARDS). The key aims are to study the efficiency of B cell homing to the lungs and brain, identify the immunomodulatory...

This $489,500 Project Grant, awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to characterize the role of the ADB2 protein as a novel complement receptor and its contribution to acute lung injury in sepsis. The research, conducted by The Children's Hospital Corporation (dba Boston Children's Hospital), aims to: 1) Determine the binding profile of ADB2 to complement fragments...

The Department of Defense's (DoD) Military Medical Research and Development program (CFDA 12.420) awarded a $1,009,369 project grant to Brigham & Women's Hospital in Boston, MA. The grant funds a 3-year research project titled "Probing the Role of Ion Channels as Mediators of Post-Traumatic Epileptogenesis: GIRK Channel Modulation as a Roadmap to Therapy." The research aims to: 1) characterize aberrant neuronal activity patterns in the brain following traumatic brain injury...

The Beth Israel Deaconess Medical Center, Inc. (Bidmc) in Boston, Massachusetts was awarded a $1,296,751 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420). The grant, awarded on June 1, 2024, will fund a 2-year research project titled "Electrical Impedance Myography via the Myolex mScan as an ALS Biomarker." The goal of the project is to evaluate a novel diagnostic approach using electrical impedance myography...

This federal Project Grant award, valued at $654,273.00, was provided by the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) program. The grant supports research to develop innovative variable ventilation approaches to reduce ventilator-induced lung injury in patients with acute respiratory distress syndrome (ARDS). The primary awardee is Brigham & Women's Hospital Inc., which is a prominent academic medical center and research institution in Boston,...

The federal Project Grant award of $1,715,075.00 was provided by the Defense Health Agency to Beth Israel Deaconess Medical Center, Inc. (Bidmc) under the Military Medical Research and Development (CFDA 12.420) program. The funding supports research on "The Role of TBI Derived DAMPS in Bacterial Pneumonia" over a period from September 30, 2023 to September 29, 2026. As a major academic medical center and teaching hospital, Bidmc has an extensive portfolio of federal grants and...

The Department of the Army Medical Command awarded a $711,403 project grant to The Children's Hospital Corporation (doing business as Boston Children's Hospital) under the Military Medical Research and Development program (CFDA 12.420). The grant supports a project titled "A Noninvasive Neurotrophic Factor Treatment to Repair the Injured Spinal Cord" with a period of performance from October 1, 2024 to September 30, 2027. This project grant supports advanced biomedical research focused...