Cooperative Agreement 2537986
- This $274,547 Project Grant awarded by the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program aims to develop a novel Aneurysm Sealing Device (ASD) for endovascular treatment of Abdominal Aortic Aneurysms (AAA). The project seeks to create a device that can completely seal the aneurysm sac, reducing the risk of post-procedure complications and the need for repeat interventions. Key objectives include validating the device's adaptability...
- This Project Grant award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $275,000 to Aneurisk, Inc. to develop and validate machine learning models for risk classification, growth projection, and wall stress prediction for abdominal aortic aneurysms (AAA). The project aims to create an artificial intelligence-based clinical decision support tool that enables clinicians to improve the treatment of patients with...
- This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Phase I Small Business Innovation Research (SBIR) Project Grant award of $275,000 to Astria Biosciences, Inc. seeks to develop the first simple, whole blood-based diagnostic test to detect the presence and monitor the progression of cerebral aneurysms (CAs). The project aims to generate a robust dataset of CA patient blood samples, with a focus on increasing representation from underserved...
- The National Institute of Neurological Disorders and Stroke awarded $435,979 to Aneuvas Technologies Inc. on September 4, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to develop a novel biocompatible polymer coating for intracranial aneurysm treatment devices. The project will develop and optimize a polymeric coating (PPODA-QT) applied to nitinol flow diverters for endovascular aneurysm treatment. Current metal-based...
- This Project Grant award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program provides $304,906 to Seabird Lifesciences LLC for the development of a novel bioprinting approach to create vascular grafts. The project aims to produce a next-generation vascular graft that improves outcomes for patients undergoing vascular surgeries by enhancing tissue integration, improving long-term performance, and reducing the need for repeat...
- The National Science Foundation awarded Rowan University a $100,000 Project Grant under the Technology, Innovation, and Partnerships program to develop an automatic aortic aneurysm screening software platform using deep learning models. The platform aims to improve the speed and efficiency of computed tomography scan readings, 3D image reconstruction, and aortic aneurysm screening, which are currently done manually. The software will use adaptive image processing and ensemble-based object...
- The National Science Foundation (NSF) awarded a 5-year, $574,881 CAREER grant to The Washington University's Office of Sponsored Research Services Division to investigate the biomechanical consequences of localized defects in the aortic wall. The research aims to better understand the factors that contribute to aortic rupture using innovative mechanobiological, microstructural, and mechanical testing approaches. Specific objectives include a comprehensive biomechanical assessment of aortic...
- This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Cooperative Agreement award to Reselute, Inc. provides $998,921 to develop a novel implantable orthopedic medical device and procedure to reduce recovery duration and infection risks associated with severe traumatic fractures of the long bones. The project aims to advance a 3D-printed, antibiotic-releasing intramedullary nail to improve upon current standard-of-care implants that are prone to...
- The National Institute of Neurological Disorders and Stroke awarded Patchclamp Medtech, Inc. $1,524,947 on July 27, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to develop a novel medical device for sealing dural perforations in minimally invasive spinal and cranial surgery. Patchclamp Medtech will advance a Phase II prototype of an applicator system that delivers and secures a bioabsorbable graft-clasp assembly directly at...
- This Project Grant award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $274,811 to Anova Biomedical, Inc. to develop 3D printed personalized vascular grafts using novel elastomeric resins. The key objectives are to: 1) develop and characterize the novel 3D printing resin for producing personalized, elastic, and bioresorbable vascular grafts; 2) demonstrate the ability to 3D print vascular prosthetics using patient CT...
The National Science Foundation awarded Life Seal Vascular Inc. a $1.25 million cooperative agreement on August 1, 2026, to advance design and testing of the CygNum aneurysm sac management device for endovascular repair of abdominal aortic aneurysms. The recipient will optimize the device's delivery system, verify long-term biocompatibility, and demonstrate reliable performance in laboratory and preclinical models. The technical approach combines a compressible implant with precise endovascular deployment to achieve complete aneurysm sealing and reduce complication risk. Work will generate preclinical evidence of safety and effectiveness to support future clinical evaluation and address a treatment gap for patients with abdominal aortic aneurysms while establishing a platform potentially applicable to related vascular conditions. The award is funded under NSF Technology, Innovation, and Partnerships (CFDA 47.084) and carries a period of performance from August 1, 2026, through July 31, 2028. Performance location is Lake Forest, California. No sub-recipients are planned for this award.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.3m | 7/17/26 |