Cooperative Agreement 2524897
- The National Science Foundation awarded a $275,000 Project Grant to Oraliva, Inc. under the Technology, Innovation, and Partnerships program to develop a portable, programmable single cell cytology platform for the early detection of epithelial cancers. The platform will combine microfluidics and artificial intelligence to classify potentially cancerous tissue in near real-time through multiparameter single-cell analysis and automated evaluation. The objectives are to link different clinical...
- This National Science Foundation (NSF) Project Grant award for $305,000 to Innotech Precision Medicine, Inc. aims to develop and validate a portable diagnostic system that detects cancer markers for both risk and progression in saliva. The project will focus on creating a fully integrated microfluidic device that combines multiple types of biomarker detection into one enclosed cartridge. Key technical challenges to be addressed include improving sample handling consistency, ensuring even reagent...
- The National Cancer Institute (NCI) awarded Oraliva, Inc. a $400,000 Project Grant under the Cancer Detection and Diagnosis Research program (CFDA 93.394) to develop a novel, low-cost, and fully integrated point-of-care (POC) gynecological screening test. The grant, awarded on September 1, 2025, with a completion date of August 31, 2026, will enable Oraliva to leverage its proprietary AI-linked cytomics-on-a-chip technology (ONC-INCYT) to create a rapid, POC diagnostic tool that can accurately...
- This Cooperative Agreement award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program provides $1,213,619 to Encapsulate Inc., a small disadvantaged business, to develop a precision oncology platform that integrates microfluidics, biochips, bioreactors, and 3D tumor models to predict patient-specific cancer drug responses. The project aims to create a rapid and precise method for predicting the effectiveness of various cancer...
- The National Science Foundation (NSF) awarded a $1,250,000 Cooperative Agreement under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program to Nexgen Cancer Detection LLC. The funding will be used to improve and validate a method for diagnosing cancer earlier through a simple blood draw. The project aims to enrich cancer DNA from blood samples to enable highly sensitive and accurate cancer detection, which could lead to earlier cancer diagnosis and treatment, improved patient...
- This $274,594 Project Grant award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program supports research and development of an innovative technology for cancer diagnosis and treatment. The project aims to improve molecular profiling and clinical laboratory testing of cancer samples by optimizing microdissection techniques. The research will focus on modeling and optimizing the opto-thermal-mechanical interactions involved in microdissection to...
- The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $1,414,853 Project Grant under the Oral Diseases and Disorders Research program (CFDA 93.121) to Innotech Precision Medicine, Inc., a woman-owned small business, to develop RECOGNIZE-OPSCC. This saliva-based, point-of-care diagnostic test aims to provide rapid, non-invasive, and accurate detection of oropharyngeal squamous cell carcinoma (OPSCC). The project integrates an AI-enabled, ultraportable device with an...
- The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $1,178,476 Project Grant under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121) to Oraliva, Inc., a technology company in Durham, North Carolina. The purpose of this 2-year project, with a completion date of March 31, 2027, is to develop an AI-linked cytomics-on-a-chip technology to enable near real-time identification and management of oral lichenoid lesions in primary care settings. This...
- This Project Grant from the National Science Foundation's Technology, Innovation, and Partnerships program (CFDA 47.084) provides $275,000 to Dcan Biosciences LLC to develop an advanced microfluidic system for cancer diagnosis and monitoring. The system aims to isolate and assess circulating tumor cells (CTCs) and CTC clusters (CTCCs) from patient blood samples to enable highly sensitive and accurate liquid biopsies. Key objectives include designing a hybrid microfluidic device for...
- This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Cerflux Inc. aims to develop a personalized cancer treatment screening platform. The project will establish guidelines for handling solid tumor biopsy samples, generate 3D bioprinted tumor models for validation, and demonstrate the platform's ability to match patients with the most effective cancer treatments before treatment begins. This innovative approach has the...
This National Science Foundation (NSF) Cooperative Agreement award of $1,244,392 to Oraliva, Inc. under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program will fund the development of a portable single-cell cytology and predictive analysis platform for the early detection of epithelial cancers. The project aims to create an accurate and efficient, AI-linked point-of-care cancer diagnostic technology that can enable early-stage detection, ultimately reducing the economic burden of late-stage cancer diagnosis and treatment. Oraliva, Inc. plans to leverage this funding to advance their microfluidics-based cytomics platform, with the goal of commercializing an innovative diagnostic solution targeting markets such as dentistry, gastroenterology, and gynecology. The project builds upon Oraliva's existing federal grant awards and academic/industry partnerships, indicating their progress in translating fundamental research into practical, market-ready technologies.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.2m | 8/15/25 |