Akttyva Therapeutics, Inc. received a $255,487 Project Grant award from the National Science Foundation Division of Industrial Innovation under the Engineering (47.041) federal grant program. The award period runs from December 1, 2021 through November 30, 2022 to support SBIR Phase I research titled "AI-Assisted Identification of Small Molecules for Targeted Repair of Vascular Barrier Dysfunctions." The funding will allow Akttyva Therapeutics to utilize artificial intelligence...
This $274,797 National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award to Deepseq.ai LLC supports the development of an AI-driven platform to accelerate the identification of highly developable single-domain antibodies for drug discovery. The proposed work aims to create a multimodal AI model capable of rapidly screening large libraries to generate lead molecules with favorable binding affinity, stability, and manufacturability. This project...
This $1,000,000 Cooperative Agreement, awarded by the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084), supports the lead optimization of a novel, broad-spectrum antiviral and immunomodulatory agent to combat coronaviruses, including SARS-CoV-2. The project, conducted by Akanocure Pharmaceuticals Inc., aims to develop an orally administered drug candidate that can suppress viral replication and restore immune system homeostasis,...
This $1,000,000 Cooperative Agreement award from the National Science Foundation's (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program aims to accelerate R&D in the pharmaceutical industry through the development of streamlined machine learning algorithms for small data applications in advanced manufacturing. The project, awarded to Sunthetics Inc., seeks to save time and resources by up to 95% in lead optimization and route scouting during pre-clinical drug development by...
This STTR Phase I award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program provides $264,736 to Duet Biosystems, Inc. to develop an AI-enabled toolkit for optimizing the discovery and use of combination drug therapies. The project aims to leverage improvements in quantitative understanding of drug-drug synergy to overcome challenges associated with combination drug research and development. The research plan consists of an experimental track...
This National Science Foundation (NSF) Cooperative Agreement award under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program provides $1,000,000.00 in funding to Nostopharma LLC, a woman-owned small disadvantaged business, to develop an innovative sustained-release, biodegradable drug delivery platform using anti-inflammatory nanoparticles and Hedgehog pathway antagonists. The goal is to create a localized, targeted medication delivery system to address unmet medical needs for...
This $228,697 National Science Foundation award under the Engineering program (CFDA 47.041) will support the development of an optical biosensor technology to facilitate drug screening and validation efforts. Auctus Biologics, Inc. will utilize a proprietary temperature, pH, and chemically stable protein composed of two fragments that bind with antibody-like affinity and specificity. Over the one-year period ending January 2023, the company will establish the technology's suitability for...
This National Science Foundation (NSF) Cooperative Agreement award under the NSF Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $1,248,531 to Inaedis, Inc. from June 1, 2025 to May 31, 2027 to develop a rapid room-temperature aerosol dehydration platform technology for stabilizing biopharmaceutical formulations. The project aims to address critical challenges in biopharmaceutical manufacturing by creating a scalable system capable of producing stable, bioactive...
This Small Business Innovation Research (SBIR) Phase II Cooperative Agreement, awarded by the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084), aims to develop a novel rapid antibiotic susceptibility testing (AST) platform. The $991,832 award will enable Astek Diagnostics Inc., a minority-owned for-profit company, to adapt their previously developed urine cartridge for use with cerebrospinal fluid and wound effluent specimen...
Altigg Therapeutics, Inc. was awarded a $255,595 Small Business Technology Transfer (STTR) Phase I Project Grant from the National Science Foundation's Engineering program (CFDA 47.041) for the period of April 1, 2021 through March 31, 2022. Under this award, Altigg Therapeutics will develop a platform for the rapid discovery of human antibodies as therapeutics for infectious diseases such as COVID-19. The NSF Engineering program seeks to improve quality of life and economic strength through...