This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Cooperative Agreement award of $1,000,000 to Theromics Inc., a minority-owned small disadvantaged business, aims to develop a novel protein-based gel to improve the effectiveness and safety of thermal tumor ablation procedures.
The project will involve creating a computational model to predict the thermal behavior of the gel, conducting preclinical studies to quantify temperatures, ablation zone size, and thermal energy deposition, assessing the gel's effects during tissue ablation using in vivo porcine lung models, and completing an in vivo chronic safety study. The goal is to generate the necessary preclinical evidence to initiate first-in-human studies for this technology, which has broad applicability to various thermal ablation procedures with a potential market in the hundreds of millions to billions of dollars worldwide.
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