Purchase Order 75N95023P00575
- Not listed
- This is a $13,300 firm fixed-price purchase order awarded by the National Center for Advancing Translational Sciences (NCATS) to Curia Global Inc., doing business as Amri, a leading global contract development and manufacturing organization (CDMO). The contract is for X-ray crystallography studies of ALDH1A2 in complex with a small molecule inhibitor, as part of NCATS' drug discovery and development efforts. No set-aside designation was used. Curia has extensive experience supporting various...
- This federal contract award is for "CHEMISTRY, MANUFACTURING, AND CONTROLS (CMC) DEVELOPMENT OF NCGC00413972 FOR PRECLINICAL SAFETY EVALUATION AND CLINICAL TRIAL" and was issued to Curia Global Inc., doing business as Amri. The contract, valued at $907,791.77, is a delivery order under the "CRO Support for NCATS Drug Substance Development and Manufacture" indefinite-delivery/indefinite-quantity (IDIQ) contract vehicle. The National Center for Advancing Translational...
- Curia Global Inc., doing business as Amri, has been awarded an $11,250 firm fixed price purchase order by the Department of Health and Human Services' National Institutes of Health National Center for Advancing Translational Sciences to provide purification services for McHenry-CNA35 (4L). As a leading global contract development and manufacturing organization, Amri will utilize its expertise in medicinal chemistry, chemical development, analytical testing, formulation development, and cGMP...
- This $142,500 firm-fixed price purchase order was awarded by the Department of Health and Human Services' National Institutes of Health (NIH) National Institute on Aging to Curia Global Inc., doing business as Amri, a global contract development and manufacturing organization (CDMO). The contract is for sequencing services to identify molecules that bind the KIAA0203 protein, in support of the NIH's preclinical drug discovery efforts. No set-aside designation was used. Curia has provided...
- This is a cost-plus-fixed-fee delivery order contract awarded by the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH), to Curia Global Inc. (doing business as Amri) for $815,714.07. The contract is for medicinal chemistry services to support the "ALDRICH (UNIV. OF FLORIDA) - EXPLORATORY CHEMISTRY-ADMET ONLY - MCSP" project, which is part of NINDS's Medicinal Chemistry Support Program for therapeutic development. Curia, a...
- This federal contract award to Curia Global Inc., doing business as Amri, is for the development of the drug substance (R)-VK4-116 dihydrochloride salt. The $1,804,267.88 cost-plus-fixed-fee contract was awarded by the National Center for Advancing Translational Sciences (NCATS), a civilian agency under the Department of Health and Human Services. This contract is a delivery order under the NCATS' larger "CRO Support for NCATS Drug Substance Development and Manufacture"...
- This is a firm fixed-price purchase order awarded by the National Institute on Drug Abuse (NIDA), on behalf of the National Institute of Neurological Disorders and Stroke (NINDS), to Curia Global Inc. (doing business as Amri) for the non-GMP synthesis of up to 100 compounds in 2-10 milligram quantities. The purpose is to identify molecules that bind the KIAA0203 protein, which could potentially lead to the development of a new Alzheimer's drug. The contract has a period of performance from...
- This federal contract task order was awarded by the U.S. Department of Health and Human Services' National Institutes of Health (NIH) National Institute on Aging to Curia Global Inc., doing business as Amri, a leading global contract development and manufacturing organization (CDMO). The $1,376,049.53 cost-plus-fixed-fee task order, awarded on August 15, 2018, supports the Medicinal Chemistry Support Program for Therapeutic Development, providing chemistry, manufacturing, and controls...
- This is a delivery order contract awarded by the National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS) to Curia Global Inc., doing business as Amri, for the Medicinal Chemistry Support Program for Therapeutic Development. The contract, with a potential value of $4,042,434.33, provides chemistry, manufacturing, and controls development; exploratory chemistry; hit-to-lead chemistry; absorption/distribution/metabolism/excretion testing; process...
- The Department of Health and Human Services National Institutes of Health National Institute of Neurological Disorders and Stroke awarded a $1.5 million delivery order contract to Curia Global Inc., doing business as Amri, for TSUKAMOTO (JOHNS HOPKINS UNIVERSITY) MCSP - LEAD OPTIMIZATION CHEMISTRY. The prime contractor, Amri, will perform lead optimization chemistry services in Albany, New York for the agency from September 2023 through March 2025. The contract uses a cost plus fixed fee pricing...
This purchase order contract was awarded by the National Center for Advancing Translational Sciences (NCATS), part of the National Institutes of Health (NIH), to Curia Global Inc. (doing business as Amri) for $79,400. The contract is for X-ray crystallography studies of ALDH1A2 to crystallize two novel small molecules within the enzyme to assist with structure-based drug design as part of an ongoing medicinal chemistry campaign. Specifically, the contractor will perform X-ray crystallography of ALDH1A2, crystallize the target small molecules, and provide assistance in structure-based design over a one-year period of performance. The place of performance is in Stuyvesant Plaza, New York. No subcontractors or set-asides are indicated. NCATS' mission involves facilitating translation of basic scientific discoveries into new and better patient treatments, so this contract supports those efforts through structural analysis of potential drug candidates.
Name | Description | Solicitation Number | FederalAgency | Type | PostedDate |
|---|---|---|---|---|---|
X-Ray Crystallography Studies of ALDH1A2 | 75N95023Q00617 | Department of Health and Human Services National Institutes of Health National Institute on Drug Abuse | Solicitation 1/1 | 8/10/23, 7:46 AM |
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | Not listed | $79.4k | 8/24/23 |