Molecular Devices FLIPR Tetra High-Throughput Cellular Screening Systems with attachments and supporting reagents, brand name or equal
This is a Small Business Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding: (1) the availability and capability of qualified small business sources; (2) whether they are small businesses; HUBZone small businesses; service-disabled, veteran-owned small businesses; 8(a) small businesses; veteran-owned small businesses; woman-owned small businesses; or small disadvantaged businesses; and (3) their size classification relative to the North American Industry Classification System (NAICS) code for the proposed acquisition. Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. An organization that is not considered a small business under the applicable NAICS code should not submit a response to this notice. Please note that to qualify as an eligible small business for purposes of a small business set-aside, at least 50% of the cost of contract performance incurred for personnel must be expended for employees of the small business awardee (see FAR 52.219-14 Limitations on Subcontracting). Purpose and Objectives The National Institutes of Health (NIH) is the nation's leading medical research agency and the primary Federal agency whose mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability, conducting, supporting and making medical discoveries that improve people's health and save lives. The National Center for Advancing Translational Sciences (NCATS) is a translational science center that prides itself on its tremendously productive pipeline and is innovative in several ways. NCATS brings together a diverse range of scientists, including medicinal chemists, biologists, toxicologists, and engineers, in to ultimately translate basic science into real products and services that help improve people's lives. NCATS seeks high-toughput cellular screening systems to aid in the fight against opioid addiction and enhance research on pain management. These systems will add to NCATS' existing robotic system and increase NCATS' ability to perform time-sensitive assays and address key technological needs for projects that have strong implications on the pain and opioid addiction fields of research. Project Requirements NCATS seeks to purchase two (2) Molecular Devices FLIPR Tetra High-Toughput Cellular Screening Systems, or brand-name equal systems. The FLIPR Tetra High-Toughput Cellular Screening System provides an automated solution for identifying early leads in the drug discovery process and for evaluating drug efficacy and toxicity. With simultaneous pipette and read function, the system supports fast kinetic cellular assays. It can be quickly configured based on library size, detection mode, screening format, assay and target. It is a fully integrated solution with a seamless transition from assay development to lead optimization. The FLIPR Tetra systems are commercially available and are customized with options to fit the specific laboratory needs. Brand name or equal multimodal high-toughput cellular screening systems must have the following salient characteristics: Intensified CCD camera capable of both standard fluorescence and aequorin luminescence detection to enable membrane potential assays/detection User-configurable 384-, and 1536-well pipettors/pin tools User-exchangeable cell suspension option Intuitive, user-friendly software interface Internal plate handler for accelerated toughput Easy Integration into the Kalypsys Robotic Platform The requirements also include field installation of the systems and on-site training for NCATS staff. Anticipated Period of Performance Delivery of the systems is to occur within ten (10) weeks after receipt of order, with installation and on-site training occurring shortly thereafter. Required Information All capability statements must provide the following: (1) DUNS number; (2) organization name; (3) organization address; (4) point of contact; (5) point of contact title, address, telephone, and email address; and (6) size and type of business (e.g., 8(a), HUBZone, etc.) pursuant the applicable NAICS code. Submission Instructions and Due Date Written capability statements must be SUBMITTED NO LATER THAN 12:00PM EDT FRIDAY, AUGUST 10, 2018 to the below Contracting Office Address, Attn: Kimberly Espinosa. Electronic capability statements will be accepted by the primary point of contact listed below. Disclaimer and Important Notes This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a pre-solicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation. Confidentiality No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s). Contracting Office Address NCATS Section NIDA Office of Acquisition 6001 Executive Boulevard Suite 3151, MSC 9531 Bethesda, Maryland 20892-9531* *Use Rockville, MD 20852 for Fed-Ex/USPS/Courier/Hand-Delivery Points of Contact Primary Point of Contact: Kimberly Espinosa Contract Specialist Kimberly.espinosa@nih.gov Phone: (301) 827-3546 . NIHDA201800417 Department of Health and Human Services National Institutes of Health
8/3/18, 12:49 PM Two (2) Molecular Devices FLIPR Tetra high-throughput cellular screening systems and associated robotics and reagents, or brand name equal systems
(i) This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. (ii) The solicitation number is NIHDA201800417 and the solicitation is issued as a request for quotation (RFQ). This acquisition is for a commercial item and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures; FAR Subpart 13.5- Simplified Procedures for Certain Commercial Items; and FAR Part 12-Acquisition of Commercial Items, and is expected to exceed the simplified acquisition teshold. (iii) The solicitation document and incorporated provisions and clauses are those in effect tough Federal Acquisition Circular 2005-100, dated August 22, 2018. (iv) The associated NAICS code is 334516 and the small business size standard is 1,000 employees. This requirement is full and open with no set-aside restrictions. (v) NCATS seeks to purchase two (2) Molecular Devices FLIPR Tetra High-Toughput Cellular Screening Systems and associated robotics and reagents, or brand name equal systems. The FLIPR Tetra High-Toughput Cellular Screening System provides an automated solution for identifying early leads in the drug discovery process and for evaluating drug efficacy and toxicity. With simultaneous pipette and read function, the system supports fast kinetic cellular assays. It can be quickly configured based on library size, detection mode, screening format, assay and target. It is a fully integrated solution with a seamless transition from assay development to lead optimization. The FLIPR Tetra systems are commercially available and are customized with options to fit the specific laboratory needs. The brand-name requirements include: 1. One (1) FLIPR Tetra Base system, outfitted with: Aequorin Camera, ICCD (fluorescence and luminescence) (Part No. 0310-5148) Membrane Potential Optics Kit (Part No. 0200-6207) 1536 pin tool head kit with pins (Part No. N/A) 384 pin tool head kit with pins (Part No. N/A)2. One (1) FLIPR Tetra Base system, outfitted with: Aequorin Camera, ICCD (fluorescence and luminescence) (Part No. 0310-5148) Membrane Potential Optics Kit (Part No. 0200-6207) 1536 pin tool head kit with pins (Part No. N/A) 384 pin tool head kit with pins (Part No. N/A) TetraCycler Plate Handler (Part No. N/A) Customization to allow electrically generated atmospheric pressure plasma ionization/cleaning for a 1536-well pintool 3. Two (2) FLIPR Calcium 6 Assay Kit; Bulk Kit (Part No. R8191)4. Two (2) FLIPR Membrane Potential Blue, Explorer Kit (Part No. R8042)5. Two (2) FLIPR Membrane Potential Red, Bulk Kit (Part No. R8123)6. Two (2) Neurotransmitter Transporter Uptake Bulk Assay (Part No. R8174)7. Installation and Training (vi) Brand name or equal multimodal high-toughput cellular screening systems must have the following salient characteristics: Intensified CCD camera capable of both standard fluorescence and aequorin luminescence detection to enable membrane potential assays/detection User-configurable 384-, and 1536-well pipettors/pin tools User-exchangeable cell suspension option Intuitive, user-friendly software interface Internal plate handler for accelerated toughput Easy Integration into the Kalypsys Robotic Platform (vii) Delivery of the systems is to occur within ten (10) weeks after receipt of order. Delivery shall be made to the below address with FOB Destination. National Center for the Advancement of Translational Sciences Attention: Dr. Matthew Hall 9800 Medical Center Drive, Building B Rockville, MD 20850 Installation and on-site training shall occur shortly after delivery. The exact date and time will be determined by NCATS and the contractor. (viii) The Government plans to award a contract resulting from this solicitation. The resulting award will be made to the responsible offeror whose offer conforming to the solicitation will be most advantageous to the Government, price and other factors considered. The following factors shall be used to evaluate quotations: 1. Technical approach. Technical approach includes the extent to which the offeror conforms to the brand-name specifications and ability to meet delivery requirements. 2. Past performance (see FAR 13.106-2(b)(3)) 3. Price (vix) The following provisions / clauses apply to this acquisition: The provision at FAR 52.211-6, Brand Name or Equal The provision at FAR 52.212-1, Instructions to Offerors - Commercial Items The provision at 52.212-3, Offeror Representations and Certifications-Commercial Items. This provision is provided in full text as an attachment to this combined synopsis/solicitation. Offerors are to complete this provision and submit a completed copy with its offer. The clause at FAR 52.212-4, Contract Terms and Conditions - Commercial Items The clause at FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders-Commercial Items. This clause is provided in full text as an attachment to this combined synopsis/solicitation. NIH Invoice and Payment Provisions (2/2014). These provisions are provided as an attachment to this combined synopsis/solicitation. (xv) There are no additional contract requirement(s) or terms and conditions applicable to this acquisition. (xiv) The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement. (xv) Responses to this solicitation must include sufficient information to establish the interested parties' bona-fide capabilities of providing the product or service. The price quote shall include: unit price, list price, shipping and handling costs, delivery days after contract award, delivery terms, prompt payment discount terms, product or catalog number(s); product description; and any other information or factors that may be considered in the award decision. Such factors may include: past performance; special features required for effective program performance; trade-in considerations; probable life of the item selected as compared with that of a comparable item; warranty considerations; maintenance availability; and environmental and energy efficiency considerations. Respondents proposing on an equal product of the brand-name product specified in this announcement must provide, as part of their response: (a) product, catalog, model, and/or part number(s); (b) product description; (c) all relevant information and documentation that the item(s) offered meets the salient physical, functional, or performance characteristics as specified in the purchase description; quantity; estimated price or cost; shipping, handling, and/or installation charges; and delivery date after receipt of order. In addition the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." All responses must be received by 12:00pm EDT on Friday, September 7, 2018, and reference solicitation number NIHDA201800417. Responses may be submitted electronically to Kimberly Espinosa, Contract Specialist, at kimberly.espinosa@nih.gov. Fax responses will not be accepted. (xvi) The name and telephone number of the individual to contact for information regarding the solicitation is Kimberly Espinosa, Contract Specialist, 301-827-3546, kimberly.espinosa@nih.gov. NIHDA201800417 Department of Health and Human Services National Institutes of Health
8/27/18, 10:21 AM Two (2) Molecular Devices FLIPR Tetra systems or brand-name equal
Awarded Vendors: Stripes Global Inc.. Contract Award Dollar Amount: $1,273,284.00. Contract Award Date: 2018-09-28. NIHDA201800417 Department of Health and Human Services National Institutes of Health
10/1/18, 4:04 PM