Purchase Order 75N94021P00582
- Not listed
- This is a $19,000 firm fixed price purchase order awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to Frontage Laboratories, Inc., a full-service contract research organization (CRO). The contract is for the synthesis of SAMT-247 and an analog compound. Frontage Laboratories has previously supported NIDDK and the National Center for Advancing Translational Sciences through various federal contracts, providing services such as pharmacokinetic testing, in...
- This is a $36,000.00 firm fixed-price contract awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which is part of the National Institutes of Health (NIH), a civilian agency. The contract was awarded to Entrechem SL, a for-profit manufacturer located in Spain, to provide 100g each of two specialized chemical compounds, (1S,2S)-trans-N-Boc-Tetrahydro-3,4-furandiamine and (1R,2R)-trans-N-Boc-Tetrahydro-3,4-furandiamine. These compounds are needed as starting...
- This federal contract award is for the synthesis of Fmoc-thyclotide monomers, placed by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) with the prime contractor Frontage Laboratories, Inc. The $45,500.00 firm-fixed-price purchase order has an ultimate completion date of December 31, 2020. Frontage Laboratories, a minority-owned, Asian-Pacific American-owned business, has an established history of providing specialized research services to NIDDK and other NIH...
- The National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $90,000.00 firm fixed price purchase order contract to Frontage Laboratories, Inc. for the synthesis of thyclotides (R,R). The contract has no set-aside designation and was awarded on August 14, 2022 with an ultimate completion date of August 17, 2023. Frontage Laboratories, a minority-owned, Asian-Pacific American manufacturer of goods, has provided a range of research...
- This is a $40,500 firm fixed-price purchase order awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to Polyorg, Inc., a for-profit manufacturer located in Leominster, MA. The order is for specialized chemical reagents including Fmoc-PNA monomers and Bhoc Nucleobase Acids, which are essential starting materials for NIDDK's research on thyclotides - molecules with potential diagnostic applications. The purchase order was awarded on a sole-source basis under...
- This federal contract award, valued at $50,000.00, was issued by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), a civilian agency within the Department of Health and Human Services, to the prime contractor Entrechem SL. The contract is for the purchase of 100 grams each of two specific enantiomers of trans-N-Boc-1,2-tetrahydro-3,4-furandiamine. These chemical compounds are needed as starting materials for the NIDDK's research into developing thyclotides, which...
- This federal contract award, valued at $51,248.00, was issued by the National Institutes of Health's National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to Polyorg, Inc., a manufacturer of specialty chemicals. The award was a firm fixed-price purchase order for the delivery of 80 grams of A(Bhoc)-OH, 120 grams of C(Bhoc)-OH, and 160 grams of G(Bhoc)-OH, which are key building blocks for the development of thyclotides and cyclopentane peptide nucleic acids. These materials...
- This is a $117,000.00 firm fixed price purchase order awarded to Frontage Laboratories, Inc. by the Department of Health and Human Services' National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The contract is for Frontage Laboratories to provide a range of preclinical research services, including pharmacokinetic testing, in vivo studies, compound synthesis, and fertility assessments, to support the development of new therapies and...
- This is a $93,800 fixed-price purchase order contract awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to Frontage Laboratories, Inc., a full-service contract research organization (CRO). The contract is for pharmacokinetic testing and research services related to the compound MTS-IV-39. Frontage Laboratories has a history of providing a range of research services to NIDDK and the National Institutes of Health, including compound synthesis, in vivo studies,...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health (NIH) awarded a $45,390.05 firm-fixed-price purchase order to Biotage, LLC for a base year plus four option years of maintenance and support services for the Alstra Peptide Synthesizer. This equipment is used by the NIDDK's Laboratory of Chemical Physics to conduct research on protein folding, ligand binding, and peptide aggregation. The solicitation was not competitively bid, as...
This is a $162,000 firm fixed-price purchase order awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to Frontage Laboratories, Inc., a full-service contract research organization (CRO), for the synthesis of thyclotides and cyclopentane-constrained peptide nucleic acids. The award was made on a sole-source basis under simplified acquisition procedures, as Frontage was determined to be the only source capable of scaling up the production of these specialized, synthetic research compounds to the required quantities. The purpose is to support NIDDK's research on developing new diagnostic probes to detect nucleic acid sequences associated with diseases, as part of the institute's broader mission of conducting and supporting research on serious public health issues. The contract has a 90-day period of performance and does not include a set-aside designation.
Name | Description | Solicitation Number | FederalAgency | Type | PostedDate |
|---|---|---|---|---|---|
Procurement of Services for the Synthesis of Thyclotides (R, R) and (S, S)-trans-Tetrahydrofuran- and Cyclopentane constrained peptide nucleic acids | NICHD-21-207 | Department of Health and Human Services National Institutes of Health National Institute of Child Health and Human Development | Pre-Solicitation 1/1 | 7/22/21, 1:30 PM |
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | Not listed | $162.0k | 8/9/21 |