This federal contract award, with ID NNX17AE48G, was granted by the National Aeronautics and Space Administration (NASA) to the University of Florida (UF) Division of Sponsored Research. The contract, valued at $244,177.39, is a grant for research on the effects of microgravity on the cardiovascular system, specifically the interaction between endothelial cells, smooth muscle cells, and endothelial stem/progenitor cells. This research is aimed at developing cell-based countermeasures to address the challenges of cardiovascular deconditioning experienced by astronauts upon returning from space flights. The contract is not designated as a set-aside. The research is inspired by data from the GeneLab "Spaceflight of Human Umbilical Vein Endothelial Cells (SPHINX)" study, which revealed important genetic changes in endothelial cells under real microgravity conditions. This contract seeks to expand on those findings by investigating the functional behaviors of these cell types under modeled microgravity conditions.
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