Delivery Order EPD13013-0003

Reaction Biology Corporation was awarded a $109,470 firm fixed price purchase order by the Department of Health and Human Services' National Institutes of Health's National Institute on Drug Abuse to provide compound testing services in support of kinase enzyme inhibition and cardiac ion channel block research. As the prime contractor, Reaction Biology will test 330 small molecule compounds using its Kinase HotSpot and automated patch-clamp assay platforms to characterize inhibition of kinase...

The Department of Health and Human Services' National Institutes of Health National Center for Advancing Translational Sciences awarded a $42,840.00 firm fixed price purchase order to AAT Bioquest, Inc., a minority-owned, woman-owned small business, for the delivery of 20 units of the Screen Quest Calbryte-520 Probenecid-Free and Wash-Free Calcium Assay Kit. This requirement was solicited and awarded on a non-competitive basis for a commercial item under simplified acquisition procedures. The...

The U.S. Food and Drug Administration (FDA) awarded a $106,675.00 firm fixed-price purchase order contract to Olink Proteomics Inc., a foreign-owned, for-profit biotechnology company, for a proteomic analysis of cancer patient plasma samples. The contract, which has no set-aside designation, will be performed at Olink's facility in Waltham, Massachusetts and involves the comprehensive analysis of over 5,000 proteins across 100 plasma samples using Olink's advanced multiplex immunoassay...

The National Institute of Environmental Health Sciences (NIEHS) awarded a Firm Fixed Price BPA Call contract to Promega Corporation for a Dual-Luciferase Reporter Assay System on July 9, 2015, with a ceiling value of $6,880.85. This contract, which was not designated as a set-aside, represents a task order issued under Promega's larger Blanket Purchase Agreement vehicle with the National Institutes of Health. The place of performance is Madison, Wisconsin, where Promega maintains its...

This is a firm-fixed-price delivery order awarded by the Environmental Protection Agency's (EPA) Office of Research and Development to Cyprotex US LLC, a foreign-owned, for-profit contract research organization. The $546,940 contract is for a "Steroidogenesis Assay (Assay and Multiplexed Endpoint Sample Analysis)", which supports the EPA's High Throughput Toxicokinetics program. This work will enable the EPA to rapidly and cost-effectively generate toxicokinetic data on hundreds of...

The Department of Health and Human Services Food and Drug Administration awarded a firm-fixed price purchase order contract worth $249,210.00 to Molecular Devices LLC, a subsidiary of Danaher Corporation, for an ImageXpress Micro 4 High Content Screening System. The system is intended to enable the FDA's National Center for Toxicological Research to perform measurements of intracellular calcium flux in human-induced pluripotent stem cell-derived cardiomyocytes to better understand the mechanisms...

Reaction Biology Corporation has been awarded a $100,560 firm fixed price purchase order by the Department of Health and Human Services' National Institutes of Health National Center for Advancing Translational Sciences to provide GAMMA 33P ATP Kinase Assay and NanoBRET Kinase Assay testing services. As a prime contractor, Reaction Biology will utilize its Kinase HotSpot and Methyltransferase HotSpot platforms to test libraries of novel compounds against panels of wild-type kinases and...

The U.S. Department of Agriculture awarded a firm fixed-price purchase order to Biocrates Life Sciences AG, an Austrian metabolomics technology company, on August 4, 2020, with a ceiling value of $54,208. The contract calls for the delivery of Biocrates MXP QUANT 500 assay kits, which are advanced metabolomic analysis tools used for precise, mass spectrometry-based quantification of metabolites in biological samples. The solicitation was posted on July 23, 2020, with a due date of July 30, 2020,...

The National Institutes of Health's National Center for Advancing Translational Sciences awarded a $3.86 million firm fixed price purchase order to Molecular Devices LLC for the acquisition of five Molecular Devices ImageXpress Confocal High-Content Imaging Systems, one FLIPR Penta high-throughput cellular screening system, along with associated software, services, consumables, installation, training, customization, maintenance, and technical support. The products and services are to support the...

This firm fixed price purchase order awards $56,313 to Cyprotex US LLC to provide in vitro absorption, distribution, metabolism, excretion, and toxicity (ADMET) characterization services in support of the Department of Health and Human Services (HHS), National Institutes of Health (NIH), National Cancer Institute's (NCI) Developmental Therapeutics Program (DTP). The contractor will evaluate two small molecule drug candidates total across 11 specified in vitro ADMET assays, including metabolic...