Definitive Contract 75A50123C00031
- Not listed
- The U.S. Department of Health and Human Services, Office of the Assistant Secretary for Preparedness and Response (ASPR), awarded a $726,389.15 firm fixed-price definitive contract to Tiba Biotech LLC on April 30, 2024. This research and development effort, designated as AOI#25(FASTX), focuses on developing a respiratory virus treatment utilizing lung-targeted small interfering RNA (siRNA) delivery technology. The contract carries no set-aside designation and is scheduled for completion by...
- The U.S. Department of Health and Human Services, Office of the Assistant Secretary for Preparedness and Response (ASPR), awarded a $749,000 firm fixed-price contract to Gen1E Lifesciences Inc. on September 22, 2023, for support in advancing patient stratification and endotyping approaches related to GEN-1124, a novel therapeutic candidate for acute respiratory distress syndrome (ARDS). The contract, which carries no set-aside designation, is structured as a definitive contract with a completion...
- This federal contract award, valued at $749,549.00, was made by the Office of the Assistant Secretary for Preparedness and Response (ASPR) to Immunexpress Inc., a for-profit foreign-owned company. The contract is for the "ASSESSMENT & TRIAGE OF PATIENTS WITH ESCALATING SIGNS OF COVID-19 DISEASE USING A HOST RESPONSE TEST FOR SEPSIS" and is a definitive, firm-fixed-price contract with a period of performance ending on June 10, 2023. The contract award originated from a Broad...
- This is a federal contract award from the Office of the Assistant Secretary for Preparedness and Response (ASPR), a civilian agency, to Lovelace Biomedical and Environmental Research Institute, Inc. (LBERI), a not-for-profit research organization. The award is for the development of a murine (mouse) model of pulmonary chlorine exposure, with a ceiling value of $1,047,135.50 and a period of performance ending on September 30, 2020. The contract is a cost-plus-fixed-fee type, without any set-aside...
- This is a $897,471 firm-fixed-price delivery order contract awarded by the Food and Drug Administration (FDA) to Lovelace Biomedical and Environmental Research Institute, Inc. (LBERI), doing business as Inhalation Toxicology Research Institute. The contract is part of a larger In Vivo Toxicology of Tobacco 2015-2020 indefinite-delivery, indefinite-quantity (IDIQ) contract vehicle. LBERI, a non-profit contract research organization, will provide preclinical research services to support the...
- The Department of Health and Human Services Office of the Assistant Secretary for Preparedness and Response awarded Esperovax Inc. a $484,643 firm fixed price definitive contract to develop host-directed therapeutic candidates for mitigating long-term effects of respiratory distress. The contract was awarded under Special Instructions 019 of the Easy Broad Agency Announcement BAA-20-100-SOL-0002, which sought proposals for candidates aiding long-term outcomes from lung injury through Area of...
- The U.S. Department of Health and Human Services' Office of the Assistant Secretary for Preparedness and Response awarded a $70,000 firm fixed-price contract to Oncotelic Inc. to develop TGF-β therapeutics against the long-term effects of respiratory distress post COVID-19. The contract, which does not have a set-aside designation, has a period of performance ending on June 30, 2023. This contract supports the agency's efforts to address the medical challenges posed by the COVID-19 pandemic.
- Battelle Memorial Institute, a large nonprofit research and development organization headquartered in Columbus, Ohio, was awarded a delivery order valued at $18.08 billion by the Office of the Assistant Secretary for Preparedness and Response (ASPR) on September 29, 2025, for a contract extending through August 30, 2030. This cost-plus-fixed-fee delivery order supports the development and use of a human-relevant small animal model of sulfur mustard-induced inhalation injuries to screen potential...
- The Food and Drug Administration awarded a firm fixed-price purchase order valued at $800,622.70 to Trillamed LLC, a Service-Disabled Veteran-Owned Small Business headquartered in Bingham Farms, Michigan, on September 24, 2024. The contract, designated "ISOLATOR," has an ultimate completion date of August 15, 2026, and will be performed in Jamaica, Queens, New York. This award represents a non-set-aside procurement, allowing Trillamed to compete directly against all eligible vendors....
- This is a definitive contract awarded by the Office of the Assistant Secretary for Preparedness and Response, a civilian federal agency, to Swaza Inc., a minority-owned, for-profit, woman-owned small business, for research and development of a breakthrough nanofluid breathing aid to treat acute respiratory distress. The Firm Fixed Price contract has a ceiling value of $372,753.57 and a completion date of October 7, 2025. The contract is not associated with a larger vehicle and does not have a...
Isola Therapeutics Inc. has been awarded a $749,999 firm fixed-price definitive contract by the Office of the Assistant Secretary for Preparedness and Response (ASPR) to conduct research and development for endobronchial lavage (EBL) as a preventative and therapeutic intervention for lung damage caused by pulmonary chemical agents. The contract, awarded on July 12, 2023, falls under the REDIRECT (Repurposing Drugs in Response to Chemical Threats) initiative, Area of Interest #15, and is being performed in Minneapolis, Minnesota, with a completion date of July 11, 2025. No set-aside designation was used for this procurement. ASPR's REDIRECT program focuses on identifying existing drugs and therapeutic approaches that can be rapidly adapted to address chemical, biological, radiological, and nuclear threats. This contract represents investment in developing endobronchial lavage techniques—a bronchoscopic procedure involving lung irrigation—as a medical countermeasure for personnel exposed to toxic pulmonary agents. The research aims to establish protocols and evidence supporting EBL's use in both preventing and treating damage from chemical weapons or industrial chemical exposures, potentially supporting emergency preparedness and response capabilities.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| P00001 | Other Administrative Action | $0 | 6/20/24 | |
| Not listed | Not listed | $750.0k | 7/11/23 |