Federal contract opportunity HHS-FDA-RFI-1072704 for analytical laboratory instrument manufacturing at Food and Drug Administration Office of Acquisitions and Grants Services, response was due Jul 13, 2010.

Due
Solicitation Number
HHS-FDA-RFI-1072704
Contract Number(s)
None listed
Additional Info Link
None listed
Set-Aside
No Set-Aside Used
Synopses View

Description: (1) One Microwave Digestion System and (1) One Microwave Synthesis System

This is a RFI to determine the availability and capability of small businesses (i.e., certified 8(a), Small Disadvantaged, and HUBZone firms; veteran and service-disabled veteran-owned small businesses, and woman-owned small businesses) for (1) One Microwave Digestion System and (1) One Microwave Synthesis System.


This information is being sought for information and planning purposes only and shall not be construed as a solicitation or as an obligation on the part of the Food and Drug Administration (FDA). No official solicitation exists; therefore, please do not request a copy of a solicitation. If in the future an official solicitation is released, there is no guarantee that sources responding to this will be included on the source list. No telephone inquiries will be accepted.


Objectives:


The FDA requires two automated microwave systems for use within the NCTR/ORA Nanotechnology Core Facility. The first system shall be used to develop methodologies for the acid digestion of FDA regulated products; prior to spectroscopic determination for the presence of nanomaterials. The second system shall allow ORA to synthesize various nanomaterials and/or nanparticles for utilization as analytical controls.


Draft Scope of Work:


(1) Microwave Digestion System


The system shall include at least the following items:
• Microwave Digester with accessories kit
• Sample automation module
• Laptop style computer
• Software capable of operating the microwave from the laptop
• System onsite installation and familiarization
• 40 Each - Quartz digestion vessels with an approximate volume of 35mL
• 40 Each - Teflon liners for use in the quartz digestion vessels
• 40 Each - Magnetic stir bars
• 500 Each - Disposal caps for the quartz digestion vessels



Draft Specifications for Microwave Digestion System:
• Due to laboratory space requirements, the microwave shall be of bench top design, and occupy space no larger than 2.5 ft X 2.5 ft.
• System shall have built in computer control system with integrated visual display of pressure and temperature data. Though it may be operated via a computer, it should not require the use of a standalone computer.
• System shall utilize a single mode 300 watt microwave applicator with minimum power density of 900 watts/liter. The power density shall be adjustable during a sample sequence.
• The system shall have an active venting system to remove gaseous products during the course of a sample digestion. This requirement allows for the digestions of larger samples sizes. This pressure release shall be able to vent the reaction vessel during the reaction, upon reaction completion, or if the reaction should exceed the designated pressure requirements.
• System shall have the ability to automatically cool the digestate at end of sample run.
• The system shall be amendable to the use of concentrated acids, such as nitric and hydrochloric.
• System shall have magnetic stirring capability.
• System shall be equipped with 3 safety interlocks in accordance with Code of Federal Regulations 1030.3.4.
• The system shall allow the sequential digestion of samples.
• The system shall have the ability to monitor and control both temperature and pressure for every individual sample. The temperature control system should be non-invasive and have a working range of 0 - 300 °C.
• The sample automation module (autosampler) shall allow for a minimum of 36 digestion vessels, with each vessel having an approximate volume of 35 mL.
• System shall have digestion vessel options, which can handle up to 0.5 g sample size with Teflon lining or vessels with variable sample volume up to 35 mL.
• The system shall incorporate an air delivery system to remove vapor from the system during any pressure release phase.
• System shall have corrosive resistant protective linings.
• System shall operate using standard 120V power supply.
• System shall have full 1 year warranty following installation.
• Vender shall provide application and operation manuals.



(1) Microwave Synthesis System


The system should include at least the following items:
• Microwave Digester with accessories kit
• Sample automation module
• Laptop style computer
• Software capable of operating the microwave from the laptop
• System onsite installation and familiarization
• 25 Each - 35mL pressure vials and caps
• 100 Each - 10mL pressure vials and caps


Draft Specifications for Microwave Synthesis System:
• Due to laboratory space requirements, the microwave shall be of bench top design, and occupy space no larger than 2.0 ft X 2.0 ft.
• System shall utilize a single mode cavity design and provide a uniform power density of 900 watts/liter. The power density shall be adjustable during a sample synthesis, to insure efficient energy coupling.
• System shall have built in computer control system with integrated visual display of pressure and temperature data. Though it may be operated via a computer, it should not require the use of a standalone computer.
• The system shall contain an automation module with a minimum of 12 sample locations.
• System shall be equipped with 3 safety interlocks in accordance with Code of Federal Regulations 1030.3.4.
• The system shall allow synthesis in both sealed and atmospheric vessels. Sealed vessels should allow volumes up to 80 mL. Atmospheric vessels should allow volumes up to 125 mL.
• In order to maximize energy loading, the system shall have the ability to cool the reaction while applying microwave energy. The cooling rate shall be a minimum of 1 °C per second.
• The system shall have a pressure control system with feedback control.
• System shall have excess pressure venting maintaining minimum pressure of 30 psi and delivering system while maintaining complete enclosed and captured system.
• The system shall have the ability to stir the reaction contents of both sealed and atmospheric synthesis vessels.
• System shall have a sample automation system (autosampler) which can handle a minimum of 12 samples, where each and every sample can undergo individual reaction conditions with respect to temperature, time, magnetic stirring speed and microwave energy
• Sealed synthesis vessels shall employ a vent and re-seal mechanism to insure the safety of the system.
• System shall operate using standard 120V power supply.
• System shall have full 1 year warranty following installation.
• Contractor shall provide application and operation manuals.


We anticipate using a firm fixed price purchase order.


Viable parties shall provide the following:


Part A. Capabilities and Technical Experience - Provide a capability statement describing how your company would provide for (1) One Microwave Digestion System and (1) One Microwave Synthesis System.


Part B. Size of Business- Please provide your business size and submit copies of any documentation such as letters or certificates to indicate the firm's status.


Part C. Organizational Conflict of Interest (OCI) - If any, provide disclosure of business activities of your company, your affiliates, your team members and affiliates of your team members which create either a conflict of interest or the appearance of a conflict of interest in the Evaluation for (1) One Microwave Digestion System and (1) One Microwave Synthesis System.



Part D. Cost Estimate - Provide a cost/price estimate in accordance with FAR Part 10, Market Research for (1) One Microwave Digestion System and (1) One Microwave Synthesis System.



Part E. Small Business - Describe your ability to meet the requirements in accordance with 52.219.14 - Limitation on Subcontracting.


Responses shall be:


 identified with the RFI number ;
 no more than ten (10) pages in length;
 not submit marketing materials;
 submitted to the email as indicated above.


FDA makes no implied or in fact contract by issuing this RFI. Acknowledgement of receipt of responses will not be made, nor will respondents be notified of the FDA's view of the information received.