Schrodinger Suite Renewal

Added: Jun 29, 2016 5:27 pm Notice Type: Combine Synopsis/Solicitation
Original Posted Date
Response Date:
Original Set Aside: Total Small business
Classification Code
NAICS 511210
Synopsis: This is a combined synopsis/ solicitation for laboratory equipment in accordance with FAR Regulation (FAR) 12.102(g) and in the format of Subpart 12.6 and 13.5 as supplemented with additional information included in this notice.

This announcement constitutes the only solicitation. Quotations are being requested and a written solicitation will not be issued. The solicitation number is FDA- SOL -16-1168946 and is issued as a Request for Proposals (RFP). This solicitation document incorporated all mandatory commercial item provision and clauses that are in effect through the Federal Acquisition Circular 2005- 88-1 dated 6/06/2016

The North American Industrial Classification System is 511210 and the small size standard is 35M 500L This is a firm fixed price contract and is being issued as a "Brand Name or Equal to". If OR EQUAL items are proposed, the Offer or shall provide product specifications for those items proposed. All products proposed (whether brand name listed or OR EQUAL items proposed) must satisfy the functional requirements/salient characteristics set forth in this document.
Title: Schrödinger Suite or equal to License Renewal - Chemical Simulation Software

1.0 Background

The Division of Bioinformatics and Biostatistics of the National Center for Toxicological Research (NCTR) of the Food and Drug Administration (FDA) is currently conducting research sponsored by the Center for Tobacco Products (CTP.) A crucial component of this research involves chemical structure analysis. The FDA requires the latest generation of chemical simulation software to provide the Government with comprehensive tools required for analysis of chemical structures, and quantitative structure-activity relationships (QSARs), as well as visual graphics, to enable FDA efforts in evaluation of the effects of tobacco products on the public health, and to facilitate the communication of FDA's research findings.

The FDA has been utilizing the Schrödinger Suite chemical simulation software for several years to fulfill this requirement.
Salient Characteristics of the Requirement The Schrödinger Suite is a comprehensive package of chemical simulation software engineered specifically for pharmaceutical and biotechnology research. The predictive power of Schrödinger's software accelerates research and development activities, and provides the precision tooling for the analysis needed to support FDA research endeavors. In order to be considered an "equal" solution, any alternative solution proposed must be compatible with the current simulation software already deployed at FDA NCTR. For the purposes of this solicitation, FDA defines compatible as meaning that there will be no communication, integration, performance, maintainability issues in the interconnection of solutions with different configurations.

2.0 Objective
The objective of this solicitation is to obtain renewal of the licenses for the Schrödinger Suite or equal to Chemical Simulation Software.

3.0 Scope
The FDA is seeking license renewal for the Schrödinger Suite or equal to Chemical Simulation Software. In order to preserve scientific integrity of our research, it is imperative that these licenses or equal type licenses be renewed/provided. The license renewals would be for a base year plus two option years. Period of performance 7/16/2016- 7/15/2019.

The Schrödinger Suite or equal chemical simulation software must be provided by authorized Schrödinger or equal resellers of chemical simulation software and licenses to meet the FDA Requirement.

The FDA intends to award a Firm Fixed price contract to meet the requirements of this solicitation.

4.0 Deliverables
An example of a product that meets our needs is as follows:

25 Tokens for interchangeable library including Canvas, CombiGlide, ConfGen, Core Hopping, Desmond, Epik, Field-based QSAR, Glide, Jaguar, Jaguar pKa, Liason, LIgPrep, MacroModel, Pase, Shape Screening, Prime, PrimeX, QikProp, Qsite, Strike, XP Visualizer. All software must be Windows 7 64-bit compatible. Period of performance: 7/17/2016- 7/15/2017, Option year 1 7/16/2017-7/15/2018, Option year 2 7/16/2018- 7/15/2019

Maestro Access License 7/16/2016- 7/15/2017, Option year 1 7/16/2017- 7/15/2018, Option year 2 7/16/2018-7/15/2019

KNIME access License 7
/16/20160 7/15/2017, Option year 1 7/16/2017-7/15/2018, Option year 2 7/16/2018- 7/15/2019
OPLSe AccessLicense 7/16/2016- 7/15/2017,Option year 1 7/16/2017- 7/15/2018, Option year 2 7/168/2018- 7/15/219

5.0 Place of Performance
The software licenses shall be renewed electronically, and will be installed on workstations located at:

US FDA
National Center for Toxicological Research
3900 NCTR Road, 5C
Jefferson, AR 72079

6.0 Period of Performance
The Period of Performance is for one year plus two option years 

7.0 Evaluation Criteria
The Government will select the bidder whose offer best conforms to the solicitation and is most advantageous and provides the best value to the Government. The ability to provide the requested chemical simulation software and support is the most important factor. If proposals are equal in their technical merit, lowest price will become the determining factor.
8.0 Other Pertinent Information or Special Considerations

8.1 Section 508
The following HHSR clause applies to this task order:

HHSR 352.239-73 Electronic and Information Technology Accessibility (January 2010)
Pursuant to Section 508 of the Rehabilitation Act of 1973 (29 U.S.C. 794d) as amended by Public Law 105-220 under Title IV (Rehabilitation Act Amendments of 1998), all Electronic and Information Technology (EIT) developed, procured, maintained, and/or used under this contract shall be in compliance with the ‘‘Electronic and Information Technology Accessibility Standards'' set forth by the Architectural and Transportation Barriers Compliance Board (also referred to as the ‘‘Access Board'') in 36 CFR part 1194. The complete text of Section 508 Final Standards can be accessed at http://www.access-board.gov/sec508/standards.htm.
The standards applicable to this requirement are:

Subpart B -- Technical Standards
§ 1194.21 Software applications and operating systems.
(a) When software is designed to run on a system that has a keyboard, product functions shall be executable from a keyboard where the function itself or the result of performing a function can be discerned textually.
(b) Applications shall not disrupt or disable activated features of other products that are identified as accessibility features, where those features are developed and documented according to industry standards. Applications also shall not disrupt or disable activated features of any operating system that are identified as accessibility features where the application programming interface for those accessibility features has been documented by the manufacturer of the operating system and is available to the product developer.
(c) A well-defined on-screen indication of the current focus shall be provided that moves among interactive interface elements as the input focus changes. The focus shall be programmatically exposed so that assistive technology can track focus and focus changes.
(d) Sufficient information about a user interface element including the identity, operation and state of the element shall be available to assistive technology. When an image represents a program element, the information conveyed by the image must also be available in text.
(e) When bitmap images are used to identify controls, status indicators, or other programmatic elements, the meaning assigned to those images shall be consistent throughout an application's performance.
(f) Textual information shall be provided through operating system functions for displaying text. The minimum information that shall be made available is text content, text input caret location, and text attributes.
(g) Applications shall not override user selected contrast and color selections and other individual display attributes.
(h) When animation is displayed, the information shall be displayable in at least one non-animated presentation mode at the option of the user.
(i) Color coding shall not be used as the only means of conveying information, indicating an action, prompting a response, or distinguishing a visual element.
(j) When a product permits a user to adjust color and contrast settings, a variety of color selections capable of producing a range of contrast levels shall be provided.
(k) Software shall not use flashing or blinking text, objects, or other elements having a flash or blink frequency greater than 2 Hz and lower than 55 Hz.
(l) When electronic forms are used, the form shall allow people using assistive technology to access the information, field elements, and functionality required for completion and submission of the form, including all directions and cues.
Subpart C -- Functional Performance Criteria
§ 1194.31 Functional performance criteria.
(a) At least one mode of operation and information retrieval that does not require user vision shall be provided, or support for assistive technology used by people who are blind or visually impaired shall be provided.
(b) At least one mode of operation and information retrieval that does not require visual acuity greater than 20/70 shall be provided in audio and enlarged print output working together or independently, or support for assistive technology used by people who are visually impaired shall be provided.
(c) At least one mode of operation and information retrieval that does not require user hearing shall be provided, or support for assistive technology used by people who are deaf or hard of hearing shall be provided.
(d) Where audio information is important for the use of a product, at least one mode of operation and information retrieval shall be provided in an enhanced auditory fashion, or support for assistive hearing devices shall be provided.
(e) At least one mode of operation and information retrieval that does not require user speech shall be provided, or support for assistive technology used by people with disabilities shall be provided.
(f) At least one mode of operation and information retrieval that does not require fine motor control or simultaneous actions and that is operable with limited reach and strength shall be provided.
Subpart D -- Information, Documentation, and Support
§ 1194.41 Information, documentation, and support.
(a) Product support documentation provided to end-users shall be made available in alternate formats upon request, at no additional charge.
(b) End-users shall have access to a description of the accessibility and compatibility features of products in alternate formats or alternate methods upon request, at no additional charge.
(c) Support services for products shall accommodate the communication needs of end-users with disabilities.
8.2 Other provisions and clauses
FAR 52.211-6 Brand Name or Equal Clauses and provisions are incorporated by reference and apply to this acquisition.

Responses to this notice must be sent via email to Karen.conroy@fda.hhs.gov . No phone calls will be accepted.

9.0 Instruction to Quoters
.Quoters shall comply with the provision at FAR 52.212-1(b) and submit an electronic copy to Karen Conroy via email to karen.conroy@fda.hhs.gov

• The Quoter shall submit a technical volume and a pricing volume. Each volume should include the information specified below:

Volume One
• Demonstrates the Quoters capability to meet each requirement as described in the Statement of Work.
• Volume one shall not exceed five pages describing how they can perform.

Volume Two

• Quoters shall include a completed copy of the provision FAR 52-212-3 Offeror Representations and Certifications- Commercial Items (March 2015) which can be accessed electronically from the INTERNET at the following address: http://farsite.hill.af.mil/.
• FAR 52212-7 Option to extend the terms of the contract
• Quoters responding to this RFP must be registered with the System for Award Management (SAM), hht://www.sam.gov.
• FAR 52-212-4 Contract Terms and Conditions- Commercial Item (May 2015) and FAR 52.212-5 Contract Terms and Conditions Required to Implement Statutes or Executive Orders-Commercial June 2016
Items (May 2015, applies as follows: 52.233.-3, 52.233-4, 52.203-6, 52.219-6,
52.219-8, 52.222-3, 52.222-21, 52.222-26, 52-222-35, 52.222-36, 52.222-37
52.225-13, 52.232-33. and 52.239-1.

• FAR provisions and clauses may be found at http://www.acquistiion.gov/far/index.html

• Quoters that can provide and meet the above requirements shall submit a written quotation. Submission must be received via email no later than (July, 11 2016 2:30pm eastern time). Questions shall be received no later than (July 6, 2016 2;30pmeastern time).
Unlimited number of pages

9.0 Point of Contact
Karen Conroy
One Montvale Ave., 4th floor
Stoneham, MA 02180
781-587-7452
karen.conroy@fda.hhs.gov