Multi-photon Micrscopy System with 3D Spatial Light Modulator (SLM) Photostimulation

Closed Pre-Solicitation Posted

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Solicitation number
NIMH-20-003931
Agency
National Institute on Drug Abuse National Institutes of Health, Department of Health and Human Services
Responses due
Set-aside
No set-aside

Opportunity facts

NAICS code
333314 Optical Instrument and Lens Manufacturing
PSC
6640 Laboratory Equipment And Supplies
Place of performance
Bethesda MD 20892 USA

Notice details come from SAM.gov. Updated .

About this opportunity

The National Institute of Mental Health seeks to purchase one Ultima 2P Plus multi-photon microscopy system with 3D spatial light modulator photostimulation or equal product. Key requirements for the system include a scanning field of view of 1.4mm x 1.4mm, 3D volume imaging with an electrically tunable lens, close proximity detectors, 2" collection optics, synchronization via BNC, a rotating nosepiece, resonant scanning add-on, optogenetics capabilities, 3D SLM photostimulation, moving microscope translation, over 1000 frames per second imaging, high efficiency GaAsP detectors, timing and recombination unit, and tiling software. Delivery is requested by October 30, 2020 to identify distinct cortical subnetworks during behavioral conditions at the National Institutes of Health in Bethesda, Maryland.

There is no set-aside designation for this procurement. The primary NAICS code is 333314 for optical instrument and lens manufacturing while the main PSC code is 66 for scientific equipment and services. No incumbent or current contractors are identified. The period of performance is one year after installation of the single multi-photon microscopy system.

Notice text

Base Notice:  Multi-photon Micrscopy System with 3D Spatial Light Modulator (SLM) Photostimulation

Notice Type:             

Sources Sought

Posted Date:

June 16, 2020

Classification Code:

66 Scientific Equipment and Services

NAICS Code:

333314 Optical Instrument and Lens Manufacturing

NOTICE INFORMATION

Agency/Office:

National Institutes of Health

Location:

National Institute on Drug Abuse

Title:

Multi-photon Micrscopy System with 3D Spatial Light Modulator (SLM) Photostimulation

Description(s):

The National Institute of Mental Health (NIMH) is the lead Federal Agency for research on mental illnesses.  The mission of the NIMH is to transform the understanding and treatment of mental illnesses through basic and clinical research, paving the way for prevention, recovery, and cure.

The Unit on Functional Neural Circuits (UFNC) focuses specific circuits and neuronal types that enable internally-generated brain activity to interact with sensation, with emphasis on different types of cortical GABAergic (gamma-aminobutyric acid) neurons. Our project aims to delineate the functional connectivity among related brain areas, to identify the behavioral relevance of these circuits, to understand the computations these circuits perform, and to uncover their developmental specificity and plasticity. One of the aims is identifying different cortical subnetworks during different behavioral conditions. Our study will greatly benefit from using a multiphoton microscope to image and manipulate specific populations of neurons using 3D spatial light modulator (SLM) photostimulation from awake animals. This will facilitate our research to achieve more comprehensive understanding of specific neural circuits and the relevant behavior.

The purpose ofthis acquisition is to purchase a Ultima 2P Plus multi-photon micrscopy system with 3D spatial light modulator (SLM) photostimulation  or “equal” multi-photon micrscopy system with 3D spatial light modulator (SLM) photostimulation.  The purchase is required  to identify functionally distinct cortical subnetworks during different behavioral conditions. The Unit on Functional Neural Circuits relies on a two-photon microscope system to monitor large population of neurons with high spatiotemporal resolution while manipulating specific population of neurons.

The salient physical, functional, or performance characteristics that “equal” products must meet are specified in the purchase description.

Primary Point of Contact:

Robin Knightly

Contract Specialist

Robin.Knightly@nih.gov

Phone: (301) 827-5302

Secondary Point of Contact:

Valerie Whipple

Contract Officer

Valerie.Whipple@nih.gov

Phone:  (301) 827-5218

Contracting Office Address:

11601 Landsdown St

Bethesda, MD  20892-9559

United States

Place of Contract Performance:

National Institutes of Health

Porter Neuroscience Research Center, Bldg 35

Bethesda, MD  20892

Attachments

Files attached to this notice, newest first
File Type Posted
20-003931- Purchase Description.pdf PDF

Notice history

Notices posted for this opportunity, newest first
Notice Type Posted
Multi-photon Micrscopy System with 3D Spatial Light Modulator (SLM) Photostimulation Latest solicitation Solicitation
Multi-photon Micrscopy System with 3D Spatial Light Modulator (SLM) Photostimulation This notice · Original Pre-Solicitation

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