Integrative Epidemiological Studies

The purpose of this amendment is to amend Section L. c. 1. Accordingly, Section L. c. 1. Type of Contract and Number of Awards on Page 59 of the solicitation is deleted in its entirety and replaced with the following: It is anticipated that one award will be made from this solicitation and that the award will be made on/about November 30, 2018.

Proposal Due Date: April 6, 2018; 2:00PM Eastern (Unchanged)

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Added: Apr 04, 2018 11:03 am

The purpose of this amendment is to amend Section L. c. 1. Accordingly, Section L. c. 1. Type of Contract and Number of Awards on Page 59 of the solicitation is deleted in its entirety and replaced with the following: It is anticipated that one award will be made from this solicitation and that the award will be made on/about November 30, 2018.

Proposal Due Date: April 6, 2018; 2:00PM Eastern (Unchanged)

NOTICE OF SOLICITATION
Integrative Epidemiological Studies.

Added: Mar 05, 2018 4:41 pm NOTICE OF SOLICITATION

Integrative Epidemiological Studies

Pre-Solicitation Notice: N02CP81000-87
Contracting Office Address
Department of Health and Human Services
National Institutes of Health (NIH)
National Cancer Institute (NCI)
Office of Acquisitions
9609 Medical Center Drive, Room 1E612, MSC 9705
Bethesda, MD 20892-9705
Note: This synopsis follows a Sources Sought notice that was released on November 20, 2017 under
HHS-NIH-NCI-SBSS-ETSB-1000-87
THIS IS A NOTICE OF INTENT, NOT A REQUEST FOR PROPOSAL. A SOLICITATION WILL BE ISSUED ON A LATER DATE.
Title: Integrative Epidemiological Studies
Description:
The National Cancer Institute (NCI), Integrative Tumor Epidemiology Branch (ITEB) advances the understanding of cancer etiology and progression through integrative analyses of environmental and germline risk factors with comprehensive data on histological and molecular profiling of tumors and their precursors, including somatic genomic analyses. The branch also develops methods to support this cutting-edge research.
ITEB employs molecular pathology, somatic and germline genomics, and epidemiology to identify environmental and germline risk factors for cancer. The ITEB research program includes case-control, cohort, family, and cross-sectional studies. Investigators in the branch also participate in and contribute to national and international organizations and consortia to promote research on environmental risk factors and the germline and somatic contribution to cancer etiology. They conduct studies using tissue imaging, digital pathology, automated image analysis, and molecular/genomic analyses of tissues to comprehensively characterize features of normal, precursor and tumor tissues. Branch members and their collaborators develop and use computational tools to integrate and analyze high-dimensional data to link germline and environmental exposures to molecular features of cancer and precursor lesions, including somatic genomic signatures of risk factors, particularly those with high attributable risk.
This non R & D support services contract is essential for ITEB to conduct high-impact epidemiologic studies that integrate quantitative exposure assessment and molecular epidemiology to provide new insights into cancer etiology, chemical carcinogenesis, and mechanisms of action. The National Cancer Institute NCI/ITEB requires the assistance of an organization highly experienced in providing technical support for occupational and environmental epidemiologic studies, including support for exposure assessment and molecular components, and coordination of activities related to genome-wide association studies (GWAS); and in conducting and simultaneously managing concurrent, multiple, large (including international) epidemiologic investigations of cancer etiology.

The project will require a contractor to perform the following tasks:
Task 1: Initial Transition
Task 2: Study Initiation and Liaison
Task 3: Preparation of Study Materials and Procedures
Task 4: Subject Identification, Selection, and Tracing
Task 5: Interview and Abstracting Data Collection
Task 6: Specimen Collection, Processing, and Shipment
Task 7: Preparation
Task 8: Computer Programming and Data Processing
Task 9: Study Monitoring, Quality Control, and Reporting
Task 10: Final Transition:
The NCI seeks a continuation of services to be acquired through full and open competitive procedures under RFP #N02CP81000-87. It is anticipated that a cost-reimbursement, level of effort, type contract with a base period of nine (9) months, four (4) option periods of one (1) year each, and one (1) option period of three (3) months; may be awarded beginning on or about December 7, 2018.
The Government anticipates that one (1) contract will be awarded.
The RFP will be available electronically at a later date and may be accessed through the FedBizOpps website at www.fbo.gov. WE ENCOURAGE ALL RESPONSIBLE SOURCES, PARTICULARLY SMALL BUSINESSES, TO SUBMIT A PROPOSAL, WHICH WILL BE CONSIDERED BY THE AGENCY. This notice does not commit the Government to award a contract. No collect calls will be accepted. No facsimile or email transmissions will be accepted. IT IS THE OFFEROR'S RESPONSIBILITY TO MONITOR THE ABOVE MENTIONED SITE FOR THE RELEASE OF THE SOLICITATION AND ANY AMENDMENTS.
Contracting Office Address:
9609 Medical Center Drive
Bethesda, Maryland 20852

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Added: Jan 25, 2018 11:26 am Pre-Solicitation Notice: N02CP81000-87
Contracting Office Address
Department of Health and Human Services
National Institutes of Health (NIH)
National Cancer Institute (NCI)
Office of Acquisitions
9609 Medical Center Drive, Room 1E612, MSC 9705
Bethesda, MD 20892-9705

Note: This synopsis follows a Sources Sought notice that was released on November 20, 2017 under

HHS-NIH-NCI-SBSS-ETSB-1000-87
THIS IS A NOTICE OF INTENT, NOT A REQUEST FOR PROPOSAL. A SOLICITATION WILL BE ISSUED ON A LATER DATE.

Title: Integrative Epidemiological Studies

Description:
The National Cancer Institute (NCI), Integrative Tumor Epidemiology Branch (ITEB) advances the understanding of cancer etiology and progression through integrative analyses of environmental and germline risk factors with comprehensive data on histological and molecular profiling of tumors and their precursors, including somatic genomic analyses. The branch also develops methods to support this cutting-edge research.

ITEB employs molecular pathology, somatic and germline genomics, and epidemiology to identify environmental and germline risk factors for cancer. The ITEB research program includes case-control, cohort, family, and cross-sectional studies. Investigators in the branch also participate in and contribute to national and international organizations and consortia to promote research on environmental risk factors and the germline and somatic contribution to cancer etiology. They conduct studies using tissue imaging, digital pathology, automated image analysis, and molecular/genomic analyses of tissues to comprehensively characterize features of normal, precursor and tumor tissues. Branch members and their collaborators develop and use computational tools to integrate and analyze high-dimensional data to link germline and environmental exposures to molecular features of cancer and precursor lesions, including somatic genomic signatures of risk factors, particularly those with high attributable risk.

This non R&D support services contract is essential for ITEB to conduct high-impact epidemiologic studies that integrate quantitative exposure assessment and molecular epidemiology to provide new insights into cancer etiology, chemical carcinogenesis, and mechanisms of action. The National Cancer Institute NCI/ITEB requires the assistance of an organization highly experienced in providing technical support for occupational and environmental epidemiologic studies, including support for exposure assessment and molecular components, and coordination of activities related to genome-wide association studies (GWAS); and in conducting and simultaneously managing concurrent, multiple, large (including international) epidemiologic investigations of cancer etiology.

The project will require a contractor to perform the following tasks:

Task 1: Initial Transition
Task 2: Study Initiation and Liaison
Task 3: Preparation of Study Materials and Procedures
Task 4: Subject Identification, Selection, and Tracing
Task 5: Interview and Abstracting Data Collection
Task 6: Specimen Collection, Processing, and Shipment
Task 7: Preparation
Task 8: Computer Programming and Data Processing
Task 9: Study Monitoring, Quality Control, and Reporting
Task 10: Final Transition:

The NCI seeks a continuation of services to be acquired through full and open competitive procedures under RFP #N02CP81000-87. It is anticipated that a cost-reimbursement, level of effort, type contract with a base period of nine (9) months, four (4) option periods of one (1) year each, and one (1) option period of three (3) months; may be awarded beginning on or about December 7, 2018.

The Government anticipates that one (1) contract will be awarded.

The RFP will be available electronically at a later date and may be accessed through the FedBizOpps website at www.fbo.gov. WE ENCOURAGE ALL RESPONSIBLE SOURCES, PARTICULARLY SMALL BUSINESSES, TO SUBMIT A PROPOSAL, WHICH WILL BE CONSIDERED BY THE AGENCY. This notice does not commit the Government to award a contract. No collect calls will be accepted. No facsimile or email transmissions will be accepted. IT IS THE OFFEROR'S RESPONSIBILITY TO MONITOR THE ABOVE MENTIONED SITE FOR THE RELEASE OF THE SOLICITATION AND ANY AMENDMENTS.

Contracting Office Address:
9609 Medical Center Drive
Bethesda, Maryland 20852