Combined mass spectrometer and flash chromatography system

Closed Solicitation Posted

Solicitation number
75N95021Q00270
Agency
National Institute on Drug Abuse National Institutes of Health, Department of Health and Human Services
Responses due
Set-aside
Total Small Business

Opportunity facts

NAICS code
334516 Analytical Laboratory Instrument Manufacturing
PSC
6640 Laboratory Equipment And Supplies
Place of performance
Rockville, Maryland 20850, United States

Notice details come from SAM.gov. Updated .

Notice text

The purpose of this acquisition is to procure (1) one mass spectrometer and flash chromatography 
system for the real-time analysis of compounds designed and synthesized for the study and treatment 
of drug of abuse.

The requested chromatography system must satisfy the following requirements:
1.   Integrated ELSD component to detect compounds.
2.   Maximum dimensions Flash Chromatography: 26.8 x 14.1 x 17 inches (66 x 36 x 43cm); must 
operate in a fume hood.
3.   Maximum dimensions Mass Spectrometer: 26” x 11” x 22 inches (66 x 28 x 56cm);
4.   The small molecule mass spectrometer must easily interface with the flash chromatography 
system to add mass direct fractionation to the purification of novel compounds synthesized by 
chemists in the laboratory.
5.   The instrument must automatically switch between positive and negative ionization modes 
throughout the run and include a fluid interface module to remove sample and redirect t mass spec 
for analysis.
6.   The mass spec must include the following: full mass spectra data on any fraction tube, must 
automatically clean mass spec interface, must have multiple ionization settings, an option for 
multiple peak detection settings of an individual sample, capable of probe wash
and cone cleaning after each run, and single point of control of all mass spectrometer and 2
flash parameters.
7.   Users must have the ability to manually inject for pre-purification verification.
8.   ESI (electrospray ionization) is required for polar, ionizable, and acidic/basic compounds.
9.   The software must be user friendly and compatible between systems. The Signal to Noise ratio 
shall be increased, faster scan speed, and updated fluid interface decreasing pulsation during runs 
and improving signal trace.
10. Warranty against defects in material or workmanship. Instrument found to be defective during 
the warranty period will be repaired or replaced by the factory designated service center at no 
charge to the Government. A longer warranty is considered more desirable by the Government.
11. The selected contractor will also be required to provide installation and training. No 
government furnished equipment or supplies will be provided to the selected contractor for 
installation or training. Installation and training shall be coordinated with the technical 
end-user, who will be identified in the purchase order, and be conducted during normal
business hours (excluding Federal Holidays).
 

Attachments

Files attached to this notice, newest first
File Type Posted
RFQ No. 75N95021Q00270 & Attachments.pdf PDF

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