Combined mass spectrometer and flash chromatography system
Closed Solicitation Posted
- Solicitation number
- 75N95021Q00270
- Agency
- National Institute on Drug Abuse National Institutes of Health, Department of Health and Human Services
- Responses due
- Set-aside
- Total Small Business
Opportunity facts
- NAICS code
- 334516 Analytical Laboratory Instrument Manufacturing
- PSC
- 6640 Laboratory Equipment And Supplies
- Place of performance
- Rockville, Maryland 20850, United States
Notice details come from SAM.gov. Updated .
Notice text
The purpose of this acquisition is to procure (1) one mass spectrometer and flash chromatography
system for the real-time analysis of compounds designed and synthesized for the study and treatment
of drug of abuse.
The requested chromatography system must satisfy the following requirements:
1. Integrated ELSD component to detect compounds.
2. Maximum dimensions Flash Chromatography: 26.8 x 14.1 x 17 inches (66 x 36 x 43cm); must
operate in a fume hood.
3. Maximum dimensions Mass Spectrometer: 26” x 11” x 22 inches (66 x 28 x 56cm);
4. The small molecule mass spectrometer must easily interface with the flash chromatography
system to add mass direct fractionation to the purification of novel compounds synthesized by
chemists in the laboratory.
5. The instrument must automatically switch between positive and negative ionization modes
throughout the run and include a fluid interface module to remove sample and redirect t mass spec
for analysis.
6. The mass spec must include the following: full mass spectra data on any fraction tube, must
automatically clean mass spec interface, must have multiple ionization settings, an option for
multiple peak detection settings of an individual sample, capable of probe wash
and cone cleaning after each run, and single point of control of all mass spectrometer and 2
flash parameters.
7. Users must have the ability to manually inject for pre-purification verification.
8. ESI (electrospray ionization) is required for polar, ionizable, and acidic/basic compounds.
9. The software must be user friendly and compatible between systems. The Signal to Noise ratio
shall be increased, faster scan speed, and updated fluid interface decreasing pulsation during runs
and improving signal trace.
10. Warranty against defects in material or workmanship. Instrument found to be defective during
the warranty period will be repaired or replaced by the factory designated service center at no
charge to the Government. A longer warranty is considered more desirable by the Government.
11. The selected contractor will also be required to provide installation and training. No
government furnished equipment or supplies will be provided to the selected contractor for
installation or training. Installation and training shall be coordinated with the technical
end-user, who will be identified in the purchase order, and be conducted during normal
business hours (excluding Federal Holidays).
Attachments
| File | Type | Posted |
|---|---|---|
| RFQ No. 75N95021Q00270 & Attachments.pdf |
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