Chromium Single Cell Controller and Kits

This notice is a combined synopsis/solicitation for commercial items using Simplified Acquisition Procedures. This acquisition will be made in accordance with the format in Federal Acquisition Regulation (FAR) Subpart 12.6 "Streamlined Procedures for Evaluation and Solicitation for Commercial Items," as applicable, and as supplemented with additional information included in this notice. This announcement constitutes the only solicitation (a written solicitation will not be issued) and quotes are being requested. The Solicitation number is RFQ-RML-C-1917689 and the solicitation is issued as a Request for Quotes (RFQ).

This acquisition will be processed under FAR Part 13 Simplified Acquisition Procedures (SAP). The solicitation documents and incorporated provisions and clauses are those in effect through Federal Acquisition Circular FAC 2005-99_6-15-18.pdf as of (07-03-18).

The North American Industry Classification System (NAICS) code for this procurement is 334516; Analytical Laboratory Instrument Manufacturing, with a small business size standard of 1000 employees. The small business set aside is dissolved for this requirement.

The National Institute of Allergy and Infectious Diseases (NIAID) has a requirement for 10X Genomics, Brand name only:

Quantity of 1 Part # 120263 Chromium Single Cell Controller & Accessory Kit w/12 Mo. Warranty
Quantity of 1 Part # 120262 Chromium i7 Multiplex Kit, 96 reactions
Quantity of 1 Part # 1000009 Chromium Single Cell A Chip Kit, 16 rxns,
Quantity of 1 Part # 120267 Chromium Single Cell 3' Library and Gel Bead Kit v2, 4 rxns

Must quote shipping costs and warranty

Place of Performance: NIAID NIH ROCKY MOUNTAIN LAB, 903 S 4th St., Hamilton, MT 59840
FOB: Destination

The government intends to award a firm fixed price purchase order to the responsible contractor as a result of this RFQ that will include the terms and conditions set forth herein. The award will be based on the following; capability to meet the requirements, delivery, past performance, price and the overall best value to the government.

The following FAR provisions apply to this acquisition:

FAR 52.212-1 Instructions to Offerors Commercial Items (Jan 2017)

FAR 52.212-3 Offerors Representations and Certifications - Commercial Items (Nov 2017)

Offerors must complete annual representations and certifications on-line at http://www.sam.gov/ in accordance with FAR 52.212-3 Offerors Representations and Certifications- Commercial Items
(Please ensure 52.209-2 -- Prohibition on Contracting with Inverted Domestic Corporations--Representation. (Nov 2015) is updated in your SAM record)
FAR 52.203-18 Prohibition on Contracting with Entities that Require Certain Internal Confidentiality Agreements - (Jan 2017)

The following FAR contract clauses apply to this acquisition:

FAR 52-212-4 Contract Terms and Conditions Commercial Items (Jan 2017)
FAR 52-212.5 Contract Terms and Conditions Required to Implement Statutes or Executive Orders Commercial Items (Jan 2018)
*The applicable subparagraphs of FAR52.212-5 are included in the attachment to this posting.
FAR 52.203-19 Prohibition on Contracting with Entities that Require Certain Internal Confidentiality Agreements (Jan 2017)
FAR 52.232-40 Providing Accelerated Payments to Small Business Subcontractors (Dec 2013)
FAR 52.204-13 System for Award Management Maintenance (Oct 2016)
FAR 52.204-19 Incorporation by Reference of Representations and Certifications (Dec 2014)

HHSAR 352.222-70, Contractor Cooperation in Equal Employment Opportunity Investigations (Dec 2015)

By submission of an offer, the offeror acknowledges the requirement that a prospective awardee shall be registered in the System for Award Management (SAM) database prior to award, during performance, and through final payment of any contract, basic agreement, basic ordering agreement, or blanket purchasing agreement resulting from this solicitation (www.sam.gov).

Copies of the above-referenced provisions and clauses are available from http://farsite.hill.af.mil/reghtml/regs/far2afmcfars/fardfars/far/52_000.htm

Justification for Other than Full and Open Competition
at or Below the Simplified Acquisition Threshold
BRAND NAME
Project Title: ChromiumTM Single Cell Controller

I. Identification of the agency and contracting activity
NIH Rocky Mountain Laboratory
903 S 4th Street
Hamilton, MT 59840

A. Project Background
The Rocky Mountain Laboratory (RML) Laboratory of Bacteriology (LB) Immunity to Pulmonary Pathogens Section elucidates the mechanism by which highly virulent pathogens, including the intracellular bacterium Francisella tularensis, evades and suppresses host immune responses to cause disease. This works utilizes in vitro cell culture of primary human and murine cells as well as an in vivo mouse model to define the molecular mechanisms by which F. tularensis and other pathogens manipulate the host immune system to cause disease and death.

B. Project Description
The Immunity to Pulmonary Pathogens Section performs tissue culture experiments to identify the mechanism by which pathogens manipulate host cell processes to cause disease. The use of RNA sequencing technologies is a powerful tool to understand the changes in gene expression over time, following infection. Currently, this is done in one reaction containing mixed cell populations. This provides information on gene expression in bulk cells, but does not reveal how individual cells respond. The 10X Chromium Single Cell Controller will allow us to analyze gene expression in individual cells including their relative infection status. This is a powerful technology that will greatly improve our understanding of the interface of pathogen, infected cell and uninfected by-stander cells.

II. Identification of the statutory authority permitting other than full and open competition (SELECT ONE)
☒ 41 USC 3304(a)(1) and FAR 13.106-1(b): Only one responsible source / Brand Name
☐ FAR Part 8.405-6: Federal Supply Schedule (FSS), limited competition / Brand Name

A. Description of the supplies/services to be purchased:

1. Quantity of 1 Chromium i7 Multiplex Kit, 96 rxns 120262
2. Quantity of 1 Chromium Single Cell 3' Library and Gel Bead Kit v2, 4 rxns 120267
3. Quantity of 1 Chromium Single Cell A Chip Kit, 16 rxns 1000009
4. Quantity of 1 Chromium Single Cell Controller and Accessory Kit 120263

Manufacturer: 10x Genomics, 7068 Koll Center Parkway, Suite 401, Pleasanton CA 94566

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