6640--Leica LMD7 Microscope System

Regional Procurement Office (RPO) - East intends to negotiate on a sole source basis with Leica Microsystems, Inc., 1700 Leider Lane, Buffalo Grove, IL 60089 to purchase Leica Laser Capture Microdissection System LMD7 microscope system for the Roudebush VA Medical Center, Indianapolis. The equipment requested will be used to advance ongoing translational research programs at the Research Department at the facility. The following equipment will be purchased:

ITEM INFORMATION

ITEM NUMBER

DESCRIPTION OF SUPPLIES/SERVICES

QUANTITY

UNIT

0001

LMD7 with fluorescence and scanning stage package consisting of:

11888875 LMD7 (LED, mot.Z)

11890017 CTR6 LED

11888887 Top LMD6/7, 5fold, Fluo, 7xM25, mot. 11504115 External light source EL 6000

11504117 Lightguide coupler 1"

11504116 Liquid Light Guide for EL6000, 2m 11513911 Filter system LMDBGR

11888830 Condenser DIC for LMD

11505234 Condenser head 0.55 S28

11888449 LMD Scanning stage

11888425 Advanced XYZmodule LX

11505180 Smart Move for DM/DMI Series 11518148 Obj. UVI 2.5x/0.07 Microdissection 11518145 Obj. UVI 6.3x/0.13 Microdissection 11518147 Obj. UVI 10x/0.25 Microdissection 11506208 Obj. HC PL FL L 40x/0.60 CORR XT 11505216 Patho diffusor plate for 1.255x object. 11600271 FullHD LCDMonitor 24", 1920x1080 11600220 Keyboard US, USB Hub

11501478 LMD CC7000 camera

11541544 CMount HC 0.55x

11505161 Tube adapter including 1 docu. port 11505508 Optics Cleaning Kit

11600291 Antivibration Plate for LMD systems

STOCK NUMBER: 11510040

1.00

EA

0002

Service Installation

STOCK NUMBER: 9I_CM_CLASS_H

1.00

EA

The isolation of pure targeted cells is an important and essential step for the molecular analysis of cells involved in the progression of liver diseases. Laser capture microdissection (LCM) is powerful in obtaining a pure targeted cell subgroup, or even a single cell, quickly and precisely under the microscope, successfully tackling the problem of liver tissue heterogeneity in molecular analysis. The LMD7 equipment will be used to study intracellular signaling and protein interactions in single human cell stage under pathological conditions of human liver and other diseases that lead to significant mortality and morbidity in the Veteran population.

Salient Characteristics:

Contact free, gravity based collection method

Laser movement via optics (not mechanics)

Adjustable and flexible laser technology (adjustable and flexible)

Maximal flexibility (collection devices, consumables)

Special optics for laser micro dissection

Simultaneous cutting within fluorescence

Automated recognition of cells

This notice of intent is not a request for competitive proposals. Any responsible sources who wish to identify their interest and capability to provide this equipment or equipment that is compatible must notify this Contracting Specialist at millicent.covert@va.gov by Friday, April 10, 2020, NLT 11:59 AM EST. Telephone responses will not be accepted. Upon receipt of the interested parties' notification, the Contracting Officer will determine whether to conduct a competitive procurement or proceed with sole source negotiations.