6640--High Parameter Flow Cytometer

Regional Procurement Office (RPO) - East intends to negotiate on a sole source basis with Becton, Dickinson, and Company to purchase the BD FACSSymphony A3 Cell Analyzer for the Research Service at the VA Ann Arbor Healthcare System. The following equipment and configuration will be purchased:

ITEM INFORMATION

Item Number

Description

Quantity

Unit of Measure

0001

SYMPHONY A3 SORP

1

EA

0002

SO Symphony A3 Base Components

1

EA

0003

Laser Coherent OBIS 488-100 LS SORP

1

EA

0004

SSC Detector Decagon

1

EA

0005

BB515 Detector BB515 (505LP; 515/20)

1

EA

0006

BB630 Detector BB630 (600LP; 610/20)

1

EA

0007

BB700 Detector BB700 (690LP; 710/50)

1

EA

0008

BB790 Detector BB790 (770LP; 780/60)

1

EA

0009

LASER OBIS 637-140 LX SORP

1

EA

0010

Detector Decagon w/o SSC

1

EA

0011

APC Detector APC (650LP; 670/30)

1

EA

0012

Alexa 700 Detector Alexa 700: 690LP; 710/50

1

EA

0013

APC Cy7 Detector APC Cy7 (750LP; 780/60)

1

EA

0014

LASER VIOLET COHERENT OBIS 405-100 LX

1

EA

0015

Detector Decagon w/o SSC

1

EA

0016

BV421 Detector BV421 (410LP;431/28)

1

EA

0017

BV480 Detector BV480 (450LP; 470/14)

1

EA

0018

BV605 Detector BV605 (600LP; 610/20)

1

EA

0019

BV650 Detector BV650 (635LP; 670/30)

1

EA

0020

BV711 Detector BV711 (690LP; 710/50)

1

EA

0021

BV786 Detector BV786 (750LP; 780/60)

1

EA

0022

LASER SYSTEM UV-G4 355-20 W/BE SORP

1

EA

0023

UV Detector Decagon w/o SSC

1

EA

0024

BUV396 Detector BUV396 (378/29)

1

EA

0025

BUV496 Detector BUV496 (450LP; 515/30)

1

EA

0026

BUV563 Detector BUV563 (550LP; 586/15)

1

EA

0027

BUV661 Detector BUV661 (635LP; 670/30)

1

EA

0028

BUV737 Detector BUV737 (690LP; 740/35)

1

EA

0029

BUV805 Detector BUV805 (770LP; 820/60)

1

EA

0030

LASER COHERENT OBIS 561-100 LS SORP

1

EA

0031

Detector Decagon w/o SSC

1

EA

0032

PE w/561 Detector PE (570LP; 586/15)

1

EA

0033

PE CF594 Detector PE CF594: 600LP; 610/20)

1

EA

0034

PE Cy5 Detector PE Cy5: (650LP; 670/30)

1

EA

0035

PE Cy7 Detector PE Cy7: (750LP; 780/60)

1

EA

0036

BD FACSflow Sheath Fluid 20L

1

EA

0037

BD CST Beads Kit 150 Tests

1

EA

0038

BD FACS Sheath Solution With Surfactant

1

EA

0039

X-Optic 450/50 (410LP; 450/50)

1

EA

0040

X-Optic 515/30 (450LP; 515/30)

1

EA

0041

Computer Bundle Z2MiniG5 LSR Fortessa

1

EA

0042

NEC 19In LCD Monitor

2

EA

0043

Coherent Connection with Integration Kit

1

EA

0044

Option FACSFlow Supply Sys LSRFortessa

1

EA

0045

LSRfortessa Instrument Table

1

EA

0046

Svc Cont FACSymphony A3

1

EA

0047

Svc Cont OBIS 488-100 LS Blue Lsr

1

EA

0048

Svc Cont OBIS 637-140 LX Red Lsr

1

EA

0049

Svc Cont OBIS 405-100 LX Violet Lsr

1

EA

0050

Svc Cont G4 355-20 w/BE UV Lsr

1

EA

0051

Svc Cont OBIS 561-100 LS Y/G Laser

1

EA

0052

Svc Cont FACS Flow Supply System

1

EA

0053

HPS Fluorochrome Evaluation Kit

1

EA

0054

HPS Prototype Fluorochrome Eval Kit

1

EA

0055

HIGH PARAMETER IMMUNOLOGY PANEL

1

EA

Multiple VA-funded research projects at the Ann Arbor facility are currently supported by a cell analyzer (LSRII flow cytometer) that was originally purchased from BD over 15 years ago. The instrument and the information it provides are central to the research projects of multiple VA investigators on a daily basis, which has led to the generation of publications, grants, and high-quality research data. BD no longer provides support for the LSRII flow cytometer. Without the regular maintenance and repairs that BD provided, the LSRII is becoming inoperable. BD offers a replacement under its new line of FACSSymphony flow cytometers. It is necessary to continue with BD instruments for the following reasons:

Flow cytometers are highly specialized machines with unique laser configurations and filter sets to detect fluorochromes that are excited and emit a signal at a specified wavelength. BD s replacement cytometer will have the same laser configuration of the LSR II. The same fluorescent panel that investigators designed for use in their experiments on the LSRII will also work in the FACS Symphony. Importantly, this means that investigators who have collected data on the LSR II will not have to repeat experiments and will not be in jeopardy of losing valuable data. Switching to a cell analyzer from a new vendor would lead to delays in the completion of experiments and additional costs and waste of valuable resources, as experiments would need to be validated and repeated on the new equipment.

Trade in of LSRII can only be done with BD. BD is the only company capable of providing the replacement equipment needed without the Veteran s Health Administration experiencing substantial duplication of cost, resources, and time, that could not be expected to be recovered through competition.

This notice of intent is not a request for competitive proposals. Any responsible sources who wish to identify their interest and capability to provide this equipment or equipment that is compatible must notify this Contracting Officer at Millicent.Covert@va.gov NLT Friday, December 2, 2022 by 11:59 AM EST. Telephone responses will not be accepted. Upon receipt of the interested parties' notification, the Contracting Officer will determine whether to conduct a competitive procurement or proceed with sole source negotiations.