SOW Draft.pdf

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Statement of Work (SOW) Nuclear Magnetic Resonance Spectrometer

For Honey Adulteration and Country of Origin Testing

1.0. BACKGROUND

This statement of work (SOW) defines the requirements for the Government to obtain Nuclear Magnetic Resonance (NMR) equipment. In accordance with Senate Report 116-125 (DHS Security Appropriations Bill, 2020); the U.S. Customs and Border Protection was directed to purchase and use Nuclear Magnetic Resonance (NMR) testing for the purpose of identifying honey marked with an inaccurate country of origin or adulterated with substances that could undermine the product’s consumer reputation.

As such, U.S. Customs and Border Protection Field Laboratory seeks to purchase a 400 MHz Fourier Transform Nuclear Magnetic Resonance Spectrometer (NMR). CBP scientists will use NMR to analyze honey and potentially other food products imported into the United States as required by the Harmonized Tariff Schedule of the United States or the Code of Federal Regulations, for enforcing appropriate duty collection and antidumping and countervailing duty orders.

2.0. SCOPE

This is a project to purchase and install the 400 MHz Food Screener Platform specifically designed for food testing. This Commercial Off the Shelf (COTS) instrument comprises all components necessary for standardization of the sample matrix to minimize differences between unknown and database (reference) spectra. This instrument will aid CBP in its mission to facilitate legitimate international trade while protecting the Homeland from counterfeit and mislabeled materials. Identifying the nature of the honey crossing our borders will help prevent misclassification or fraud in the correct application of duties and fines.

3.0. APPLICABLE DOCUMENTS

Commercial standards shall be used wherever practicable.

4.0. SPECIFIC TASK

The Contractor shall provide all equipment, installation, training and technical support necessary to perform the specified work requirement. The installed instrument system, software, and database applications shall be new, commercially available, and in commercial production as of the closing date of this announcement. The complete installed instrument system in the New York Laboratory shall meet the entire main and sub-system manufacturer’s published performance specifications as installed in our laboratory on our site.

4.1. Instrument requirements:

The instrument system containing all listed sub-systems and major components shall be provided as part of the complete instrument system and each shall meet their individually described detailed technical and performance specifications. The instrument system and sub-systems will be purchased from a single vendor.

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Sample preparation equipment and supplies shall be provided, sufficient for preparing honey samples to a standardized state, identical to that in which database sample spectra were collected. Sufficient supplies, e.g. buffers and references solutions, for 1000 honey samples will be included. The system, in conjunction with the remote honey profile database searching and included statistical reporting software, must, at a minimum, be capable of the following tasks: (1) measuring the one-dimensional spectra of properly prepared honey samples; (2) transmitting that spectral information to a remote honey profile database; and (3) returning a statistically significant match to both the presence of adulterants and the region or country of origin of the honey sample. In addition, the capability must exist for local reference materials to be tested, stored, and queried, and return results of a similar nature to the remote database. The laboratory originally conducting the validation of the method used by the statistical profiling database and software must be accredited to ISO 17025 by an appropriate accreditation agency. Method validation information and the accreditation certificate must be provided.

400 MHz NMR magnet, console, probes, etc. shall meet the following specifications:

Acquisition System

System Clock 80 MHz, synchronous within 12.5 ns on all channels

Transceiver(s)

Two channels RF bandwidth: 5 – 1200 MHz for transmit/receive Timing resolution of 12.5 ns ADC: 240 MSPS @ 16-bits

DAC: 960 MSPS

Intermediate Freq for transmit/receive: 1852 MHz Sequencer waveform RAM: 1 GB Spectral Width: 7.5 MHz Effective range: >17 Bit (5 MHz) / >19 Bit (1 MHz) / >23 Bit (6 kHz)

Gradient Amplifier

Pulsed field gradient up to 10A On-axis (Z)

Magnet

Field 9.4 Tesla Strayfield 0.5m per 1.0m axial Helium hold time > 300 days Cryogen level sensors

Helium (with alarm) and Nitrogen

Vibration damping Gimbal type for isolating both vertical and horizontal directions

Shim board (2) Current sources Min 20 @ 20-bit, ± 1A ea.

2 Ch RF Amplifier Power (min 100) 100W RF peak @ 180 – 600 MHz (max 25W

CW)

Power (min 500) 500W RF peak @ 15 – 500 MHz (max 50W

CW)

1H GaAs Preamp Noise figure 1 dB RF capability 4kW max peak

19F GaAs Preamp Noise figure 1.4 dB

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RF capability 500W max peak 1H stop filter Built-in

2H GaAs Preamp Noise figure 1.4 dB RF capability 500W max peak 2H lock/observe Built-in

2H Lock transceiver Gradient shimming and locking for deuterated solvents

Variable Temperature

Sensor NLT 5 mK Gas flow <3000 lph with mass flow regulation Max temp 600 °C

Probe 1

Lock 2H BB range 19F - 199Hg and 17O - 109Ag VT range -150 °C to +150 °C Z-grad 5 G/A*cm Automatic probe recognition Gas compensation

Air

Tune & Match Automated

Probe 2

Lock 2H

BB ranges

200MHz: BB range 31P-97Mo 250MHz: BB range 31P-97Mo 300MHz: BB range 31P-97Mo 400MHz: BB range 31P-109Ag

VT range -150 °C to +150 °C Z-grad 5 G/A*cm Automatic probe recognition Gas compensation

Air

Tune & Match Automated

The following miscellaneous hardware and software components are to be included:

Uninterruptible power supply

6kVA 115FV/20A

Compressor Compressed air at 4 CFM/120 psi (max) Sample Changer 60 positions Spinners 59, standard bore Helium transfer line As appropriate for instrument Nitrogen transfer line

As appropriate for instrument

Automated pH unit pH adjustment in the sub-μl range Touch panel operation Shaker (300 – 3000 rpm) 1 & 3 point pH calibration Two probes

Acquisition and data Windows 10 Professional 64-bit

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Sample training computer

Computer and monitor for barcode assignment and sample tracking

Software

Spectra acquisition and processing, including automated acquisition Structure analysis software Database storage, retrieval, and searching Database of food compounds at pH 3 (including 1H, JRES, COSY, TOCSY, HSQC, HMBC, and 13C spectra) Barcode-based sample tracking

Honey Profiling module

Honey profiling method and spectral fingerprint searching

Barcode printer For sample tracking; barcodes appropriate for NMR tubes

The following consumable supplies are to be included:

NMR Tubes Reference tubes for calibration (as necessary) 5 mm tubes (min 200)

Vials 1.8 mL, for pH adjustment, suitable for pH (min 1000 samples) pH probe regeneration solution

Sufficient quantity for 5000 cleaning steps pH reference material pH 3.1, or as appropriate for reference database; sufficient for 1000 samples

Food Buffer Buffer for honey sample preparation; sufficient for 1000 samples Barcode labels For barcode printer; sufficient for 1000 samples Extra printer ribbon For barcode printer

4.2. Setup/installation and training

The vendor shall provide installation qualification and operation qualification (IQ/OQ) and any other pertinent certification at the time of installation. Inside delivery and set-up of all purchased equipment, supplies, hardware, and software is required. The vendor shall provide software and firmware upgrades free of charge for a minimum of three years from the date of installation of the instrument.

Software and firmware updates shall be applied to the instrument without the need for an internet connection.

The installation shall include:

Installation Rigging and any other rental equipment for magnet installation All cryogens for startup (liquid helium and nitrogen) Installation service and validation

Instrument revalidation

1-yr revalidation and recalibration of instrument and components, including renewal of shim matrices, performance maintenance for sample changer, and updates to statistical models

Site survey Pre-installation site visit to validate site of installation

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An in-house training session by a qualified trainer, directly employed by the vendor, is required for the instrument upon installation. The training session will occur at the Laboratory in New Jersey at the address shown below. The training session shall provide familiarize at least three staff members with the software, basic operation, set-up of user accounts, interpretation of data, other software capabilities, and basic hardware maintenance (including cryogen addition), and troubleshooting. Travel/per diem fees for installation/training specialist shall be included. Training shall include both honey-module specific and general-purpose NMR topics. The training session shall not occur later than 30 calendar days after equipment installation is complete.

4.3. Warranty and updates

The vendor shall provide warranty on the instrument for a minimum of three years from the date of installation of the instrument on all hardware and software purchased. The warranty shall include all parts (exclusive of those parts with published life expectancies of less than three years), labor, and travel/per diem expenses. The warranty shall include performance of preventative maintenance as recommended by the manufacturer. On-site repair and maintenance by a qualified service engineer will be available within five business days of a service call.

Since the laboratory intends to use the instruments for approximately ten years it is the expectation of the laboratory that manufacturer provided service and spare parts will be readily available for purchase for the next ten years. An affirmative statement to this effect is required. On site, proof of satisfactory operation within the manufacturer’s specifications shall be provided prior to acceptance of the instruments.

4.4. Program management: N/A

4.5. Testing: N/A

5.0. DELIVERY: The Vendor shall ship the equipment, including applicable, associated software, to the address outlined in Section 5.2.2“Shipping Address.”

5.1. Documentation: The Vendor shall be responsible for issuing required documents as noted in section 5.2.3, “Data.”

5.2. Deliverables and schedule

5.2.1. Equipment

The Vendor shall deliver the instrument package comprising the hardware and software stated in the associated quote. Delivery shall be coordinated with the New York Laboratory to ensure that someone is present to accept the delivery. Delivery of equipment must occur between 9:00 AM and 4:00 PM Local Time (to accommodate loading dock availability). Delivery must take place at street level, as no elevated loading dock is available.

5.2.2. Shipping Address:

US Customs and Border Protection New York Laboratory Attn: Matthew Birck, PhD

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1100 Raymond Blvd., Suite 550 Newark, NJ 07102

5.2.3. Data

As referenced in section 5.1, “Documentation,” the Vendor shall provide copies of the documents listed below. One copy of the data shall be delivered in paper form and one copy in electronic form.

The electronic form shall be in MS Word format or Adobe Acrobat PDF.

1) Completed invoicing

2) If applicable, the following items also are required for delivery:

a. Any associated software license/key documentation and (or) software download link(s).

b. The document(s) are deliverables under the contract and shall be delivered to Matthew Birck no later than thirty days after shipping date.

6.0. GOVERNMENT FURNISHED EQUIPMENT AND INFORMATION: The Government does not anticipate providing any GFE or GFI.

7.0. PLACE OF PERFORMANCE: The place of performance shall be at the contractor’s facility

(see shipping address 5.2.2).

8.0. PERIOD OF PERFORMANCE:

The period of performance shall be the date of the contract acceptance by the Government until delivery of the specified instrument has been completed, tested, and accepted by CBP.

Note that “accepted by CBP” is not accomplished until all aspects of the SOW/contract, including vendor setup, testing, and verification of the device and all training (when applicable) has been completed. Simply delivering a device does not mean an invoice will be approved for payment. The Government reserves the right to reject any invoice until all deliverables have been meet/accepted to the government’s satisfaction.

9.0. SECURITY: The security classification for this equipment is “Law Enforcement Sensitive”

(LES).

10.0. SPECIAL CONSIDERATIONS: N/A

10.1. Changes to sow

No changes to this SOW or cost increases shall be incurred without written prior approval of the Contracting Officer as coordinated by the Contracting Officer Representative (COR). Any changes or cost increases will not take effect until the Contracting Officer executes a written modification.

10.2. TRAVEL: Travel is not required to support the tasks identified in this SOW.

11.0. POINT OF CONTACT

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All contract questions and concerns shall be directed to the point of contact as designated below. The Contracting Officer is the only individual with the authority to amend this contract.

Point of Contact:

Starla Van Winkle Contract Specialist Starla.r.vanwinkle@cbp.dhs.gov