Minimum_specifications_for_detection_system_1922674.docx

Minimum specifications

· Eight parallel, independent channels for maximum speed and assay flexibility

· Versatility to detect biomolecules from small molecules up to mammalian cells

· High-quality kinetic screening and affinity characterization of biomolecules. Measurement of long dissociation times possible for high affinity binding pairs.

· Large quantitation dynamic range Simple one-step assay to measure 25 ng/mL to 2 mg/mL of IgG concentration in crude matrices in as little as two minutes per samples or 32 minutes for a whole 96-well plate

· High sensitivity to sub-ng/mL levels possible with 2-step and 3-step assay formats, allowing automated measurement of contaminants such as host cell proteins and residual protein A

· Microfluidics-free dip and read format with biosensor regeneration, and re-racking option

· Non-destructive sampling allows full sample recovery. Microplate evaporation cover further minimizes losses in sample volume, allowing post-analysis recovery of precious samples after a 12-hour run.

· Up to 12 hours of unattended run time. Increased throughput for screening and characterization purposes.

· Sample plate cooling for temperature-sensitive proteins and for thermodynamic analysis to determine binding rate constants at multiple temperatures to calculate thermodynamic parameters.

· Software enables multi-experiment analysis, customized reports