Purchase Description-75N95023Q00442.pdf

Version 11-30-2016-1 FAR Part 11—Describing Agency Needs

PURCHASE DESCRIPTION

1. Statement of Need and Purpose: This acquisition is necessary for automation of the culture techniques used in the iPSC Neurodegenerative Diseases Initiative (INDI) Project within the new Center for Alzheimer’s Disease and Related Dementias.

2. Background Information and Objective: imaging technology improves to capture The Government is working to create a national resource of isogenic sets of Alzheimer’s Disease and Related Dementias mutated iPSC lines, complimented by foundational phenotypic datasets from differentiated disease-relevant cells derived from these lines.

This resource will substantially accelerate the pace of mechanistic discovery regarding how ADRD mutations cause disease. An automated liquid dispensing device is needed to create a high through put workflow for processing tissue culture cells to enable genetically engineered iPSCs.

3. Generic Name of Product: Automated liquid dispensing device

4. Purchase Description:

Description: Quantity Cat no:

Mantis V3.3 with Integrated RFID, Chip Changer - 6 Chip capacity and Mantis Controlling Software Instrument License

1.00 233095

Mantis Continuous Flow Option 1.00 MCF

One LC3 Base Unit including RFID Reader 1.00 290595_A

Mantis Remote User Training 1.00 360787

Mantis Chip - Silicone, HV (1uL & 5uL), RFID, PI. Pack of 12 1.00 233648

Mantis Chip - Silicone, LV (0.1uL & 0.5uL), RFID, PI. Pack of 6 1.00 233581

PCR Plate Adapter with wide conical pins for automated plate handling 1.00 232400

Mantis Nozzle Kit - Silicone (Includes 0.1, 0.2, 0.3, 0.4, 0.6mm ID, 2 each) 1.00 233036

Mantis Silicone Input Tube Holder for 15mL or 50mL source tubes 1.00 233858B

One Right Side LC3 Locating Plate for use in the set up of one LC3 unit attached to a Mantis. Includes a waste station adapter.

1.00 290604

Mantis Chip - Silicone, Continuous Flow (CF), RFID, PI. Pack of 6 1.00 233127 Mantis CF Cap - Nalgene Bottle, Silicone Harness, pack of 6. 1.00 233125

Shipping 1.00 NA

Salient characteristics All deliverables required under this contract shall be packaged, marked and shipped in accordance with Government specifications. At a minimum, all deliverables shall be marked with the contract number and Contractor name. The Contractor shall guarantee that all required materials shall be delivered in immediate

Version 11-30-2016-1 FAR Part 11—Describing Agency Needs usable and acceptable condition.

Vendor must be able to provide these specifications:

Instrument must have a footprint no larger than (6.9” x 8.5” x 9.3”)

Instrument must include a microdiaphragm pump technology to provide non-contact delivery of desired volumes of liquids into wells of SBS based 96, 384 and 1536 well microplates, as well as deep well blocks and vials.

Instrument must allow for low volume dispensing from 100 nL and up

Instrument must allow for low dead volume at 6uL

Instrument must allow for fast dispensing of high volumes with a continuous flow option.

Instrument must allow for dispensing reagents, cells (mammalian and bacterial) and beads (magnetic and non-magnetic)

5. Delivery Date: Delivery date of 3 months after receipt of order (ARO).

6. Period of Performance: Manufacturer warranty for one calendar year beginning date of receipt.