5.5000270_PHERAstar_SSJ.pdf

Revised10/31/2016

FAR Subpart 13.106-1(b)

SOLE-SINGLE SOURCE (including Brand-Name) JUSTIFICATION

“Source Selection Information – see FAR 2.101 and 3.104”

1. Identification of the Agency and Contracting Activity.

a. Federal Agency and Contracting Activity.

Department of Health and Human Services (DHHS) National Institutes of Health (NIH) National Institute on Drug Abuse (NIDA)

b. Sponsoring Organization.

• National Center for Advancing Translational Sciences (NCATS)

• Division of Preclinical Innovation (DPI)

c. Project Officer Information.

• Project Officer name- Sam Michael

• Mailing address- 9800 Medical Center Drive, Building B, Rockville, MD 20850

• E-mail address- michaelsg@mail.nih.gov

• Telephone number- 301-827-7796

2. Project Description.

a. Project Title. Acqusition of four BMG PHERAstar FSX multimodal microplate readers

b. Description of the Item or Service.

NCATS seeks to purchase four BMG PHERAstar FSX multimodal plate readers for integration on a variety of fully automated robotic platforms. The robotic systems currently feature key elements for an automated screen (reagent dispenser, incubators, pintool, and robotic arms), but lack a PHERAstar plate reader. NCATS previously acquired three PHERAstar plate readers for offline laboratory use and having additional readers to be integrated onto automated robotic platforms are necessary such that there is continuity for scientific experiments which have been validated on an offline instrument. The addition of the PHERAstar plate readers will make it possible for assays to be run in a fully automated fashion which is critical towards NCATS achieving its scientific mission.

The PHERAstar FSX multimodal plate readers are commercially available items that are customized with options to fit the specific laboratory needs. Each of the four specific units required will include features and options as listed below:

mailto:michaelsg@mail.nih.gov

0902-101 STACKER III Discount for Buying multiple Stackers 1500-MAG-9001 Plate Magazine for 900 Stacker in place of one with 50 plate magazine 1300-540 Barcode Readers Free with TRF Laser 0472-101A PHERAstar FSX Basic 1100-472-401 Absorbance FS Spectrometer 1100-472-501 High-End TRF/HTRF 1100-472-502 TR-FRET Laser 1100-472-601 HTS AlphaScreen Laser 1300-500 Manufacturer's Warranty 1300-501 Control and Evaluation Software 1300-502 Installation and Training 1300-530 Standard Incubation 1300-560 Multi-PMT Measurement System 1300-570 Simultaneous Dual Emission 1400-G2M-FI-485-520 Optic Module Comes with base instrument 1400-G3M-AS-680-570 Optic Module 1400-G3M-AS-680-615 Optic Module

1400-G3M-FI-410-460-

Optic Module GeneBLAzer - Free with this purchase

1400-G3M-TRF-337-665-

Optic Module

2000-201 Standard Freight Shipping & Handling Shipping for 4 PHERAstars and Stackers

3. Market Research Market Research was conducted in accordance with FAR Part 10. A small business sources sought notice was published on FBO on March 9, 2018, advertising the detailed specifications required in this acquisition. No capability statements demonstrated an ability to meet the stated requirements. In addition, the requiring activity has tested other plate readers and has determined that they do not provide acceptable performance.

4. Acquisition Type.

This acquisition exceeds $150,000 and is not expected to exceed $7 million, and is conducted in accordance with FAR Subpart 13.5—Simplified Procedures for Certain Commercial Items.

5. Acquisition Authority. This acquisition is conducted under the authority of the Federal Acquisition Regulations (FAR) Subpart 13.106-1(b)(2). Soliciting from a single source, for purchases exceeding the simplified acquisition threshold, must be justified in writing and approved at the levels specified at FAR 13.501(a)(2).

6. Justification Rationale.

Only one source is available:

I hereby determine that the PHERAstar FSX plate readers listed herein are available from only one source, and competition is precluded for the reasons indicated below.

There are no substitutes available, as indicated by the market research above.

The acquisition is for a multimodal plate reader that offers the most advanced features that are compatible to NCATS current robotic system. Once integrated onto RNAi’s robotic system, the PHERAstar FSX will be able to read plates using many assay technologies including fluorescence intensity (FI), fluorescence polarization (FP), alpha screen, luminescence, absorbance and time resolved fluorescence (TRF), and can be configured with injectors which can inject and read at the point of measurement.

In order to comply with current results and protocols generated by the use of our current PHERAstar equipment, only one brand of microplate reader can be chosen. Use of an alternate device would, at a minimum, increase the cost and cause delay while it was validated to preserve the integrity of the protocols in use, with significant potential for invalidating results within the constant stream of screens passing though the automated robotic facility.

This acquisition is restricted to BMG Labtech, as they are the only vendors of the PHERAstar reader.

The estimated cost of the required item is $678,412.00, and is required to be delivered within 6 to 7 weeks ARO.

7. Any other facts supporting the justification. N/A

8. Project Officer Certification. The undersigned program official(s) certifies that the information in support of this justification for the proposed acquisition has been reviewed, is completed and correct to the best of my knowledge and belief and recommends approval.

Project Officer Date

9. Contracting Officer Certification. The Contracting Officer certifies that the justification for the proposed acquisition has been reviewed and that to the best of my knowledge and belief the information and/or data provided to support the rationale and recommendation for approval is accurate and complete and in accordance with FAR 13.106-1(b)(1), the facts of this acquisition preclude the use of full and open competition.

Contracting Officer Date

“Source Selection Information – see FAR 2.101 and 3.104”