SOW_-_AMBIS_1752944.docx

Statement of Work

ZEPHYR and SCICLONE Service Contract

Proposed Vendor:

PerkinElmer Health Sciences Inc.

710 Bridgeport Avenue Shelton, CT 06484-4794

Phone: 1-800-762-4000 Fax: (203) 944-4914

A-Background Information The Vaccine Research Center at the National Institutes of Health will conduct research that facilitates the development of effective AIDS vaccines. Activities in the Center will include 1) basic research to establish mechanisms of inducing long-lasting protective immunity against HIV and other pathogens that present special challenges to vaccine development, 2) the conception, design, and preparation of vaccine candidates for HIV and related viruses, and 3) laboratory analysis, animal testing, and clinical trials of such candidates. The VRC will conduct a comprehensive program of research on the NIH intramural campus and work with scientists in academic, clinical, and industrial laboratories through a program of national and international collaborations. The VRC will actively seek industrial partners for the development, efficacy testing, and marketing of vaccines and focus the development of new methodologies and training opportunities that will benefit all HIV vaccine researchers. The potential scientific advances, methodologies, and resources will also provide the basis for research on vaccines for other diseases.

The Vaccine Research Center (VRC) is developing vaccines for HIV, Ebola and potentially, other diseases. The human immunology section is involved in a number of projects that require the generation of genomic sequences to determine the T cell receptor usage by HIV-specific CD8 T cells as well as the gene expression analysis of T and B cells after vaccination or in an infection setting. We also are interested in the HIV quasispecies that are present in a variety of tissues. With this knowledge, we are better able to understand the immunologic response that must be generated during a vaccine regimen aiding in the protection of persons against known pathogens.

B-Purpose and Objective of the Service

To maintain the instruments that generate library sequences originating from tissues from phenotypically sorted cells from a variety of tissues.

C-Contract Requirements

The proposed contract will guarantee the following:

· Zephyr workstation repair services (includes parts, labor, travel and phone support).

· Sciclone Workstation repair services (includes parts, labor, travel and phone support).

· 6 month warranty

· Timely delivery, set up and training if applicable.

D. CONTRACTOR SUPPLIED MATERIALS

The contractor will supply all the necessary instruments and reagents produce library molecules able to be detected on the Illumina sequencing platform as listed in the contract requirements.

E. Government Furnished Materials The government furnished materials will include samples that have been prepared as per instructions by the contractor. In brief, samples (tissue or sorted cells) will be prepared to run on the instrument per manufacturer’s instructions.

F. REPORTING REQUIREMENT AND DELIVERABLES

The contractor will inform the Douek Lab members as well as the PI the progress of the delivery and set up of the instrument.

G-Period of Performance and Timeline

This contract is good for a period of 6 months. From 10/17/2015-04/16/2016.