FlowJo - Notice of Intent to sole source.pdf

12/29

PRE-SOLICITATION NON-COMPETITIVE (NOTICE OF INTENT) SYNOPSIS

INTRODUCTION

THIS IS A PRE-SOLICITATION NON-COMPETITIVE (NOTICE OF INTENT)

SYNOPSIS TO AWARD A CONTRACT OR PURCHASE ORDER WITHOUT

PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME).

The National Heart, Lung, and Blood Institute (NHLBI), Office of Acquisitions (OA) on behalf of the National Institute of Arthritus and Musculoskelteal and Skin Diseases (NIAMS) intends to negotiate and award a Purchase Order without providing for full and open competition to FlowJo, Inc. for Flow Cytometry Analysis software.

NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE

The intended procurement is classified under NAICS code 513210 with a Size Standard of $47.0 million.

REGULATORY AUTHORITY

The resultant contract will include all applicable provisions and clauses in effect through the Federal Acquisition Circular (FAC) 2023-01 effective 01 December 2022.

This acquisition is conducted under the procedures as prescribed in FAR Subpart 13.106-1(b).

STATUTORY AUTHORITY

This acquisition is conducted under the authority of 41 U.S.C. 1901 – Simplified Acquisition Procedures.

DESCRIPTION OF REQUIREMENT

Background

The majority of NIAMS investigators use flow cytometry to further their research and consequently require specialized software for post-acquisition data analysis on their desktop workstations and laptop computers. Software packages from the flow cytometer manufacturers are more narrowly focused on their respective platforms and on their own instrument operation. As such, they lack broad applicability beyond immunophenotyping and are not well designed for flow cytometry data file batch analyses or journal-quality graphics.

NIAMS investigators have successfully used FlowJo software for more than ten years and are quite satisfied with its performance and improvements over the time. FlowJo is versatile third-party software written by experienced flow cytometry professionals used to analyze complex data files generated by flow cytometry experiments. Designed originally for the Macintosh operating system more than ten years ago, FlowJo is also available for the PC (Windows) workstations. Currently, it is still the leading third-party software written for native Mac OS X, an operating system used by many NIAMS investigators. Other third-party flow cytometry analysis software options include Win-List (Verity Software House), FCS Express (DeNovo Software) and Kaluza (Beckman Coulter). However, of these options only FCS Express v6+ can now run natively on the Mac OS platform; the others operate on Windows OS only.

The NIAMS Flow Cytometry Section (FCS) within the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) would like to renew the FlowJo License to continue supporting NIAMS research. The software must be operational in both Mac and Windows Operating Systems (OS) platforms.

The majority of NIAMS investigators use flow cytometry to further their research and consequently require specialized software for post-acquisition data analysis on their desktop workstations and laptop computers. Software packages from the flow cytometer manufacturers are more narrowly focused on their respective platforms and on their own instrument operation. As such, they lack broad applicability beyond immunophenotyping and are not well designed for flow cytometry data file batch analyses or journal-quality graphics.

NIAMS investigators have successfully used FlowJo software for more than ten years and are quite satisfied with its performance and improvements over the time. FlowJo is versatile third-party software written by experienced flow cytometry professionals used to analyze complex data files generated by flow cytometry experiments.

Designed originally for the Macintosh operating system more than ten years ago, FlowJo is also available for the PC (Windows) workstations. Currently, it is still the leading third-party software written for native Mac OS X, an operating system used by many NIAMS investigators. Other third-party flow cytometry analysis software options include Win-List (Verity Software House), FCS Express (DeNovo Software) and Kaluza (Beckman Coulter). However, of these options only FCS Express v6+ can now run natively on the Mac OS platform; the others operate on Windows OS only.

The NIAMS Flow Cytometry Section (FCS) within the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) would like to renew the FlowJo License to continue supporting NIAMS research. The software must be operational in both Mac and Windows Operating Systems (OS) platforms.

TYPE OF ORDER

This is a Firm Fixed-Price Purchase Order.

PRODUCT FEATURES/SALIENT CHARACTERISTICS

The software must have the following specifications:

• 180 seats

• Immunophenotyping data analysis, Cell Cycle, Kinetics (Calcium flux), Proliferation (CFSE), Statistical Comparison of samples, Calibration (Quantitation), and Compensation

• tSNE, clustering, multigraph overlay and spectral compensation analysis tools, easy to use options for Batch Analysis and journal-quality graphics export

• Must provide native versions for both Macintosh and Windows platforms

• Easy to add and remove computers to site license with FLS system

• Admin access to usage reports via web interface

• Must be compatible with FCS (Flow Cytometry Standards) 3.1, 3.0 and 2.0

Additional contract requirements:

• Free software upgrades

• Application scientist training seminars once per year (for 25+ users)

• Unlimited Online and Telephone Support 4.1 DELIVERY / INSTALLATION

Delivery/Installation

Software should be delivered within 30 days of purchase order award to:

POC: James Simone Flow Cytometry Section

NIAMS, NIH, DHHS

10 Center Drive Room 10C208 Bethesda, MD 20892-1560 Email: simonej@mail.nih.gov Phone: 301-594-6191 POP: Base Year: 1/18/23 to 1/17/24

Option Year 1: 1/18/24 to 1/17/25 Option Year 2: 1/18/25 to 1/17/26 Option Year 3: 1/18/26 to 1/17/27

TRAINING

Once per year training seminar for 25+ employees

PAYMENT

Payment will be issue after within 30 days after invoice is received.

CLOSING STATEMENT

This is not a request for competitive proposals. However, interested parties may identify their interest and capability to respond to this notice. Responses to this notice shall contain sufficient information to establish the interested parties’ bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Unique Entity Identifier (UEI), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.”

A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement.

All responses must be received by Friday, January 6, 2022 12:00 P.M. EST. Responses must be submitted via email to derek.bowks@nih.gov.

“All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency.”

http://www.sam.gov/ mailto:derek.bowks@nih.gov