D_Purchase Description.pdf

PURCHASE DESCRIPTION

1. Statement of Need and Purpose:

The National Institute on Aging (NIA), Laboratory of Genetics & Genomics (LGG), Functional Epigenomics Unit (FEU) requires an incubator and bioreactor that can grow 3D cultures (spheroids, organoids, cell aggregates and biopsies) that best mimic organ structure in vivo.

2. Background Information and Objective:

The FEU will use the incubator and bioreactor to grow organoids/spheroids of mouse and human tissue over prolonged periods mimicking aging in vitro as well as perform genetic manipulations and drug screens to identify new targets of aging reducing dependence on animal models.

3. Generic Name of Product: Incubator/Bioreactor

4. Purchase Description: Bioreactor and Incubator System with Control Unit

5. Salient characteristics:

All deliverables required under this contract shall be packaged, marked, and shipped in accordance with Government specifications. At a minimum, all deliverables shall be marked with the contract number and Contractor name. The Contractor shall guarantee that all required materials shall be delivered in immediate usable and acceptable condition.

The Vendor must be able to provide these specifications:

• Temperature and humidity-controlled chamber;

• Ability to rotate at adjustable speeds with very low shear forces;

• Allow for the optimal growth of spheroids, and

• Small footprint due to limited lab space.

6. Quantity:

• Bioreactor 12 pack – Six (6)

• Incubator System with Control Unit – Two (2)

7. Delivery Date: Sixty (60) days after receipt of purchase order

8. Period of Performance: N/A

9. Option(s): N/A