D_Purchase Description.pdf

Version 11-30-2016-1 FAR Part 11—Describing Agency Needs

PURCHASE DESCRIPTION

1. Statement of Need and Purpose: This request is for a fixed stage microscope to support the advance of research in neurodegenerative diseases within the Laboratory of Neurogenetics.

2. Background Information and Objective: imaging technology improves to capture The National Institute on Aging (NIA), Laboratory of Neurogenetics works to understand abnormal neuron activity and its contributions to the clinical symptoms of various neurological disorders. For example, the reduction of midbrain dopaminergic neuron activity and associated dopamine release is responsible for the deleterious movement abnormalities in Parkinson’s disease. The requested fixed stage microscope will support our electrophysiology system to allow precise measurement of neuron activity and dopamine release in brain slices derived from Parkinson’s disease-related rodent models. We expect the results will advance our current understanding of the pathogenic mechanism of neurodegenerative diseases and help to design new therapeutics.

3. Generic Name of Product: Fixed Stage Microscope

4. Purchase Description:

Item Description Quantity BX51WIF; Microscope Stand with front fine/coarse focus 1 MT-2200, MPC-385 Bundle for BX51WI 1 Vertical Micropipette Puller F/Short Taper Pipette 1 P-1000 Glass Puller 1

U-ETR-4;TRINOCULAR OBSER TUBE,ERECT,100%PHOTO

IMPRVD IR,ECOG

Eyepiece for BX/IX, 10x Focusing w/ =24mm t=1.5mm Retical Shelf, FN22 Objectives

MPLN5X-1-7;M PLAN 5X OBJECTIVE NA 0.1, WD 20MM 1

LUMPLFLN40XW; LWD PLAN FLUOR 40X WTR DIPPING OBJ 1

WI-NPA; FOCUSING ARM FOR NOSEPIECE ON BX51WIF AND

BX62WIF

WI-SRE3;SWING-OUT NOSEPIECE 1

WI-DICD; LONG WORKING DISTANCE SINGLE DIC CONDENSER 1

Halogen Lamp House, 12V/100W, WEEE/ROHS Compliant 1 JC12V100WHAL-L; 12V,100W Halogen Bulb, 2 Extension Cable for Halogen Lamp House, 2M 1 Power Supply for Halogen Lamp House, 1

TH4-HS-1-5;HAND SWITCH FOR TH4W/INTNSTY CNTRL DIAL, 1

Item Description Quantity UYCP-11; US Style 3-prong Power Cord 1

WI-DICTHRA2; DIC PRISM FOR WI-SRE3/WI-SNPXLU2 1

850nm Hot Mirror 45mm Dia 1

WI-DIC40HR; NOMAR PRISM 40X LUMPL 1

32BP775;775NM/100 BANDPASS FILTER 1

U-AN-2;ANALYZER FOR BX3 REFLECTD ILLUMINATORS 1

32PO;32MM ROUND POLARIZER FOR VISIBLE TO 775NM 1

BX-URA2-5; UNIV REFLECTED ILLUM, BX2 1

pE-4000 Light Source with manual control 1 pE-4000 High speed accessory bundle. 1 Collimating adaptor for pE-100 LLG, 1 pE-6501 USB-TTL Conversion Kit with 5 BNC outputs 1 U-MF2; Empty Mirror Cube, Narrow Style 1 DAPI/FITC/Texas Red LED Multiband filter set 1 01-ELECTRO-M-14-C-OC; Retiga ELECTRO 1.4MP 1

U-TV1XC;C-MOUNT CAMERA ADAPTER, 1

750x900mm CLEANBENCH W/1/4-20 HOLES 1 Full enclosure for 750x900mm Clean Bench 1 FARRADAY CAGE FOR 750X900mm TABLE, 1 ONTRAK PACKING SYSTEM FOR 750x900mm 1 Sub-shelf for 900mm wide Table 1

RETRACTABLE CASTERS, SET OF 4 1

Compressor for Tables, includes regulator and air filter 1

Salient characteristics All deliverables required under this contract shall be packaged, marked and shipped in accordance with Government specifications. At a minimum, all deliverables shall be marked with the contract number and Contractor name. The Contractor shall guarantee that all required materials shall be delivered in immediate usable and acceptable condition.

Interested vendors must be able to provide a fixed stage microscope that can meet the following specifications:

Generic Name of Product: Fixed stage microscope

Manufacturer’s Name: Olympus America Inc.

Brand Name of Product: Olympus BX51WI fixed stage microscope

Salient Characteristics:

Brightfield observation feature Darkfield observation feature Blue/green and ultraviolet excitations observation features Differential interference contrast feature IR-differential interference contrast feature Simple polarized light Fluorescence illuminator 75 W Xenon lamp Motorized focusing mechanism Manual terret intermediate magnification changer Right hand manual stage control Mechanical IX-SVL2 cross stage with short left handle NA 0.9/ W.D. 1.5 mm for 1.25X–100X [swing-out: 1.25X–4X, with oil top lens: (NA 1.4/ W.D. 0.63 mm)] manual universal condenser NA 0.9/ W.D. 2 mm (1.25X–100X) swing-out condenser NA 0.8/ W.D. 5.7 mm (10X–100X) long working distance universal condenser NA 0.8/ W.D. 5.7 mm (10X–100X) long working distance DIC condenser NA 0.8/ W.D. 5.7 mm (10X–100X) long working distance oblique condenser Trinocular for infrared and erected trinocular widefield observation tubes Footprint size no larger than 317.5 mm x 567 mm x 503.8 mm Weigh less than 21 kg

5. Quantity: One (1)

6. Delivery Date: Delivery date of 6 months after receipt of completed purchase order

7. Period of Performance: Manufacturer warranty for one calendar year beginning date of receipt.

8. Option(s): Not applicable