D_Attachment 1 - Purchase Description - Blacktek.pdf

Version 11-30-2016-1 FAR Part 11—Describing Agency Needs

PURCHASE DESCRIPTION

Brand Name or Equal: Luigs & Neumann Micromanipulator

1. Statement of Need and Purpose:

The National Institute of Neurological Disorders and Stroke (NINDS) requires three new brand name or equal Luigs & Neumann micromanipulators to replace previous micromanipulators, which were damaged in a flood at NIH Building 35 in Dec. 2022.

2. Background Information and Objective:

The National Institutes of Health (NIH) is an agency of the Department of Health and Human Services and the Federal focal point for health research. Its mission is to seek fundamental knowledge about the nature and behavior of living systems and apply that knowledge to enhance health, lengthen life, and reduce illness and disability.

The NINDS, which is an Institute within the NIH, seeks to reduce the burden of neurological disease through supporting and conducting basic, translational, and clinical research on the healthy and diseased nervous system, fostering the training of investigators in the basic and clinical neurosciences, and seeking better understanding, diagnosis, treatment, and prevention of neurological disorders. to find out as much as possible about the brain and nervous system in order to lessen the burden of neurological disease.

The synaptic communication between the millions of neurons in our brain is what allows it to function normally. Understanding the chemical basis of synaptic transmission under normal and abnormal circumstances is our aim of NINDS’ Synaptic Transmission Section, which investigates the molecular mechanisms underlying SNARE complex formation and interaction in cultured neurons from the hippocampus and adrenal medulla. This research could help in the diagnosis and treatment of prevalent neurological conditions like Alzheimer's disease.

The fields of synaptic transmission and exocytosis research will both benefit from a quality micromanipulator. An effective micromanipulator is a crucial piece of kit for NINDS’ research as without it, the electrophysiological experiment would be impossible to perform

3. Generic Name of Product:

Micromanipulator

4. Purchase Description:

• Brand name or Equal benchmark: Luigs & Neumann Micromanipulator

• Manufacturer’s name: Luigs & Neumann

Version 11-30-2016-1 FAR Part 11—Describing Agency Needs

5. Salient characteristics The required equipment must meet or exceed the following minimum salient physical, functional, and performance characteristics:

• The ability for the unit to combine the flexibility (XYZ: 25 mm), stability, high resolution (4-8 nm), and a drift-free experience.

• All mechanical components must be equipped with grounding points.

• The unit must be available with a turn adapter, back-fold adapter, or the fast exchange system.

6. Quantity: 3 micromanipulators that include the following brand name or equal items:

7. Delivery Date:

8 weeks after receipt of order

8. Delivery Requirements: The Contractor shall deliver the required equipment in coordination with Government officials. Delivery must be FOB Destination and must include inside installation. The equipment shall be delivered and installed between the hours of 8:00am and 5:00pm, Bethesda, MD local prevailing time, Monday through Friday.

Item Number

Item Description Quantity Destination

1 Set of 4 bolts to adjust column height 83mm, 50mm, 35mm, 15mm

3 Shipped to Building 35

2 Round column Ø 40 mm 3 Shipped to Building 35 3 Unit Mini 25, 3 axes, right side 3 Shipped to Building 35 4 LN electrode bracket stabilization for HEKA EPC 10 3 Shipped to Building 35

5 Compact II - 4 axes 3 Shipped to Building 35

PURCHASE DESCRIPTION