Bruker Specs. 20-178a.pdf

1. PRODUCT CODE: HKURSVA1 - ONE DAY ON-SITE APPLICATION VISIT

Charge for on-site applications or training visit by qualified Bruker personnel to be scheduled within one year of system installation at times mutually agreeable to both the customer and Bruker. Quantity reflects the total days. – QUANTITY (2)

2. PRODUCT CODE: PH2504 - VT dewar with mounting kit MICWB40 VT Dewar with mounting kit – QUANTITY (1) EA

3. PRODUCT CODE: AV4300WB - AVANCE NEO 300 MHz WB NMR SPECTROMETER

HIGH PERFORMANCE DIGITAL NMR SPECTROMETER - QUANTITY (1) EA

Bruker Shim and Sample Transfer System Bruker high performance matrix Orthogonal Shim System (BOSS- WB) with 20 gradients (BOSS-1), low current and low heat dissipation design for optimum homogeneity.

Bruker wide bore Sample Transfer (BST) system for sample insertion into the magnetic centre.

Prepared for shim system cooling.

Basic system characteristics The AVANCE NEO system console electronics is housed within a stainless steel RF 19-inch rack mounted (e.g. One Bay or one bay or double bay) cabinet with full RF shielding (e.g. immunity against DVB-T, ATSC, ISDB-T and DTMB).

The cabinet offers enough space to incorporate various 19-inch high power RF amplifiers depending on application and configuration.

It incorporates a state-of-the-art Ethernet ROUTER providing up to 14 TCP/IP based Ethernet ports for internal and external spectrometer devices such as magnet control and monitoring equipment, solid state NMR accessories, etc.

The system is equipped with a Power Distribution Unit (PDU) to allow software controlled console power-up and power-down via TopSpin™.

A dedicated, on-system Embedded Processing Unit (EPU) with separate 1TB Hard Disk drive allows versatile and flexible spectrometer control.

Acquisition (AQS) characteristics

• 80 MHz system clock, synchronicity on all channels within 12.5ns

• A Timing and Gradient Control Unit (GTU) for all gradient amplifiers. It controls the overall timing of system (all RF channels, gradients, real time pulses, triggers, etc.)

• Up to 8 Transceiver units (TRX1200). Each TRX1200 provides a full broad banded transmit and a full broad banded receive channel up to 1.2 GHz. See other TRX1200 specifications below.

• Gradient control with a resolution of 12.5ns for Z and XYZ gradients (option)

• Pulse program synchronization with up to 4 Trigger inputs at 12.5ns resolution (e.g. for high speed MAS rotor synchronization @111kHz)

• NMR synchronized and real-time control output of external devices (e.g. laser systems, pumps). Up to 11 independent controls with 12.5ns resolution

Bruker Smart Magnet control System (BSMS) supports

• Ultra-stable shim current sources (SCB20) for Bruker RT shim systems

• Optional Ethernet based Bruker Digital NMR Lock (2G DigiLock™) for 2H and/or 19F nuclei (L- TRX, L-19F) together with ultra-stable, ultra-low noise B0 current source (ELCB)

• Bruker Smart Variable Temperature control (BSVT) controls with up to 4 independent VT channels, optional Bruker SmartCoolers™ (e.g. BCU-I), optional Low Temperature accessories (LN2 exchanger / evaporator) and High Temperature equipment

• 10A High Resolution NMR gradient amplifiers (GAB/2, optional)

• NMR Sample Transport for Bruker standard and wide bore magnet sample transport systems (BST)Systems equipped with 2G DigiLock™ and SmartVT™ support intrinsically the unique Bruker NMR Thermometer™ (e.g. to monitor and regulate the sample temperature within the sample tube).

High performance and high power preamplifier system (HPPR)

• Multi-receive ready up to 8 receiver channels. No extra wiring or other component required

• Stray field compliant touch screen based human machine interface (HMI). Easy magic angle setup on the probe

• RF power supervision for fast shut downs built-in (probe safety together with PICS)

• Accurate tuning and matching with factory calibrated preamplifiers (Network analyzer technology) and fully integrated automatic tuning and matching (with ATM probe). No separate unit needed

• Supports up to 8 RF preamplifiers

4. PRODUCT CODE: MAGASC300WB - MAGASC300WB Ascend 300 WB ASCEND™ 300 MHz/89 mm Long Hold Time Magnet superconducting magnet system, 89 mm bore - QUANTITY (1) EA

- operation field at 7.05 Tesla

- Strayfield: radial 0.55m / axial 1.0m - helium hold time >240 days

- helium level meter with alarm function for low helium level

- nitrogen level sensor

- standard magnet stand with elastomer vibration damping accessory

Advanced magnet design, for significant reduction of the stray field and cryogen consumption.

Incorporates External Disturbance Suppression (EDS™) for dramatic reduction of the effects of magnetic field perturbations from sources such as subways and electric trains.

5. PRODUCT CODE: Z53144 - Nitrogen refill set - QUANTITY (1) EA

The corrugated plastic tubing is especially designed for nitrogen refilling. It's available as set 3 meters long and provided with two small (5 cm) pieces of silicon tubing that fit to the nitrogen inlet ports

6. PRODUCT CODE: AH0065 - AH0065 Up to Gimbal - QUANTITY (1) EA

Upgrade of magnet vibration isolation posts to Gimbal type isolators for reduction of the effects of strong floor vibrations in both the vertical and horizontal directions

7 .PRODUCT CODE: AH0070 - AH0070 Helium Transfer Line - QUANTITY (1) EA

Standard Helium Transfer Line

8. PRODUCT CODE: AH0243 - SHIM CURRENT BOARD (SCB20) - QUANTITY (1) EA

The SCB20 high precision, ultra-stable shim current board provides 20 shim current sources with each 20Bit digital resolution and +/- 1A shim current range. Depending on shim system type two units might be necessary. The current sources are compatible with all Bruker Orthogonal and Matrix shim systems (e.g. BOSS-3).

9. PRODUCT CODE: BH0264 - 1H GaAs PREAMPLIFIER (HPLNA 1H) Highly linear, low noise, GaAs based preamplifier for 1H and 19F observe and decoupling with - QUANTITY (1) EA

• Noise Figure (NF) ~1dB including all internal filters and active transmit-receive switch Max. 4kW peak power RF capability

• Build in RF power detection • Factory calibrated for accurate tuning and matching

10. PRODUCT CODE: BH0269 - BB19F GaAs PREAMPLIFIER (HPPR XBB19F 2HP) Linear, low noise, GaAs based broad banded preamplifier for observe and decoupling of nuclei from 57Fe up to 19F - QUANTITY

(1) EA with:

• Noise Figure (NF) ~1.4dB including all internal filters and active transmit-receive switch

• Max. 500W peak power RF capability

• Factory calibrated for accurate tuning and matching

• Built-in 1H stop filter

This broad banded RF preamplifier module is designed to be used with broad banded probes.

11. PRODUCT CODE: SHS000-04 - TopSpin4 acquisition and processing licence - QUANTITY (1) EA

TopSpin 4 acquisition and processing license including:

• NMR data acquisition (arbitrary dimensions) and processing (1D, 2D, 3D, 4D and 5D)

• TopGuide, menu guided acquisition setup

• NMRGuide for training of users in use of 1D and 2D experiments with NMR literature library

• Icon NMR automation interface

Structure Analysis Software:

• Relaxation analysis (T1/T2)

• Integration of 1D and 2D spectra

• Deconvolution of 1D and 2D spectra

• NMRSIM for experiment simulation

• Daisy spectrum simulation software

• TopSpin interactive and automatic multiplet analysis

• TopSpin solid state lineshape analysis

• TopSpin integrated structure editor

• TopSolids integrated solid state NMR set-up

• CMC-assist, supporting NMR Data Interpretation

• Processing of Non Uniformly Sampled (NUS) data for 2D spectra

12. PRODUCT CODE: AH1015 - VARIABLE TEMPERATURE CONTROL (BSVT) - QUANTITY (1) EA

The Bruker SmartVT (BSVT) is a highly integrated unit to provide

• Digital temperature sensor resolution better than 5Mk

• Temperature stability depends on environment and probe (e.g. 10mK/K for HR RT probes)

• Supports various temperature sensor types (e.g. thermocouple T or E, PT100)

• VT gas flow monitoring up to 3000lph with mass flow regulation

• Anti-freeze mode for CryoProbes built-in (probe safety)

• Up to 4 independent heater channels (e.g. flow probes)

• High temperature measurements ready (up to 600°C with high temperature probes), no separate heater (booster) needed

• Intelligent VT gas flow control for easy sample insertion with different kind of spinners (ceramic, KEL-F, etc.). No manual adjustments needed (e.g. SampleCase, SampleJet)

• Intelligent SmartCoolersTM (BCU) and low temperature accessories control (LN2 exchanger/evaporator)

• Accurate Sample Temperature determination and regulation with NMR ThermometerTM

13. PRODUCT CODE: BH2075 - RF CHANNEL (TRX1200) - QUANTITY (2) EA

The TRX1200 is a highly integrated NMR RF transceiver (transmit and receive) unit with built-in pulse program engine (sequencer, waveform memory) providing

• RF signal bandwidth of 5 to 1200 MHz for transmit and receive

• Timing resolution of 12.5 ns

• Simultaneous RF amplitude, phase & frequency setting within 12.5ns

• High speed ADC, 240 MSPS @16 Bit, Digital Down Converter (DDC)

• High speed DAC, 960 MSPS, Digital Up Converter (DUC)

• High intermediate frequency (IF) for transmit and receive of 1852 MHz (e.g. no unwanted LO windows)

• Sequencer waveform memory 1GB (e.g. pulse shaping, optimal control applications, composite pulse decoupling)

Spectral width up to 7.5 MHz

• Effective dynamic range >17 Bit (5 MHz) / >19 Bit (1 MHz) / >23 Bit (6 kHz)

14. PRODUCT CODE: BH3410 - 1CH HIGH BAND RF AMPLIFIER (BLAH500) - QUANTITY (1) EA

Linear single channel RF amplifier for observe and decoupling with either

• Min. 500W RF peak power @180 – 600 MHz (max. 50W CW)

• Min. 100W RF peak power @180 – 600 MHz (max. 20W CW) or

• Min. 500W RF peak power @650 – 900 MHz (max. 50W CW)

• Min. 100W RF peak power @650 – 900 MHz (max. 20W CW) or

• Min. 500W RF peak power @890 – 1000 MHz (max. 50W CW)

• Min. 100W RF peak power @890 – 1000 MHz (max. 20W CW)

• High / Low power RF mode switchable by software

Pulse program controlled blanking, ultra-fast rise/fall times. Built-in computer controlled RF amplifier safety with forward / reflected RF power monitoring. Ethernet interface for service and NMR system integration.

15. PRODUCT CODE: BH3420 - 1CH BROAD BAND RF AMPLIFIER (BLABB500) - QUANTITY (1) EA

Linear single channel RF amplifier for observe and decoupling with

• Min. 500W RF peak power @15 – 600 MHz (max. 50W CW)

Pulse program controlled blanking, ultra-fast rise/fall times and very low droop. It provides two identical RF outputs connecting to different preamplifiers when appropriate (no manual re-wiring). Built-in computer controlled RF amplifier safety with forward / reflected RF power monitoring. Ethernet interface for service and NMR system integration.

16. PRODUCT CODE: BH2381 - Gradient Amplifier 60A - QUANTITY (1) EA

The GREAT 1/60 is a fast single channel gradient amplifier unit for high power diffusion and microimaging applications. It provides gradient currents up to 60A, has a built-in pre-emphasis capability for eddy current compensation and integrated amplifier blanking. High power diffusion operation requires a single GREAT1/60. In case the NMR console does not provide enough space to incorporate GREAT1/60 a separate MIC-DIFF CABINET (AH2385) is required. Micro-Imaging operation requires additional two GREAT1/60 units (optional, BH2382) and separate MIC-DIFF CABINET (AH2385).

17. PRODUCT CODE: BH2384 - AV4 SAFETY CONTROLLER - QUANTITY (1) EA

The SAFETY CONTROLLER monitors gradient amplifier operation and gradient coil temperatures for high power diffusion and micro-imaging applications. It shuts down the gradient amplifier system whenever a critical condition arises.

18. PRODUCT CODE: BH2382 - Upgrade Gradient Amplifier 1/60 to 3 - QUANTITY (1) EA

Additional two GREAT1/60 units to extend single Z-gradient High power diffusion (DIFF) to XYZgradient Micro-Imaging (MIC) functionality. Provides. Each GREAT 1/60 provides gradient currents up to 60A, has a built-in pre-emphasis capability for eddy current compensation and integrated amplifier blanking.

Requires BH2381 (GREAT1/60) for Z-gradient.

19. PRODUCT CODE: AH2385 - MIC-DIFF CABINET - QUANTITY (1) EA

The high power diffusion and/or micro-imaging electronics for SB and WB systems is housed within a separate stainless steel RF 19-inch rack mounted one bay style cabinet with full RF shielding (e.g.

immunity against DVB-T, ATSC, ISDB-T and DTMB). The MIC-DIFF cabinet offers enough space to incorporate various 19-inch high power gradient amplifiers and a safety controller. Depending on application, it may also incorporate other equipment in future. It incorporates a state-of-the-art

Ethernet Switch with up to 8 TCP/IP based Ethernet ports for internal spectrometer devices. The system is equipped with a Power Distribution Unit (PDU) to allow software controlled console power-up and power-down via TopSpin™. Together with the AVANCE NEO electronics the system offers intrinsically B0 shift compensation via the standard GTU and TRX1200. The daisy chain gradient amplifier topology of AVANCE NEO allows controlling up to 3 GREAT1/60, up to 3 GAB/2 and a SAFETY Controller.

20. PRODUCT CODE: AH2386 - GRADIENT CHILLER (BCU-20) - QUANTITY (1) EA

The BCU-20 provides thermally stabilized coolant water to the gradient of the probe. Required for High Power Diffusion and Micro-Imaging applications

21. PRODUCT CODE: T119634 - MICWB40 RES 300 1H 040/005 LTR - QUANTITY (1) EA

22. PRODUCT CODE: T119633 - MICWB40 RES 300 1H 040/010 LTR - QUANTITY (1) EA

23. PRODUCT CODE: T119632 - MICWB40 RES 300 1H 040/015 LTR - QUANTITY (1) EA

24. PRODUCT CODE: T119630 - MICWB40 RES 300 1H 040/020 QTR - QUANTITY (1) EA

25. PRODUCT CODE: T119629 - MICWB40 RES 300 1H 040/025 QTR - QUANTITY (1) EA

26. PRODUCT CODE: PH2502 - MICWB40 PROBE BODY SET - QUANTITY (1) EA

27. PRODUCT CODE: T119628 - MICWB40 RES 300 1H 040/030 QTR - QUANTITY (1) EA

28. PRODUCT CODE: PH2519 - Quad Combiner Quad Combiner - QUANTITY (1) EA

29. PRODUCT CODE: PCIMAG - PCIMAG NMR LINUX Workstation for MicroImaging - QUANTITY (1) EA

Microimaging PC with 64 GB RAM for processing of large data sets On computers with less RAM, very large 2D and 3D data sets cannot be acquired and processed for all methods of PV6

30. PRODUCT CODE: AP2521 - 24 inch TFT MONITOR - QUANTITY (1) EA

31. PRODUCT CODE: STP7100 - PV7 Package for MicroImaging - QUANTITY (1) EA

ParaVision 360 Package for MicroImaging for the acquisition of images and of localized spectroscopy.

The package contains the following subpackages:

ParaVision 360 Core (GUI, processing, visualization, and data handling), 3D interactive viewing, Maximum intensity projection (MIP), Multi-planar secondary image reconstruction (MPR), Surface rendering, Movie generation (3D Visualization) MRI Comprehensive (Basic morphology in MRI), STPV700

Methods: FLASH, SegFLASH, MSME, FISP, RARE, MDEFT, SINGLE PULSE, NSPECT, SWI, Dixon, CEST (Basic morphology); IG-FLASH (Cardio); MGE, RAREvtr (Relaxometry)

MR Imaging Plus (Functional imaging applications in MRI), STPV701

Methods: DTI-SE, DTI-EPI, T1-EPI, T2-EPI, T2*-EPI, DTI-Spiral (Diffusion); EPI, CASL-EPI, FAIR-EPI, FAIR- RARE Spiral (fMRI, DCE, Perfusion); IG-UTE, Flowmap (Adv. Cardio, Angio); UTE, UTE3D, ZTE, RAREst (Short TE) MR Spectroscopy (Metabolic applications in MRI), STPV702

Methods: CSI, EPSI*, PRESS, STEAM, ISIS (Spectroscopy)

Method Development (Modify and develop own methods), STPV703 PVM source code of most template methods - for AVANCE NEO spectrometers

32. Support and Installation - QUANTITY (1) EA

Complete set of system documentation provided in BASH CDROM format.

Complete system installation, including magnet, by qualified personnel. Cryogens and rigging equipment needed for the assembly of the magnet are not included and must be provided by the customer, unless otherwise noted elsewhere in the quotation. Standard samples will be provided by Bruker BioSpin on a temporary basis for meeting specifications.

33. PRODUCT CODE: HKURSV1 ONE DAY TRAINING COURSE TUITION Charge for tuition to Bruker BioSpin training courses held at Bruker facilities. Tuitions must be used within one year of system delivery. Quantity reflects the combined total days of all training courses. Course registration is required in advance and enrollment may be limited. See www.bruker.com for a list and schedule of training courses. Does not include any customer travel, lodging and meals costs; those costs are the sole responsibility of the customer. - QUANTITY (10) EA