Attachment-PURCHASE DESCRIPTION DNA Analyzer.pdf

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Attached to
DNA Analyzer Federal contract opportunity
Solicitation number
75N95021Q00199
Issued by
Department of Health and Human Services National Institutes of Health National Institute on Drug Abuse

About this file

This document contains a combined synopsis and solicitation for a DNA analyzer. The National Institute on Aging, Laboratory of Neurogenetics requires a DNA analyzer to support Alzheimer's disease research. The solicitation seeks a fixed price purchase order for one DNA analyzer from Life Technologies Corporation/ThermoFisher, including the analyzer unit, software, consumables, and support. Responses are due by August 18, 2021 to the National Institute on Drug Abuse on behalf of the National Institute on Aging. The solicitation will result in a non-competitive award due to the specialized needs of the research laboratory. Technical capability and past performance are more important than price in evaluation.

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Attachment-Invoicing Instructions 20210210 GuidanceInvoiceSubmissionEmail.pdf PDF
Attachment-FAR_52.204-24 (Oct 2020).pdf PDF
Attachment-FAR 52.212-4 Addendum.pdf PDF
Attachment-FAR 52.212-5 (Jul 2021).pdf PDF
Attachment-FAR_52.204-26 (Oct 2020).pdf PDF

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Text version

Version 11-30-2016-1 FAR Part 11—Describing Agency Needs

PURCHASE DESCRIPTION

1. Statement of Need and Purpose: This acquisition is necessary for DNA sequencing and analysis of DNA samples to support the research of novel amino acid mutation discoveries in the scope of Alzheimer’s Disease Research within the Laboratory of Neurogenetics.

2. Background Information and Objective:

The National Institute on Aging, Laboratory of Neurogenetics works to understand the pathological basis of neurodegenerative diseases mainly Alzheimer’s Disease. The purpose of this acquisition is to provide a DNA analyzer for analysis of DNA changes associated with Alzheimer’s Disease and other neurodegenerative disease disorders. A DNA analyzer is a powerful, standard genetic analysis device that provides microsatellite-based fragment analysis, de novo sequencing, resequencing, and single-nucleotide polymorphism (SNP) genotyping analysis.

3. Generic Name of Product: DNA analyzer

4. Purchase Description:

3730XL-48/96 GEN ALYZR SKU# A41046

Software Bundle* SKU# 4443764

3730 BDT V3.1 SEQ/FRAG INSTALL KIT SKU# 4337193

96WELL SEPTA PLATE KIT 3730 EACH SKU# 4336131

3730XL 96X36CM CAP ARRAY INSTL KIT SKU# 4339251

HI-DI FORMAMIDE BOTTLE 25 ML SKU# 4311320

3730 BUFFER(10X) W/EDTA 500ML EACH SKU# 4335613

POP7-3730/3730XL DNA ANALYZERS SIN SKU# 4363929

SW, GENEMAPPER V6B 5 CLIENT LIC COMBO KIT SKU# A45741

*A software bundle consisting of Windows 10 and Windows 7 compatible versions of all CE secondary analysis software (Sequencing Analysis Software 7, SeqScape 4, Variant Reporter 3, GeneMapper 6)

5. Salient characteristics All deliverables required under this contract shall be packaged, marked and shipped in accordance with Government specifications. At a minimum, all deliverables shall be marked with the contract number and Contractor name. The Contractor shall guarantee that all required materials shall be delivered in immediate usable and acceptable condition.

Instrument must provide these notable features:

Instrument shall be designed to allow the use of both 48 or 96 capillary arrays in either of two lengths, 36-cm and 50-cm, without the need for any hardware modifications.

The instrument capillary array shall be constructed using internally uncoated capillaries and warranted for 300 sample runs.

The instrument shall be able to process successive runs without requiring a capillary array washing or conditioning step.

The instrument shall be able to process 768- 6912 sequencing analysis samples in 24 hours.

The instrument shall be able to process at least 3,000 fragment analysis samples in 24 hours.

The instrument shall be capable of housing 16 sample plates, either 96-well, 384-well or a combination of, simultaneously.

The instrument shall be designed to allow users to add or remove sample plates from the instrument without interrupting the run progress.

The instrument shall be able to detect and analyze six fluorescent dyes simultaneously.

The instrument shall be designed to allow semi-automated on-board cleaning of the automated separation matrix (polymer) capillary filling mechanism without the need to remove or disassemble any capillary filling mechanism components other than to flush the water fill trap monthly.

The instrument shall have an internal barcode reader that scans and recognizes the following types of barcodes on sample plates: code 128, code 39, code 93, LOGMARS, and EAN-8.

The instrument shall be designed to provide an onboard piercing mechanism (enclosed inside the system) for piercing of sealing film covering the sample plates.

The instrument shall be designed to provide a thermally stable detection region of the capillary array.

The instrument shall employ a fixed single solid-state laser which operates in single longitudinal mode and illuminates all capillaries in the array simultaneously. The instrument’s solid-state laser shall have a 10,000-hour warranty life span.

6. Quantity:

3730XL-48/96 GEN ALYZR SKU# A41046

QTY: 1

Software Bundle SKU# 4443764

QTY: 1

3730 BDT V3.1 SEQ/FRAG INSTALL KIT SKU# 4337193

QTY: 1

96WELL SEPTA PLATE KIT 3730 EACH SKU# 4336131

3730XL 96X36CM CAP ARRAY INSTL KIT SKU# 4339251

HI-DI FORMAMIDE BOTTLE 25 ML SKU# 4311320

QTY: 1

3730 BUFFER(10X) W/EDTA 500ML EACH SKU# 4335613

QTY: 1

POP7-3730/3730XL DNA ANALYZERS SIN SKU# 4363929

QTY: 1

SW, GENEMAPPER V6B 5 CLIENT LIC COMBO KIT SKU# A45741

7. Delivery Date: 6 months after receipt of purchase order

8. Period of Performance: Not applicable

9. Option(s): Not applicable

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