Attachment 1 - Purchase Description.pdf
PDF 140 KB Posted
- Attached to
- Flash Purification Chromatography System with Automated Mass Directed Fraction Collection Federal contract opportunity
- Solicitation number
- 75N95022Q00452
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Other files for this federal contract opportunity
| File | Type | Posted |
|---|---|---|
| Attachment 3 - FAR 52.212-5 (May 2022)_22-005659 print.pdf | ||
| Attachment 4 - FAR 52.204-24, 52.204-26, and 52.212-3 Reps and Certs.pdf | ||
| 75N95022Q00452_Competitive Synopsis Solicitation.pdf | ||
| Attachment 6 - Invoice Instructions (IPP and non-IPP).pdf | ||
| Attachment 2 - FAR 52.212-4 (Nov 2021).pdf | ||
| Attachment 5 - Buy American Certificate.pdf |
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Version 11-30-2016-1 FAR Part 11—Describing Agency Needs
PURCHASE DESCRIPTION
1. Statement of Need and Purpose: This purchase is intended to minimize manual steps in the chemist’s workflow of fraction collection and mass verification for compound identification during purification by chromatography.
2. Background Information and Objective: NCATS chemists confirm the mass of compounds eluting in fractions collected during flash silica gel purification by manually taking aliquots from several fractions, entering these aliquots to separately located reverse phase LCMS systems, and then waiting for LCMS results to determine what fractions contain compounds of their interest. The Biotage Isolera Dalton will be a dedicated normal flash purification system that will not only collect fractions based on UV but also acquire the mass spectrum of compounds while they are being eluted into fractions. This will significantly cut down the manual step of acquiring the LCMS separately of fractions in order to verify the identity of the compounds.
3. Generic Name of Product: Biotage Isolera + Dalton 2000 System or Equal
4. Purchase Description: Flash Purification Chromatography System with Automated
Mass Directed Fraction Collection
5. Salient characteristics
Dimensions (W x D x H) Isolera™ Dalton Mass Detector: 35.5 x 56 x 25 cm
Isolera™ Dalton Nanolink: 35.4 x 52.5 x 21 cm
Isolera™ Dalton System: 85 x 59 x 62 cm
Weight Isolera™ Dalton Mass Detector: 32 kg
Isolera™ Dalton Nanolink: 10 kg
Isolera™: 35 kg
Isolera™ Dalton System: 77 kg
Miniaturized, single quadrupole mass analyzer
Chip-based electrospray ionization
Detection range m/z 80–800
Mass accuracy ± m/z 0.5 in full scan in a temperature controlled environment,±3 °C
Mass resolution m/z 0.7 ±0.1 FWHM in full scan in a temperature controlled environment, ±3 °C
Automatic sampling adjustment
Start-up time of 30 minutes
Fully integrated vacuum pumps
Isolera™ Spektra Control interface
User serviceable parts Spraychip® (chip based ESI source)
Version 11-30-2016-1 FAR Part 11—Describing Agency Needs
Vac-chip™ (microengineered atmospheric pressure interface)
Compatible with Isolera™ Spektra flash chromatography systems
Gas requirement 2–6 bar N2
Gas consumption 2.5 L/min
Power requirement 100–240 V AC; 50–60 Hz
Power consumption 320 VA (Isolera™ Dalton Detector)
Power consumption 130 VA (Isolera™ Dalton Nanolink)
Certifications: CE, cTÜVus
Inclusion of first year maintenance (minimum of one year)
6. Quantity: One (1) system
7. Delivery Date: To be delivered within ninety (90) days after receipt of order
8. Period of Performance: N/A
9. Option(s): N/A
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