Attachment 1 -Prodcut Description.pdf
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- Attached to
- Molecular Devices FLIPR Penta High-Throughput Cellular Screening System Federal contract opportunity
- Solicitation number
- NCATS-20-004407
About this file
This document is a combined synopsis and solicitation for a Molecular Devices FLIPR Penta high-throughput cellular screening system. The National Center for the Advancement of Translational Sciences (NCATS) requires one FLIPR Penta instrument with attachments and supporting reagents to enable high-speed membrane potential assays and detection in 96-, 384-, and 1536-well formats using an EMCCD camera and user-configurable pipettors. Delivery is required within 6-7 weeks to the specified address at the National Institutes of Health campus in Rockville, Maryland. Vendors should reference solicitation number NCATS-20-004407 when responding to this request for quote by the unspecified due date.
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Other files for this federal contract opportunity
| File | Type | Posted |
|---|---|---|
| Attachment 3 -52.212-5 Contract Terms and Conditions Required to Implement Statutes or Executive Orders -Commercial Items.pdf | ||
| Attachment 4 -NIH Invoice Instructions.pdf | ||
| Attachment 2 -52.204-24 Rep & Cert.pdf | ||
| Attachment 5-Interim Electronic Invoicing Instructions_Apr 2020.pdf | ||
| COMBINED SYNOPSIS and SOLICITATION_NCATS-20-004407.pdf |
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Text version
PURCHASE DESCRIPTION
1. Statement of Need and Purpose:
Acquisition of one Molecular Devices FLIPR Penta high-throughput cellular screening system.
2. Background Information and Objective:
The Stem Cell Translational Laboratory (SCTL) seeks to purchase one Molecular Devices FLIPR Penta high-throughput cellular screening system and associated robotics and reagents to address key technological needs for characterization of GPCR, ion channels and neuronal activity in stem-cell derived neural cell types, all of which have strong implications on the pain and opioid addiction fields of research. SCTL’s robotic screening system currently features instrumentation to support automated screening of luminescence, fluorescence and cell-based assays (reagent dispenser, incubators, pintool, and robotic arms), but lacks the capability to perform the extremely time-sensitive dispense/measure flux assays (100Hz data acquisition, calcium/potassium flux, membrane potential) that are standard in the GPCR, ion channel and stem cell fields.
The addition of these FLIPR Penta instruments will make it possible for SCTL to perform state-of-the-art assays in these timely and extremely important scientific domains in a fully automated fashion.
3. Generic Name of Product High-throughput cellular screening system
4. Type of Purchase Description Brand-name or Equal
5. Physical, Functional, and Performance Specifications
The Molecular Devices FLIPR Penta system is commercially available items that are customized with options to fit the specific laboratory needs. The unit will be outfitted as follows:
Part Number Line Item Description FLIPR PENTA FLIPR Penta System Includes: Win 10 Computer Tip
Washer Heated Stage 1 year warranty covering parts & labor Requires: Standard or Aequorin or High-Speed Camera Pipettor Head Installation & Training
5073652 High-Speed Camera, EMCCD, PENTA No Cell Suspen No cell suspension kit, FLIPR
0200-6071 FLIPR PENTA HEAD KIT, 96-WELL
0200-6073 FLIPR PENTA HEAD KIT, 1536-WELL
0200-6072 FLIPR PENTA HEAD KIT, 384-WELL
0310-5148 FLIPR Penta Aequorin, ICCD camera.
0200-6207 FLIPR Penta, Penta Membrane Potential Optics Kit 1536 HEAD ASSY FLIPR PENTA+ 1536 pin tool head kit. Pin holder and pins need to be purchased separately.
384 HEAD ASSY FLIPR PENTA+ 384 pin tool head kit. Pin holder and pins need to be purchased separately.
1536 HOLDER ASSY FLIPR PENTA+ 1536 pin tool holder. Pin tool head and pins need to be purchased separately.
384 HOLDER ASSY FLIPR PENTA+ 384 pin tool holder. Pin tool head and pins need to be purchased separately.
5074364 FLIPR Cycler (previously TetraCycler) Factory installation.
0200-6207 FLIPR Penta Membrane Potential Optics kit 1310-FP1NS10 1540 Pins, slotted, .457 Dia, 10nl 1310-FP1NS50 1540 Pins, slotted, .457 Dia, 50nl 1310-FP1NS100 388 Pins, slotted, .787 Dia, 100nl DD-CUSTOM IonFields TipCharger 1536 Customization for the FLIPR includes installation 5074843 ScreenWorks Peak Pro 2 Software Module.
Purchase delivers product key and instructions for activation of the software features within ScreenWorks Software.
FLIPR-TRAINING-OS FLIPR instrument training, onsite, one day, max 4 people
FLIPR-INSTALL-OS FLIPR instrument installation, onsite
The brand name or equal multimodal high-throughput cellular screening systems must meet requirements and have the capabilities detailed below:
• High-speed EMCCD camera capable of both standard fluorescence and aequorin luminescence detection to enable membrane potential assays/detection
• User-configurable 96-, 384-, and 1536-well pipettors/pin tools
• User-exchangeable cell suspension option
• Intuitive, user-friendly ScreenWorks Peak Pro 2 software interface
• Internal plate handler for accelerated throughput
• Field installation and training (one-day on-site)
6. Quantity
One (1) FLIPR PENTA instrument (with attachments and supporting reagents)
7. Delivery Date or Period of Performance 6-7 weeks ARO
8. Delivery Location Address: National Center for the Advancement of Translational Sciences, 9800 Medical Center Dr.
Bldg B Rockville, MD 20850
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