Appendix B.pdf
PDF 125 KB Posted
- Attached to
- Administrative Support for Chernobyl Projects in Ukraine Federal contract opportunity
- Solicitation number
- 75N91020C00008_mod6
About this file
This notice provides details for a contract modification to support Chernobyl-related research projects in Ukraine. The Department of Health and Human Services, National Institutes of Health, National Cancer Institute intends to modify an existing contract with the Science and Technology Center in Ukraine to add tasks including conducting a dosimetry feasibility study, creating an inventory of specimens from the Chernobyl Tissue Bank, and evaluating tracing individuals from dosimetry groups for interviews. The contractor will continue providing administrative support for two collaborations between NCI and Ukrainian research institutions, the Clinical Cohort of Ukrainian Cleanup Workers project and the Ukrainian Thyroid Cohort/Breast Cancer Project. The contract value including options is $1,663,255. Capability statements from interested parties will be accepted until December 2nd, though no new contract is anticipated as the work is considered only achievable by the incumbent, Science and Technology Center in Ukraine.
View the file
Other files for this federal contract opportunity
| File | Type | Posted |
|---|---|---|
| Appendix A.pdf |
On GovTribe
Work with this file on GovTribe
- Download the original file
- Contacts named in this file
- Similar government files
- Ask GovTribe AI about this file
Text version
APPENDIX B. TASKS FOR THE INSTITUTE OF ENDOCRINOLOGY AND
METABOLISM (IEM) [Ukrainian Thyroid Cohort/Breast Cancer Project]
Option Task 22B: CTB Inventory (Six months)
• Create a complete inventory with patient and specimen information for specimens collected between February 1, 2021 and June 30, 2022, including fresh frozen thyroid tumors tissues, normal thyroid tissues and metastatic tissues (if any); formalin-fixed paraffin-embedded (FFPE) tissues; whole blood as well as demographic (e.g., date of birth, sex, place of residence at the time of the accident) and clinical-pathological (e.g., clinical diagnosis, tumor stage, treatment given, tumor size, histological characteristics, whenever available).
• Deliver inventory data spreadsheet as requested by NCI. No personally identifiable information shall be sent to NCI.
Option Task 23B: CTB dosimetry feasibility study (Six Months)
• Evaluate feasibility to trace, locate and contact at least 120 individuals from the CTB dosimetry groups ##2, 3 and 4 who are the subjects of the study of radiation-related genomic profile of papillary thyroid cancer after the Chernobyl accident with available FFPE thyroid tissue samples.
• Evaluate feasibility to conduct personal dosimetry interviews with traced individuals from the CTB dosimetry groups ##2, 3 and 4 using the dosimetry questionnaire.
Project staff shall use telephone/mail for interviewing. Each subject enrolled in the study shall be nominally compensated for his / her time spent for the interview.
• Incorporate the collected questionnaire dosimetry data into the dose reconstruction model to calculate individual thyroid doses from 131I intake and associated uncertainties.
• Calculate individual thyroid doses from 131I intake for individuals from the CTB dosimetry groups ##2, 3 and 4 with whom the personal dosimetry interview has been conducted.
• Deliver report summarizing results of feasibility study and calculation of thyroid doses to the NCI. Deliver dataset with sample information as requested by NCI. No personally identifiable information shall be sent.
File details come from the government source that posted it. Updated .