Attachment_1-Purchase_Description.pdf

Solicitation Number 75N95019Q00108 Attachment 1

Version 11-30-2016-1 FAR Part 11—Describing Agency Needs

PURCHASE DESCRIPTION

Statement of Need and Purpose: The purpose of this acquisition is to obtain brand-name only BioTek AMX associated modules and accessories to develop and perform cellular assays for the Stem Cell Translation Laboratory (SCTL) within the National Center for Advancing Translational Sciences (NCATS) Division of Preclinical Innovation (DPI). The BioTek AMX module enables gentle automated media exchange to protect and encourage proliferation of spheroids, tumoroids and other 3D cell structures, 2D and suspension cells in microplate-based assays. The BioTek BioStack 4 is a compact and versatile microplate stacker compatible with BioTek’s washers, dispensers, detectors and imaging systems. Its rapid plate exchange speeds increase throughput and enhance productivity, accommodating assay workflows for 96- and 384-well plates. It also offers efficient de-lidding and re-lidding of microplates for sensitive cell-based assays.

Background Information and Objective: The opioid crisis highlights the urgent need for novel non-addictive pain medications, as well as improved treatments for opioid addiction and overdose. There is a need for pharmacological agents directed at novel targets to test new therapeutic hypotheses, new clinic-ready drugs directed at those targets, and new testing systems with the potential to be more predictive of human clinical response than traditionally used models. Through the Helping to End Addiction Long-term (HEAL) Initiative, NCATS will focus on the development of human cell-based models of opioid misuse and addiction and of pain. The Stem Cell Translation Laboratory (SCTL) is a state-of-the-art research facility within NCATS’ Division of Pre-Clinical Innovation dedicated to addressing the scientific and technological challenges in the iPSC field. Specifically, the SCTL aims to develop a renewable supply of human cell-based models focusing on new patient-derived iPSC lines that give rise to specialized, functional nerve cells that are relevant for opioid misuse and addiction, and pain.

Purchase Description: The following brand-name only items at the stated quantities:

1. Name: MultiFlo FX Brand: BioTek Part No.: MFXP2 Quantity: Six (6)

2. Name: Cassette: 10 - 3,000 μL, 10 μL Increments, Plastic Tips

Part No.: 7170010 Quantity: Twelve (12)

3. Name: Secondary Peristaltic Pump Dispenser Module

Part No.: 7210010

4. Name: 1x16-tube Manifold

Part No.: 7180543S

5. Name: PERIWASH MODULE COMPLETE

Part No.: 1260041 Quantity: Five (5)

6. Name: Dual Syringe Dispenser Module - Autoclavable

Part No.: 7210008

7. Name: ACCESS WASHER MODULE 96W

Part No.: 1260023

8. Name: SVC BASIC INSTL & TRAINING TIER 2 (for MultiFlo FX)

Part No.: SVCICT1

9. Name: FIELD WARRANTY UPGRADE (for MultiFlo FX)

Part No.: SVCONFWU Quantity: Six (6)

10. Name: EXTENDED 2ND YR WARRANTY (for MultiFlo FX) Brand: BioTek Part No.: SVC2YRWAR Quantity: Six (6)

11. Name: BioStack4 Brand: BioTek Part No.: BIOSTACK4

12. Name: ACCESSORIES ALIGN MULTIFLO 3WR

Part No.: 7310044

13. Name: ACCESS STACK 30 PLATE LID

Part No.: 1230004

14. Name: SVC BASIC INSTL & TRAINING TIER 1 (for BioStack4)

Part No.: SVCICT

15. Name: FIELD WARRANTY UPGRADE (for BioStack4)

Part No.: SVCONFWU Quantity: Six (6)

16. Name: EXTENDED 2ND YR WARRANTY (for BioStack4) Brand: BioTek Part No.: SVC2YRWAR Quantity: Six (6)

Shipping, installation, and setup are to be included. The contractor shall ensure that all items are packaged, packed, and marked in accordance with best commercial practices to ensure safe and timely delivery at the intended destination.

Salient Characteristics:

The equipment must be compatible in all aspects (form, fit, and function) with existing systems presently installed. The current equipment is the BioTek EL-406 liquid handler, and the new item must coordinate, connect, and interface with the existing system.

Delivery Date: Within thirty (30) days after receipt of order (ARO).

Delivery Location: All items shall be shipped FOB destination to the following address:

ATTN: Pinar Ormanoglu / Pepper Bonney

NIH/NCATS

9800 Medical Center Drive Rockville, Maryland 20850