36C26223P0717_2.docx

Justification and Approval Notice Justification and Approval Notice

GENERAL INFORMATION

BASE NOTICE TYPE

Network Contracting Office 22 4811 Airport Plaza Drive Suite 600 Long Beach CA 90815

POINT OF CONTACT*

Rochelle Malveaux Rochelle Malveaux rochelle.malveaux@va.gov 562-766-2353

AWARD INFORMATION

MODIFICATION NUMBER

LINE ITEM NUMBER

AWARDEE NAME*

CONTRACTOR’S UEI

JACKSON LABORATORY

XR6LMXNKDJJ1

AWARDEE ADDRESS LINE 1*

AWARDEE ADDRESS LINE 2*

AWARDEE ADDRESS LINE 4*

ADDITIONAL INFORMATION

DESCRIPTION

VHAPG Part 813.106 Simplified Acquisition Procedures: Soliciting from a Single Source Attachment 1: Single Source Justification for SAP under the SAT

DEPARTMENT OF VETERANS AFFAIRS

Justification for Single Source Awards IAW FAR 13.106-1 For Over Micro-Purchase Threshold but Not Exceeding the SAT ($250K)

Acquisition Plan Action ID:_36C262-23-AP-2322___________

1. Contracting Activity: Department of Veterans Affairs, Regional Procurement Office West (RPOW), Network Contracting Office 22 (NCO-22), 4811 Airport Plaza Drive, Suite 600, Long Beach, CA 90815.

Transaction Number: 600-23-2-2352-0062

2. Brief Description of Supplies/ Services required and the intended use/Estimated Amount:

This is an urgent request for immunologically humanized mice for a four-year VA funded research program. The clinical trials will be conducted by the research study team under Dr Ling Gao; who has been mandated to perform a Preclinical investigation of P13k inhibition and immune checkpoint blockade combination therapy for treatment of Merkel cell carcinoma. Deliveries for the engrafted mice supply will be scheduled whenever needed as ordered by the Research team and taken from the same cohort for effective observational outcomes.

Estimated amount: $42,540.17

3. Unique characteristics that limit availability to only one source, with the reason no other supplies or services can be used:

The research study comprised of the supply of Humanized Mice models; is necessary for “Preclinical Investigation of P13K Inhibition and Immune Checkpoint Blackade Combination Therapy for Treatment of Merkel Cell Carcinoma Using Humanized Mouse Models”. As a year long study, the department requires engrafted mice which are readily available and come from the same co-hort for the duration of the study. The Jackson Laboratory, a large business; maintains an inventory of CD34+ hematopoietic stem cell mice with various strains, as well as the genotypes of strains with identified molecular mutations, which can fulfill this requirement. The humanized mice in the vendor’s live inventory meet the specific engraftment criteria required for the Doctor led study. The Jackson Laboratory submitted a proprietary memo regarding the specialized development of the immunologically humanized mice models and has been developing the models specifically for this VA led research. Additionally, the VA has partnered with this supplier to provide a previous order as part of this study.

VHAPG Part 813.106 Simplified Acquisition Procedures: Soliciting from a Single Source Attachment 1: Single Source Justification for SAP under the SAT

4. Description of market research conducted and results or statement why it was not conducted:

A search of the SAC did not return any mandatory contracts for this item. Search results on GSA Federal Supply Schedule did not return any listing for the items. A search of the Prime Vendor list and the GSA Federal Supply schedule did not return any listing for this specific supply item. Additional market research did not list information for this supply item on the NAC database. The Jackson Laboratory is not an SDVOSB/VOSB vendor. However, further research revealed that The Jackson Laboratory is registered on SAM.gov and is not listed on the excluded parties list.

5. Contracting Officer's Certification: Purchase is approved in accordance with FAR13.106-1(b). I certify that the foregoing justification is accurate and complete to the best of my knowledge and belief.

Prepared By: Approved By:

Contract Specialist Contracting Officer Network Contracting Office (NCO) 22 Network Contracting Office (NCO) 22

Justification and Approval Notice