36C25020Q0032.docx

Contract Opportunity Combined Synopsis/Solicitation Notice

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MULTIPHOTON MICROSCOPE

44131 36C25020Q0032 12-02-2019 N 333314 Department of Veterans Affairs Network Contracting Office (NCO) 10 6150 Oak Tree Blvd., Suite 300 Independence OH 44131 Rachelle J. Hamer Louis Stokes Cleveland VAMC 10701 East Blvd.

Cleveland, OH 44133

USA

www.va.gov Department of Veterans Affairs rachelle.hamer@va.gov Contracting Officer Combined Synopsis Solicitation: Multiphoton Microscope

1. General:

This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in FAR subpart 12.6 as supplemented with additional information included in this notice. This notice constitutes the only solicitation; quotations are being requested and a written solicitation will not be issued. The solicitation number is 36C25020Q0032 and is issued as a Request for Quote (RFQ). This solicitation document incorporates provisions and clauses are those in effect through Federal Acquisition Circular (FAC) 2020-01, effective November 12, 2019. The applicable North American Industry Classification System Code (NAICS) is 333314 and the small business size standard is 500 employees.

2. Line items:

1 EA Microscope that includes all the Technical Characteristics indicated in paragraph 3 of the technical characteristics.

3. Technical Characteristics:

The Laboratory is interested in purchasing a Multi-photon Microscope system (for 2- and 3-Photon imaging) for real-time imaging of fluorescent samples, built on a confocal microscope platform. The Microscope must be able to image live animals (for 2- and 3-Photon imaging), during both awake and anesthetized measurements of electro-physiological activity and while performing motor tasks. The leading application is brain tissue response to injury or device implantation.

· Microscope stand – System shall include

· Fully automated upright microscope

· Motorized stage optimized for imaging of live animals, fixed tissue, or live cells

· Air table, providing flexibility for experimental space requirements, with laser safety housing to create safe working environment

· Objectives –

· At minimum, 5x and 25x objective, both immersion and dry.

· Working distance for dry objectives shall reach >6 mm with transmission out to at least 1000 nm

· Working distances for 25x water emersion objectives shall reach at least 2.5 mm with transmission out to 1300 nm

· Additional 25x objectives for use with oil, water, or glycerol shall reach at least 6 mm WD, and be compatible with CLARITY techniques with transmission out to 1300 nm

· At least two objectives for single photon imaging and at least 2 objectives for multiphoton imaging (allowable to use the same objective for single and multiphoton imaging)

· Lasers –

· Visible lasers: 488 nm, 552 nm, 638 nm

· System should be user-friendly for novice users, as close to turn-key and/or self-aligning the better

· IR lasers: configured for use with the InSight X3 Dual from Spectra Physics (680 – 1300 nm tunable line and 1045 nm fixed line) for 2- and 3-Photon imaging, or comparable laser

· Scan Head –

· Scan optics with transmission out to at least 1300 nm

· Scanning compatible with quantitative assessment of tissue fluorescence

· Scanner with maximal frame resolution of 8192 x 8192

· Capable of detecting at least 4 channels simultaneously (shall enable imaging beyond 4 colors)

· Motor testing while imaging –

· Neurotar Mobile Cage included in purchase price.

· System would allow for one to perform precise optical and electrophysiological techniques such as multi-photon imaging and electrophysiology measurements in the brain of non-anesthetized, head-fixed and naturally behaving mice. The motion tracker shall collect and display in real time actionable data about the mouse’s movement trajectory and speed and controls the external devices in closed-loop experiments. Motion tracking shall allow for integrating behavioral readouts with high-precision tests that require head-fixation.

· Upgradability – The system shall be capable of both 2 and 3 photon imaging, expandable to longer wavelength detection as technology matures.

· Built on a Confocal Microscope platform – The microscope system shall be built on a confocal microscope platform, to allow for confocal microscopy of explanted tissue using Clarity objectives.

· Support Structure – In addition to the local account manager and confocal/ Multi-Photon sales specialist, there shall be a confocal/ Multi-Photon application specialist available for scheduled onsite and remote assistance and training as needed, offering continued support throughout the life of the microscope. There shall also be a team available to answer immediate questions and for remote troubleshooting through a support line, Monday through Friday, 8 AM – 8 PM Eastern Time.

4. GOVERNMENT HOLIDAYS: National holidays observed by the Federal Government are as follows:

If a holiday falls on Sunday, the following Monday will be observed as the National Holiday. When a holiday falls on a Saturday, the preceding Friday is observed as a National Holiday by the U.S. Government agencies. Also included would be any day specifically declared by the President of the United States of America as a National Holiday.

5. Applicable Provisions and Clauses:

The following clauses apply to this acquisition: FAR Addendum to 52.212-4 Contract Terms and Conditions-Commercial Items; 852.203-70; 852.211-70; 852.232-72; 852.246-71; http://www.acquistion.gov/far/index.html, and http://www.va.gov/oal/library/vaar/index.asp/ ; 52.203-17; 52.204-4; 52.204-13; 52.232-40 (end of addendum 52.212-4) 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders (of which 52.222-3, 52.222-19, 52.222-21, 52.222-26, 52.222-35, 52.222-36, 52.222-37, 52.223-18, 52.225-1, 52.225-13, and 52.232-33 are applicable).

The following provisions apply to this acquisition: Addendum to 52.212-1, Instructions to Offerors-Commercial; 52.232-38; 852.233-70; 852.233-71; http://www.acquistion.gov/far/index.html, and http://www.va.gov/oal/library/vaar/index.asp/ ; 52.204-7 (end of addendum 52.212-1) 52.212-3.

6. Offer Evaluation and Award:

This is a competitive Request for Quotations (RFQ) that will be evaluated and awarded following the procedures in FAR Part 12 and 13 using price and other factors. The Government will issue/award a Firm-Fixed Price Purchase Order or delivery order or contract (as appropriate) to the responsible vendor/contractor/offeror whose quote/offer best conforms to the requirements within the solicitation, and is considered to provide the best value to the Government. The Government reserves the right to select a response that provides benefit to the Government that exceeds the minimum, but is not required to do so. In addition to a price comparison, the other following factors will be evaluated:

Technical;

Delivery; and Past Performance (CPARS)

A Price Comparison will be completed.

An Offeror’s initial quote shall contain the best terms from a price and technical standpoint. Offerors are reminded that representatives from your company SHALL NOT contact any Cleveland VAMC personnel to discuss this RFQ during the solicitation and evaluation process.

In addition to providing a quote, please provide literature to be able determine the product meeting the requested specifications must be provided.

7. Procedure for submitting documents to the Department of Veterans Affairs:

DOCUMENTS THAT ARE TO BE PROVIDED TO THE CONTRACTING OFFICER WILL BE SUBMITTED USING THE APPROPRIATE VEHICLE BELOW.

email: rachelle.hamer@va.gov

8. Submission of Offer.

All information shall be submitted in the manner described below and offerors who do not submit all information may not be considered for award.

a. The vendor/contractor/offeror shall be an Original Equipment Manufacturer (OEM). If not the OEM, then an authorized OEM distributor, dealer, reseller letter for the proposed equipment/system, such that the provided OEM warranty and service are maintained and remain enforceable, must be provided with your response. All warranty and service associated with the equipment/system shall be in accordance with the OEM terms and conditions. The Contractor shall provide new items ONLY; no remanufactured or "gray market" items. All items must be covered by the manufacturer's warranty.

b. F.O.B. shall be destination.

c. This solicitation requires registration with the System for Award Management (SAM) prior to award, pursuant to applicable regulations and guidelines. Registration information can be found at www.sam.gov.

d. Quotes are to be broken out to include line item pricing for each item, and installation including any premium time required.

e. RESPONSES ARE DUE: Monday, December 2, 2019 at 11:00 AM EST. Offers will only be accepted electronically via e-mail to rachelle.hamer@va.gov. Enter “RFQ 36C25020Q0032|Multiphoton Microscope” in the email subject line.