1-Purchase Description.pdf

Version 11-30-2016-1 FAR Part 11—Describing Agency Needs

PURCHASE DESCRIPTION

1. Statement of Need and Purpose: This is for the purchase of a Digital Laser Processing (DLP) printer Brand Name or Equal to the CELLINK BIONOVA X. This DLP is a new capability at NCATS which will be used to 3D print hydrogels in designed shapes directly in a multi-well plate format (up to 96-well plate) to create 3D tissue models.

2. Background Information and Objective: There is a need to establish in vitro predictive assays for drug discovery and development. The NCATS 3D Tissue Bioprinting Laboratory is assembling a portfolio of 3D tissue models in microplate format that can be used for drug testing. To enable the biofabrication of 3D tissues in a multi-well plate format, the CellInk BIONOVA X DLP can create high resolution (10 um), custom-designed 3D structures directly inside wells of a multi-well plate by using Digital Laser Processing technology with biocompatible hydrogels for cell growth. The 3D hydrogel structures can be created on wells that are clear bottom and compatible with high content imaging instruments to enable high through screening. This would be a new capability at NCATS.

3. Generic Name of Product: Digital Laser Processing (DLP) printer

4. Purchase Description:

Brand name or equal products to the following:

• CELLINK BIONOVA X 3D Bioprinter, Item D16110025280

• BIONOVA X Software Package

• BIOINK Discovery Kit, Item d16110025375

• Extended Warranty, Item D16110025286

• On-site installation and training, Item d16110025283

5. Salient characteristics: The requirement is for the brand name or equal products as described in Section 4- Purchase Description that meet the following salient characteristics:

• Direct in-well printing in wells of a multi-well plate of up to 96-well plates

• Digital light projection-based technology

• Auto Alignment

• Ultra-High Resolution with the ability to print down to 10 μm resolution

• Glove friendly touch screen

• Built-in UVC sterilization

• Benchtop with the ability to fit inside a biosafety cabinet.

• Enables grayscale printing for the development of multi-stiffness constructs in all directions and uses specially coated glass bottom well plates that allow the

Version 11-30-2016-1 FAR Part 11—Describing Agency Needs printed hydrogel structure to stick to the bottom of the well and facilitates a streamline workflow for further downstream experiments and analysis, such as high-resolution microscopy, with minimum contact with the print.

• Temperature Control

4. Quantity:

1 of each:

• DLP Printer

• Software package

• Discovery Kit

• Extended warranty

• On-site installation and training

5. Delivery Date: 60 days after receipt of order

6. Address for shipment, installation, and training is:

9800 Medical Center Drive Rockville, MD 20850

USA