This federal Project Grant award of $428,387, provided by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program, supports research to investigate the toxicological consequences of environmentally relevant nanoplastics. The grantee, Purdue University, has developed a novel procedure to reproducibly generate micro- and nanoplastics from common plastic waste materials, allowing for the study of fundamental mechanisms of nanoplastic...
The National Institutes of Health National Institute of Environmental Health Sciences awarded a $924,612 Project Grant to the California State University, East Bay Foundation, Inc. under the Environmental Health (CFDA 93.113) federal grant program. The grant will fund research from August 2022 to July 2025 to advance chemical risk assessment and predictive toxicology through the development, validation and integration of high-throughput mechanistic in vitro assays. Specifically, the grantee will...
This Project Grant award of $749,901, funded by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program, aims to elucidate the origins of the mutational landscape in cancer. The research project will integrate cellular DNA adductomics, nanopore sequencing, and single-molecule duplex sequencing to investigate how exposure to environmental mutagens, such as 1,2,3-trichloropropane, bromochloroacetic acid, and furan, contributes to the...
This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) Federal Grant Program provides $379,504 to the University System of New Hampshire's Keene State College to conduct research on the tissue-specific development of toxicity in response to transgenerational chronic arsenic exposures. The key objectives are to: (1) detect tissue-specific uptake of arsenic in response to transgenerational chronic exposure; (2)...
The National Institute of Environmental Health Sciences (NIEHS) awarded a $231,320 Project Grant under the Environmental Health (CFDA 93.113) federal grant program to Wayne State University (WSU) and Case Western Reserve University (CWRU). The goal of this 5-year program, titled "The Program Integrating Genomics and the Environment (PIGE)", is to train the next generation of researchers to bridge the disciplines of exposure science and genetic epidemiology/genomics. Key features of the...
This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) federal grant program, provides $356,178.00 to Swarthmore College to conduct research on the behavioral effects of ToxCast Phase I chemicals on planarians, with the goal of determining their potential context of use. The research aims to investigate how various environmental exposures, such as chemicals and toxins, can impact biological systems and public...
This federal Project Grant award, provided by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program, supports research to define the neurotoxic and neurodevelopmental health risks of per- and polyfluoroalkyl substances (PFAS). The $546,350 award, effective January 13, 2025 through October 31, 2029, aims to characterize the mechanisms by which PFAS affect brain development and function. Key objectives include defining PFAS uptake...
This $553,708 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) program, aims to advance the development of a community-led Zebrafish Toxicology Phenotype Atlas. The key products and services to be delivered include: Designing and deploying a standardized Toxicophenotype Data Model to improve data compatibility across zebrafish toxicology studies and domains. Creating a Toxicophenotype Annotation Toolkit to...
This federal Project Grant award of $756,318.00 from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health program (CFDA 93.113), will support research investigating the environmental health impacts of polyethoxylated surfactants. The research aims to comprehensively assess how these ubiquitous chemicals disrupt metabolic health, particularly their potential to promote unhealthy visceral adipose expansion through thyroid hormone receptor antagonism....
The National Institute of Environmental Health Sciences (NIEHS) awarded a $292,368 Project Grant under the Environmental Health (CFDA 93.113) federal grant program to the Regents of the University of Michigan. The grant, effective September 1, 2024 through March 31, 2026, will support research to "disentangle the drivers and dangers of toxic cyanobacteria biosynthetic heterogeneity in cyanobacterial harmful algal blooms (CyanoHABs)." The goal is to identify the effects of...