Project Grant SB1AG097192
- This $325,672 Project Grant was awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Advanced Brain Monitoring, Inc., a veteran-owned small business in Carlsbad, California. The grant funds the development and validation of a novel mobile electroencephalography (EEG) platform to provide accessible, cost-effective cognitive assessments for individuals suffering from neurological manifestations of...
- This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $467,538 to Oscilloscape, Inc. (dba Oscillo Biosciences) to develop and test an innovative, wearable digital health device called "SYNG" to help aging adults with Alzheimer's disease and mild cognitive impairment. The device aims to deliver a digital therapy using music and synchronized visual brain stimulation to restore healthy brain rhythms through neural entrainment. Key outcomes...
- This Project Grant award of $475,014.00 from the National Institute on Aging (CFDA 93.866 - Aging Research) aims to develop a novel neurotrophic therapeutic for treating the cognitive deficits associated with Alzheimer's disease. The key products and services to be delivered through this grant include: Scaling up the production of a recombinant, non-erythropoietic neurotrophic protein that has demonstrated cognitive enhancement effects in Alzheimer's disease models. Evaluating the toxicity...
- The Department of Health and Human Services' National Institutes of Health's National Institute on Aging awarded $865,905 under the Aging Research program (CFDA 93.866) to Careband, Inc. to develop the Appraise to Assist system. This project grant will support Careband and its partner Eperture LLC to engineer a system integrating Careband's wearable device and Eperture's tablet platform. The system aims to passively and unobtrusively monitor, empirically measure, and facilitate engagement...
- This $500,000 Project Grant was awarded on September 15, 2024 by the National Institute on Aging (CFDA 93.866 Aging Research program) to Neucyte Inc., a minority-owned small business specializing in advanced biomedical research and development. The funding will support the development of a miniaturized "mini-brain" microphysiological system (MPS) platform using Alzheimer's disease (AD) patient-derived cells. The goal is to create a scalable, reproducible in vitro brain model that can...
- This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) to Aster Labs, Inc. provides $499,758 to develop an automated system for detecting and reporting lapses in the performance of activities of daily living (ADLs) for individuals with Alzheimer's disease and related dementias. The ActivVerify system will leverage a discreet electronic shoe insole with sensors to automatically and accurately detect and identify ADLs, and then determine and verify...
- This Project Grant award of $1,006,653 from the National Institute on Aging (CFDA 93.866 - Aging Research) to Posit Science Corp. supports the "IMPROVING NEUROLOGICAL HEALTH WITH ACETYLCHOLINE VIA NEUROPLASTICITY-BASED COMPUTERIZED EXERCISE IN MILD COGNITIVE IMPAIRMENT (INHANCE-MCI)" program. The project aims to deploy a computerized cognitive training program that integrates validated exercises to potentially reduce the long-term risk of dementia onset in individuals with mild...
- This $2,356,117 federal Project Grant award from the National Institute on Aging's Aging Research program (CFDA 93.866) will support research to improve the perioperative management of patients with Alzheimer's disease and related dementias. The primary objectives are to: (1) identify the extent to which surgical patients with these conditions are at increased risk for adverse postoperative outcomes, and (2) estimate the association between various perioperative interventions and the incidence...
- This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $699,964 to Turing Medical Technologies Inc. (doing business as Nous Imaging, Inc.) to develop "Universal FIRMM", a real-time motion tracking and monitoring solution for all MRI imaging sequences. The objective is to create a software system compatible with any MRI scanner that can detect and reduce patient motion during MRI scans, with a specific focus on improving MRI...
- This federal Project Grant award of $423,500 from the National Institute on Aging (CFDA 93.866 - Aging Research) will support research into the behavioral, electrophysiological, and pupil-based rhythms of attention and memory in young and older adults. The project will examine attention and memory performance concurrently with electroencephalography (EEG) and pupillometry, with a sample of 75 young and 75 cognitively unimpaired older adults screened for Alzheimer's disease pathology. The goal is...
This Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research program) provides $1,998,535 to Pascall Systems, Inc. to commercialize their neuroscience-based EEG-guided precision anesthesia management system. The key products and services being delivered include: Pilot study to determine sample size, cost, and timeline for a Phase III multi-site clinical trial to optimize workflows, outcome measures, and caregiver protocol adherence for the Pascall M1 device. Enhancements to the Pascall M1 device's workflow and manufacturing capabilities, including developing FDA-compliant, in-house manufacturing under ISO 13485:2016 standards. The overall goal is to commercialize the Pascall M1 device, which consists of a wireless anesthetic brain monitor (M0) and personalized algorithms to monitor anesthetic brain state in aging, dementia, and Alzheimer's disease patients. This innovation aims to prevent post-operative delirium in the elderly population.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.0m | 9/18/25 |