This $239,530 Project Grant award from the National Institutes of Health (NIH) Research Infrastructure Programs (CFDA 93.351) will fund the acquisition of a Beckman Coulter CytoFlex Nano flow cytometer at the University of California, Davis. The CytoFlex Nano is designed specifically to support research on extracellular vesicles (EVs), which are small nanometer-sized membrane-bound structures released by cells that are of growing interest for cancer diagnosis and treatment. The new instrument...
The federal Project Grant award, funded by the National Institutes of Health (NIH) under the Research Infrastructure Programs (CFDA 93.351), provides $357,193 to the University of California, San Diego (UCSD) to acquire a NanoString CosMx Single Molecule Imager (SMI) for the Institute of Genomic Medicine (IGM) Genomics Center. The SMI will support spatial-omics research capabilities across UCSD's diverse biomedical research community, encompassing projects related to retinal disease,...
This Project Grant award from the National Institutes of Health (NIH) Research Infrastructure Programs (CFDA 93.351) provides $454,942 to the University of California, San Diego (UCSD) to purchase a Cytek Aurora flow cytometer for the Human Embryonic Stem Cell Core Facility (HESCCF). The new 5-laser, 63-parameter flow cytometer with a 96-well plate high-throughput sample acquisition system will serve the shared research needs of UCSD and the four other Sanford Consortium for Regenerative...
This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $498,000.00 to the University of California, San Diego (UC San Diego) to conduct research on "Multiplex Imaging in Therapy Refractory Tumors: Understanding the Spatiotemporal Facets of an Immunosuppressive Environment". The research, which will be performed from August 1, 2024 to June 30, 2025, aims to...
The University of California, San Diego (UCSD) has been awarded a $100,000 Project Grant from the National Institutes of Health (NIH) Trans-NIH Research Support program (CFDA 93.310) to purchase a new 600 MHz NMR spectrometer with a 1.7 mm micro-cryoprobe and 60-sample changer. This instrument will replace a 15-year-old defunct 600 MHz spectrometer that supported UCSD's research programs in marine natural products discovery, structural biology, drug design, metabolomics, and systems biology. The...
This $333,128 Project Grant award from the National Institutes of Health (NIH) Office of the Director under the Research Infrastructure Programs (CFDA 93.351) provides funding to Children's Hospital Los Angeles (CHLA) to acquire a NanoImager (ONI, Inc.) instrument for the Extracellular Vesicle (EV) Core Facility at the Saban Research Institute. The NanoImager utilizes advanced microscopy techniques to analyze the structural integrity and molecular composition of EVs and lipid nanoparticles,...
This federal Project Grant award from the National Institutes of Health (NIH) under the Research Infrastructure Programs (CFDA 93.351) provides $942,983 to acquire a Bruker Luxendo TruLive3D light-sheet microscope system. The award, effective September 1, 2024 through August 31, 2025, will enable rapid 3D volumetric imaging of live specimens such as mouse, fly, and zebrafish embryos with high resolution and minimal phototoxicity. This advanced microscope system will benefit a user group of...
This federal Project Grant award of $634,038 from the National Institutes of Health (CFDA 93.351 - Research Infrastructure Programs) will provide the University of California, Davis with a BD FACSymphony S6 flow cytometric sorter. This instrument will be integrated into the university's established Flow Cytometry Core facility to support over 20 current NIH-funded research projects spanning basic, translational, and clinical research areas, including studies on therapeutic HIV vaccines, SIV...
The University of California, San Diego (UCSD) was awarded a $587,425 Project Grant from the National Science Foundation (NSF) Engineering program (CFDA 47.041) to develop the first dual-modality super-resolution microscopy system, termed Dual-Modality Localized Plasmonic Structured Illumination Microscopy (DM-LPSIM). This new imaging technology will enable simultaneous high-speed super-resolution fluorescence and label-free scattering imaging at the 50-nanometer scale. The DM-LPSIM system...
The National Science Foundation awarded a $504,179 Project Grant to the University of California, San Diego under the Mathematical and Physical Sciences program (CFDA 47.049) to acquire an XEUSS 3.0 small-angle x-ray scattering instrument with Genix 3D capabilities. The three-year award, which began on October 1, 2021 and runs through September 30, 2024, will fund the purchase of this specialized equipment to advance scientific research capabilities at the awardee institution. As the parent...