Project Grant R61CA297964
- This $163,817 Project Grant was awarded by the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research) to the University of Alabama on July 16, 2025. The project will develop methods to identify Cancer Care Shortage Areas (CCSAs) using geospatial analysis and spatial network optimization techniques. This work aims to inform policies that can improve cancer outcomes and reduce health disparities. The project will run from July 2025 through June 2027. The University of...
- The University of Alabama was awarded a $525,799 Project Grant from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) to conduct research on "Targeting GPNMB to Improve Efficacy of CDK4/6 Inhibitors in ER+ Breast Cancer". The 3-year research project, beginning September 1, 2025, aims to develop innovative medical solutions that address critical health challenges relevant to military personnel and the broader public. The University of...
- The University of Chicago received a $372,628 Project Grant from the National Cancer Institute (CFDA 93.394 - Cancer Detection and Diagnosis Research) on September 12, 2025. The grant funds the development of a large-format spatial transcriptomics profiling platform, called Array-Seq, to enable detailed spatiomolecular analysis of human cancer samples. This technology aims to overcome limitations of existing spatial transcriptomics methods by increasing throughput, sample size compatibility, and...
- The National Cancer Institute (NCI) awarded a $591,468 Project Grant on August 6, 2025 under the Cancer Detection and Diagnosis Research program (CFDA 93.394) to The Research Foundation for the State University of New York (SUNY Oswego). The funding supports research to develop explainable machine learning models based on deep cancer pathophysiology to improve cancer diagnosis, risk stratification, and therapeutic recommendations. The project aims to address key gaps in integrating heterogeneous...
- The federal Project Grant award of $457,185.00, awarded by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420), supports a research project led by Clemson University to characterize fallopian tube-derived extracellular vesicles for the discovery of ovarian cancer biomarkers. The 2-year project, running from July 1, 2024 to June 30, 2026, will leverage Clemson University's expertise in areas like cancer research, biomedical engineering, and...
- The Defense Health Agency awarded a $321,404 Project Grant to the University of Birmingham under the Military Medical Research and Development program (CFDA 12.420) to support "The Application of AI-Defined Molecular Classifications in Ovarian Cancer". The award, which commenced on September 1, 2024 and runs through August 31, 2026, will enable the University of Birmingham to conduct innovative biomedical research aimed at improving health outcomes for military service members,...
- This Project Grant award from the National Cancer Institute (CFDA 93.395 - Cancer Treatment Research) provides $465,020 to the University of Maryland, Baltimore (UMB) to conduct research on the mechanisms by which chemotherapy can inadvertently promote metastasis in epithelial ovarian cancer. The research aims to determine how clinically approved chemotherapies activate tumor-associated membrane-anchored serine proteases (MASPs) in a way that potentiates tumor dissemination and metastatic...
- This Project Grant award from the National Cancer Institute (CFDA 93.394 - Cancer Detection and Diagnosis Research) provides $386,700.00 to the Regents of the University of Minnesota to develop and validate targeted mass spectrometry assays for the early diagnosis of serous ovarian cancer. The project aims to differentiate ovarian cancer patients from healthy individuals by analyzing protein biomarkers in a cohort of 1,300 serum samples. The successful completion of these preclinical studies...
- The University of Michigan has been awarded a $568,151 Project Grant from the National Cancer Institute (CFDA 93.394 - Cancer Detection and Diagnosis Research) to develop a real-time functional imaging platform for accurate diagnosis and prognosis of prostate cancer. The project aims to leverage photoacoustic imaging and biocompatible hydrogel nanoparticle probes to quantitatively assess prostate gland microarchitecture and tumor microenvironment as imaging biomarkers for improved prostate...
- The National Cancer Institute (NCI), part of the Department of Health and Human Services, awarded a $1,274,742 Project Grant under the Cancer Detection and Diagnosis Research program (CFDA 93.394) to Northwestern University. The project aims to engineer a high-performing microfluidic system for the rapid, non-invasive isolation and expansion of circulating tumor-reactive lymphocytes (CTRLs) from blood samples. This innovation could accelerate the development of effective anti-tumor cellular...
The University of Alabama was awarded a $631,621 Project Grant from the National Cancer Institute (CFDA 93.394 - Cancer Detection and Diagnosis Research) on August 13, 2025 to develop an integrated top-down proteomics and phosphoproteomics platform to generate personalized intact proteome maps from patient-derived ovarian cancer spheroids. This research aims to characterize ovarian cancer disease states and identify markers of chemoresistance, which is critical as ovarian cancer is currently the deadliest gynecological malignancy. The project will run through July 31, 2028. The proposed work leverages the University's expertise in areas like materials science, biomedical engineering, and computational analysis to advance cancer detection and diagnosis capabilities.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $631.6k | 8/12/25 |