The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $1,373,036 Project Grant under the Alcohol Research Programs (CFDA 93.273) to Yale University. The overarching goal of this 5-year research project (Sep 2024 - Aug 2029) is to enhance the understanding and prediction of heavy drinking episodes during initial recovery from alcohol use disorder (AUD). The project aims to leverage wearable biosensor technology and artificial intelligence to develop real-time predictive...
This federal Project Grant award of $1,135,243 from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) will support research to investigate changes in neural mechanisms associated with cognitive reappraisal and alcohol cue reactivity during early abstinence from alcohol use disorder (AUD) treatment. The research, conducted by the University of Colorado-Denver and involving sub-awards to Emory University and the University of Denver,...
This federal Project Grant award of $683,611 from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) supports research to optimize the engagement and clinical outcomes of a "smart" digital therapeutic for alcohol use disorder (AUD). The project aims to embed a machine learning-based lapse prediction model into an existing digital therapeutic called A-CHESS and evaluate how different components of daily engagement messages...
This federal Project Grant award of $710,992, provided by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), supports a longitudinal study to understand the trajectory, mechanisms, and impacts of changes in emotion processing deficits during early alcohol use disorder (AUD) recovery. The University of Florida, the primary awardee, will recruit recently abstinent individuals in residential AUD treatment and a matched community control...
This $711,808 Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) will support a multi-year research project at Yale University to investigate the neural mechanisms underlying the stress response and its relationship to chronic alcohol consumption. The key objectives of the research are to: 1) develop a connectome-based model to predict stress responses using functional MRI data, 2) characterize dynamic...
This Project Grant award of $1,613,395 from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) will fund a study to examine whether adolescent music engagement is a protective factor against substance use behaviors. The primary goal is to analyze existing longitudinal, genetic, and environmental datasets, including the Adolescent Brain Cognitive Development (ABCD) Study and the Colorado Adoption/Twin Study of Lifespan Behavioral...
This Project Grant award of $1,320,881 from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273), will fund a randomized controlled trial to evaluate the efficacy of a smartphone-based intervention to reduce drinking among adults experiencing homelessness. The proposed project, titled "Efficacy of a Smartphone-Based Just-In-Time Adaptive Intervention to Reduce Drinking Among Adults Experiencing Homelessness," will build...
This federal Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273) grant program, provides funding of $573,607.01 for a project titled "Digital Phenotyping of Anxiety and Anxiety-Related Alcohol Comorbidity and Treatment." The project aims to develop a personalized cognitive-behavioral therapy (CBT) skills-based intervention for individuals with co-occurring anxiety disorders and alcohol use...
The federal Project Grant award R00AA030665 was provided by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273) federal grant program. The $249,001 award, effective May 1, 2025, supports a study entitled "Study Aimed at Increasing Alcohol Abstinence (DEDICATE)" to be conducted by the University of Illinois. The key objectives of this project are to (1) test the efficacy of combining contingency management (CM) with...
This federal Project Grant award of $581,869 from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the CFDA 93.273 Alcohol Research Programs, will fund a human neuroscience study to investigate the role of glucocorticoid receptor (GR) antagonism in alcohol use disorder (AUD). The study will evaluate the effects of a selective GR antagonist, PT150, on behavioral, neuroendocrinological, and physiological responses to stress and alcohol in 34 participants. The research aims...