Project Grant R44CA291331

Award Date 9/9/24
Completion Date 8/31/26
Dollars Obligated $1.4M
Federal Grant Program
93.395
Assistance Type
Project Grant
Place of Performance
California, USA
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This Project Grant award from the National Cancer Institute (CFDA 93.395 - Cancer Treatment Research) provides $400,000 to Kure Ai Inc. to develop a novel CAR-T cell therapy product targeting the MR1 antigen expressed on the surface of various tumor cells, including acute myeloid leukemia (AML) and glioblastoma. The key objectives are to: 1) assess MR1 expression in primary patient AML and glioblastoma samples, 2) perform mouse efficacy studies using AML and glioblastoma models, and 3)...
This federal Project Grant award from the National Cancer Institute (CFDA 93.395 Cancer Treatment Research) provides $768,437.00 to the Sanford Burnham Prebys Medical Discovery Institute (SBP) to conduct research aimed at identifying chemical compounds that inhibit the chromatin reader SGF29, which has been identified as a regulator of oncogene transcription in acute myeloid leukemia (AML). The goal of the project is to implement high-throughput screening assays developed by SBP to discover...
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