Project Grant R43HL157291
- The National Science Foundation (NSF) awarded a $305,000 STTR Phase I project grant to Sensvita Inc. under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program. The project aims to develop a non-invasive radio frequency sensing technology for home-based monitoring of heart and lung function. The proposed system uses advanced sensing methods to measure critical physiological parameters without the need for skin contact or maintenance, improving the convenience, scalability,...
- The National Heart, Lung, and Blood Institute (NHLBI) awarded a $349,734 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to Actiox LLC, a biomedical technology company in Thousand Oaks, California. The project aims to develop a wearable microneedle-based biosensor for continuous, real-time cardiac troponin I monitoring. The goal is to demonstrate the feasibility of this transformative biosensor technology to enable earlier detection of ischemic events and...
- This $500,000 Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports the development of the Hemotago HATS-OFF (Hemotag Assessment for Short-Term Outcomes of Heart Failure) technology by Aventusoft LLC, a small disadvantaged business in Boca Raton, Florida. The HATS-OFF system provides a non-invasive, at-home method for long-term monitoring of heart failure patients to detect decompensation early and enable timely therapy...
- This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), provides $295,895 to Ricovr Healthcare Inc. to develop a rapid, low-cost, point-of-care (POC) diagnostic platform for quantitative measurement of placental growth factor (PlGF) to predict and detect pre-eclampsia. The goal is to create an objective, affordable POC tool to improve the clinical diagnosis and monitoring of pre-eclampsia, which...
- This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) aims to advance geriatric palliative care by assessing the feasibility and acceptability of using radio frequency (RF) sensors to capture cardiopulmonary measures in nursing home patients with Alzheimer's disease and related dementias (ADRD). The $451,721 award to Weill Medical College of Cornell University will also develop a machine learning algorithm to autonomously detect and predict respiratory...
- This Project Grant award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $398,630.00 to the University of Alabama's Office for Sponsored Programs Division to develop an advanced, battery-free wireless sensor system for continuous monitoring of patients with chronic conditions like heart failure. The project aims to translate research on parity-time (PT) symmetric biotelemetry, inspired by non-Hermitian quantum physics, into...
- This Project Grant award from the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) provides $585,794 to Tele-Stethoscope Inc., a self-certified small disadvantaged business, to develop a novel mobile phone technology that can detect preeclampsia and hypertension. The key products to be delivered under this award include: Proof-of-concept demonstration that ordinary mobile phones can accurately reproduce a physician's diagnosis of preeclampsia....
- The National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research federal grant program (CFDA 93.837), awarded a $306,872 project grant to Vena Vitals Inc., a women-owned small business in Irvine, California. The grant funding supports the development of "VeriSleep", a wearable device that can provide continuous, non-invasive monitoring of cardiovascular biomarkers during sleep. The goal is to create a robust, cost-effective solution that can capture...
- This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), will evaluate the use of mobile devices to extract vital signs to monitor patients with asthma. The $459,127 award to M5 Enterprise, LLC (doing business as Emedical Sentry) aims to improve the detection and management of asthma attacks through remote patient monitoring. The goal is to enhance telehealth by incorporating video-based vital sign...
- The National Heart, Lung, and Blood Institute (NHLBI) awarded a $269,922 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to Steth X Microsystems Inc. to develop a smart, wearable contact microphone patch for extended and remote monitoring of lung functions. The goal is to create a low-profile, battery-powered wireless device capable of accurately detecting and quantifying adventitious lung sounds as well as breathing abnormalities in patients with respiratory...
NON-CONTACT IN-BED SENSING OF HEART FAILURE DECOMPENSATION - PROJECT ABSTRACT: CHRONIC HEART FAILURE IS A HIGHLY PREVALENT AND COSTLY DISEASE MARKED BY FREQUENT EXACERBATIONS LEADING TO RECURRENT HOSPITALIZATIONS. HEART FAILURE PATIENTS HAVE EXTRAORDINARILY HIGH HOSPITALIZATION RATES FOR FLUID OVERLOAD, WHICH CAN OFTEN BE AVOIDED IF EXACERBATIONS ARE DETECTED EARLY AND DIURETIC THERAPY IS INTENSIFIED IN THE OUTPATIENT SETTING. UNFORTUNATELY, SELF- MEASUREMENT OF WEIGHTS AND SELF-REPORTING OF SYMPTOMS HAVE PROVEN INEFFECTIVE. THE UTILITY OF HOME MONITORING TECHNOLOGIES HAS BEEN LIMITED BY POOR ADHERENCE TO SELF-MEASUREMENT, SELF- TRANSMISSION OF DATA, OR SELF-APPLICATION OF WEARABLES. IMPLANTABLE DEVICES HAVE SHOWN SUCCESS BUT ARE INVASIVE AND EXPENSIVE. NON-CONTACT SENSORS ARE CURRENTLY POSITION-DEPENDENT AND NOT COMPATIBLE WITH MULTIPLE PERSONS SLEEPING IN THE SAME BED. NIGHTINGALE LABS WAS FOUNDED TO COMMERCIALIZE A NON-CONTACT ADHERENCE-INDEPENDENT SENSOR CALLED BEDSCALES. OUR PRELIMINARY RESULTS SHOW THAT THE LOW-PROFILE MECHANICAL SENSORS, WHEN PLACED BENEATH THE LEGS OF A HOME BED, CAN PERFORM ADHERENCE-INDEPENDENT SENSING OF TOTAL BODY WEIGHT, MOVEMENTS, RESPIRATIONS, AND CARDIAC SIGNALS FOR MONTHS WITHOUT PATIENT INTERACTION, EVEN IF THE BED IS SHARED BY PARTNERS OR PETS. THE OVERALL GOAL OF THIS PHASE I SBIR IS TO DEFINE SENSOR ACCURACY IN A REAL- WORLD HEART FAILURE POPULATION IN PREPARATION FOR A PROSPECTIVE CLINICAL STUDY IN PHASE 2. BY DEFINING THE SIGNATURES OF IMPENDING HOSPITALIZATION, BEDSCALES AIMS TO MAKE OUTPATIENT MANAGEMENT OF HEART FAILURE A DATA-DRIVEN SCIENCE.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $0 | 12/7/23 | ||
| Not listed | $0 | 3/30/22 | ||
| Not listed | $0 | 3/30/22 | ||
| Not listed | $223.6k | 3/10/21 | ||
| Not listed | $223.6k | 3/10/21 |