Project Grant R43CA302403
- This federal Project Grant award from the National Center for Advancing Translational Sciences (NCATS) under CFDA 93.350 provides $406,500.00 to Syntr Health Technologies, Inc. to develop an automated, microfluidic tissue dissociation platform called the SYNTRFUGE. This device aims to rapidly and efficiently process solid tumor tissue samples into single cells for diagnostic analysis and research, addressing a critical barrier to more widespread use of single-cell analysis in oncology. The...
- The National Center for Advancing Translational Sciences (NCATS) awarded a $1,050,276 Project Grant to Syntr Health Technologies, Inc. on September 25, 2025 under the CFDA 93.350 Federal Grant Program. This funding supports the development and automation of an FDA-cleared CD-microfluidic platform for rapid tissue microsizing. The platform technology can process a variety of tissue types, including cancer tumors and adipose tissue, to enable single-cell analysis and regenerative medical...
- This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Cerflux Inc. aims to develop a personalized cancer treatment screening platform. The project will establish guidelines for handling solid tumor biopsy samples, generate 3D bioprinted tumor models for validation, and demonstrate the platform's ability to match patients with the most effective cancer treatments before treatment begins. This innovative approach has the...
- This $274,594 Project Grant award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program supports research and development of an innovative technology for cancer diagnosis and treatment. The project aims to improve molecular profiling and clinical laboratory testing of cancer samples by optimizing microdissection techniques. The research will focus on modeling and optimizing the opto-thermal-mechanical interactions involved in microdissection to...
- This Project Grant from the National Science Foundation's Technology, Innovation, and Partnerships program (CFDA 47.084) provides $275,000 to Dcan Biosciences LLC to develop an advanced microfluidic system for cancer diagnosis and monitoring. The system aims to isolate and assess circulating tumor cells (CTCs) and CTC clusters (CTCCs) from patient blood samples to enable highly sensitive and accurate liquid biopsies. Key objectives include designing a hybrid microfluidic device for...
- The federal Project Grant award of $247,660 from the National Cancer Institute (CFDA 93.395 - Cancer Treatment Research) is supporting research to characterize the microenvironment of autologous fat grafts resulting from different intraoperative processing techniques. This study aims to compare outcomes, including volume retention, between three fat grafting devices that process the lipoaspirate in different ways before injection. The project will utilize fat samples collected from patients...
- This Project Grant award, valued at $305,000.00 and provided by the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program, supports the development and commercialization of a novel light-activatable nanoplatform for the targeted delivery of photodynamic therapy (PDT) and chemotherapy to treat peritoneal metastasis. The nanoplatform is designed to selectively eliminate cancer cells that could not be removed by surgery, with the goal of...
- This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $305,000 to Bullseye Biodevices, Inc. aims to develop a novel biosensing device for rapidly mapping volumetric tumor margins during surgical interventions for cancer. The key product under development is an electromechanical probe and sensor system that can generate real-time, 3D maps of tumor location and boundaries by measuring biophysical properties like force, deformation, and...
- This federal Project Grant award of $374,095 from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), aims to develop a device that uses an infrared laser to enable local delivery of a high dose of chemotherapy to the surgical cavity after tumor resection. The technology employs thermosensitive liposomal nanoparticles encapsulating chemotherapy agents that...
- This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Phase I Small Business Innovation Research (SBIR) grant for $305,000 awarded to Redpoint Oncology, Inc. aims to develop and validate a novel platform for targeted cancer therapies. The project seeks to create new cancer treatments designed to target and destroy cancer cells for a broad range of different cancers. The project's broader impact includes addressing critical unmet medical needs and...
This federal Project Grant award from the National Cancer Institute (CFDA 93.395 - Cancer Treatment Research) provides $356,500.00 to Syntr Health Technologies, Inc. to accelerate the development of their SYNTRFUGE and SYNTRFPU360 tissue processing platform technology. This platform aims to enable large-volume tissue processing, including for tumor tissue analysis and adipose tissue for breast cancer reconstructive surgery and other regenerative medicine applications. The funds will support the seamless integration and scaling of this technology, which has the potential to disrupt several medical markets including oncology, wound healing, and orthopedics. Preliminary animal and human clinical data has demonstrated the ability of Syntr's technology to process and microsize adipose tissue for the treatment of diabetic foot ulcers. The overarching goal is to advance bioengineering solutions that can increase access to innovative treatments targeting breast cancer reconstruction and other critical medical needs.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $356.5k | 8/29/25 |