Project Grant R41AG091992
- The National Institute on Aging (NIA), under the Federal Aging Research program (CFDA 93.866), awarded a $245,148 project grant to Eyenexo LLC to develop an automated rodent behavior testing system for non-invasively assessing early-stage Alzheimer's disease (AD). The project aims to develop a behavior biomarker that can differentiate AD from normal aging by studying defensive behaviors triggered by looming stimuli, which are linked to early AD pathology in the midbrain region. The 2-year...
- This Project Grant award from the National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), aims to investigate the presence of Alzheimer's disease (AD) biomarkers in nasally exhaled breath. The $440,000 award to Northwestern University will fund research to test the hypothesis that neural proteins associated with AD, such as tau and beta-amyloid, can be detected and quantified in nasally exhaled breath samples. The 2-year project period runs from...
- The National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), awarded a $320,511 project grant to TRU Diagnostics Inc. to develop a novel diagnostic tool for chronic diseases. The project aims to create a "non-stochastic W function epigenomic roadmap" using systems-based dynamic modeling to capture the shifting homeostatic set points of epigenetic markers over time. This transformative approach aims to enable personalized, dynamic health forecasts...
- The National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), awarded $266,174 to the Monell Chemical Senses Center on September 20, 2025 for the "Monell Scientist Entrepreneurial Program for Healthy Aging (MSEP-HA)". This project grant aims to train graduate students and postdoctoral researchers in commercializing innovations related to smell loss, which is an early biomarker of neurodegenerative diseases like Alzheimer's. The 3-week program will...
- The National Institute on Aging (NIA), through its Aging Research Federal Grant Program (CFDA 93.866), awarded a $499,778 project grant to S-3 Research LLC to co-design a mobile tool to improve diversity and inclusivity in Alzheimer's Disease and Related Dementias (ADRD) clinical trial participation. The project aims to leverage digital approaches, including mobile, website, and artificial intelligence chatbot features, to enhance the education, recruitment, and enrollment of older adults in...
- This Project Grant award of $446,619, provided by the National Institute on Aging (NIA) under CFDA 93.866 "Aging Research", will support a research project titled "NOVEL OLFACTORY-BASED APPROACH TO MEASURE RISKS OF ALZHEIMER'S DISEASE AND RELATED DEMENTIAS IN DIVERSE POPULATIONS". The project aims to rigorously evaluate an olfactory-based approach for measuring memory function and adapt the protocol to facilitate its inclusion in population-based surveys globally. Key...
- The National Institute on Aging (NIA), part of the Department of Health and Human Services National Institutes of Health, awarded a $3.37 million Project Grant to The University of Texas at Arlington to develop an individualized deep connectome framework for Alzheimer's disease and related dementias (ADRD) analysis. The three-year grant, awarded on August 18, 2022 under the NIA's Aging Research program (CFDA 93.866), will support research to discover and identify individualized...
- The National Institute on Aging (NIA), part of the U.S. Department of Health and Human Services, awarded a $1,249,957 Project Grant under CFDA 93.866 (Aging Research) to Advantage Therapeutics, Inc. in Florida. The grant aims to perform IND-enabling studies on a small molecule that is disease-modifying, low-cost, and has a long safety record for the treatment of Alzheimer's disease. The proposed molecule is designed to reduce brain inflammation and restore phagocytosis, thereby improving the...
- The National Institute on Aging (NIA) awarded a $483,346 Project Grant to Meganano Diagnostics Inc. under the Aging Research Federal Grant Program (CFDA 93.866) for the development of an RT-qPCR assay for early diagnosis of Alzheimer's disease (AD). The project aims to leverage changes in T cell receptor (TCR) clonality in peripheral blood mononuclear cells (PBMCs) as a potential biomarker for early AD detection. Preliminary research by Meganano Diagnostics has demonstrated increased TCR...
- The National Institute on Aging (NIA), part of the U.S. Department of Health and Human Services, awarded a $474,092 Project Grant under the Aging Research federal grant program (CFDA 93.866) to One Health Studio LLC in San Francisco, CA. The grant supports the development and evaluation of the "FLOURISH ALL" platform, an AI-enabled digital health solution aimed at reducing Alzheimer's disease and related dementia (ADRD) risk in midlife women through stress management and promotion of...
The National Institute on Aging (NIA), part of the U.S. Department of Health and Human Services, awarded a $493,964 Project Grant under the Aging Research federal grant program (CFDA 93.866) to Aromha Inc. on September 10, 2025. The grant will fund the development and evaluation of a digital, self-administered, multilingual olfactory test battery called the AROMHA Brain Health Test. The goal is to create an at-home screening tool to detect early signs of Lewy body disease, which is present in up to 60% of Alzheimer's disease cases. The project will tailor the AROMHA app and smell card system to identify odor identification, memory, and discrimination deficits that are early indicators of Lewy body pathology. This digital remote testing solution aims to enable more efficient recruitment and validated outcome measures for preclinical trials targeting Lewy body and Alzheimer's diseases. The project is expected to be completed by July 31, 2026.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $494.0k | 9/9/25 |