The federal Project Grant award R35HL177401, totaling $1,091,824.00, was awarded to Northwestern University on February 1, 2025 by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837). The research project, titled "Phagocyte Crosstalk in the Balance of Inflammation & Cardiac Disease," aims to investigate the underlying mechanisms and causal factors that contribute to chronic inflammation and its role in the pathophysiology of heart failure and acute ischemic injury. The study will leverage experimental animal models and human samples to identify key immunometabolic signaling pathways and communication between macrophages and cardiac progenitor cells, with the goal of developing new therapeutic strategies to resolve cardiac inflammation and promote tissue repair. This comprehensive research program seeks to advance the scientific understanding of the complex interplay between inflammation and cardiovascular disease, ultimately leading to improved treatments and outcomes for patients.
Generated 3/4/25, 8:27 AM