Project Grant R35GM160210
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $422,931.00 to the University of Colorado-Denver to characterize how specialized microbial metabolites mediate interactions within the human microbiome. The research aims to elucidate the role of these metabolites in enabling microbial communities to resist antimicrobial therapies, with the goal of improving...
- The National Institute of General Medical Sciences (NIGMS) awarded a $402,500 Project Grant under the Biomedical Research and Research Training (CFDA 93.859) federal grant program to the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University. The grant, which runs from January 1, 2025 to November 30, 2029, aims to develop synthetic biology tools and strategies to streamline the engineering of bacterial theragnostic systems that can sense and respond to specific disease...
- The Project Grant award, titled "Simplifying the Description, Not the System: Advanced Ecological Theory for Real-World Microbiomes", is funded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). Over the 5-year period from September 1, 2025 to August 31, 2030, the $326,550 grant will support research at The Washington University in University City, MO to develop computational tools and statistical...
- This federal Project Grant award for $353,500.00, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports research to investigate the impact of xenobiotic exposure on the gut microbiome and its resilience against gastrointestinal pathogens. The research program aims to fill a critical knowledge gap by examining how xenobiotics and their biotransformation products affect the composition, metabolism,...
- The federal Project Grant award of $420,066.00 from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) will fund research to systematically characterize how regulatory networks control secondary metabolism in microbes. The project aims to use genome-wide screens and multi-omics approaches to predict and access the unexplored biosynthetic potential of microbes, with the goal of accelerating the discovery,...
- This federal Project Grant award of $1,921,875.00 from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports research to map the nutritional landscape and determine how it impacts microbial community assembly, spatial organization, and interactions within host-associated microbial communities. The research aims to use chronic wounds as a model system to gain an unprecedented view of microbes in their...
- The National Institute of General Medical Sciences (NIGMS) awarded a $557,900 Project Grant to the Massachusetts Institute of Technology (MIT) under the Biomedical Research and Research Training program (CFDA 93.859). The grant funds a long-term research strategy to study ongoing adaptation and selective forces within human microbiomes. Using a culture-dependent genomic approach, the project aims to characterize within-person evolution over a dozen microbial species found in the skin, vagina,...
- This $421,250 Project Grant awarded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) will support research to elucidate how lifestyle factors such as diet, exercise, and social interactions shape the gut microbiome's contributions to human metabolic health. Over the 5-year grant period from September 2025 to June 2030, the research will be conducted by the President and Fellows of Harvard College. The...
- This Project Grant award, valued at $451,000.00 and funded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports research to determine the physiological nutrients and metabolic pathways required for fibroblast extracellular matrix (ECM) synthesis during tissue repair. The research program, to be conducted at the University of Chicago from September 1, 2025 to August 31, 2030, aims to address the central...
- This Project Grant award for $2,158,750.00, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports research at Rutgers, The State University of New Jersey to investigate how the host metabolism impacts immune responses during bacterial infections. The research aims to deepen the mechanistic understanding of how host metabolic activities influence immune cell activation and function, with a focus...
This Project Grant award, valued at $442,750.00 and funded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports research to advance the fundamental understanding of how host-derived metabolites, specifically nitrate, shape the ecology of host-associated microbial communities and their impacts on host health. The award, effective August 15, 2025 through April 30, 2030, will be performed by the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, a prominent academic medical institution with extensive experience in conducting advanced medical research and providing specialized scientific services to federal agencies. The research aims to decipher the complex interactions between nitrate-utilizing symbionts, co-residing pathobionts, and the host at nitrate-rich barrier sites, with the goal of unlocking the therapeutic potential of manipulating the microbial balance to promote human health.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $442.8k | 8/6/25 |