This Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training (CFDA 93.859) program, provides $373,117 to Emory University to develop novel bowl-shaped catalysts for selective C-H functionalization. The project aims to transform pharmaceutical drug synthesis by enabling access to chiral scaffolds and improving site-selectivity in C-H bond activation, which has potential applications in drug discovery and large-scale process chemistry. Over the 5-year award period from August 2025 to May 2030, the research will evaluate four series of bowl-shaped catalysts and optimize the systems to operate under low catalyst loadings. The project builds on Emory University's expertise in advanced biomedical research and established track record of securing federal grants from agencies like the NIH.
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