This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), part of the Biomedical Research and Research Training (CFDA 93.859) program, will support research to investigate dynamic pattern formation in the cell cortex. The $414,285 award to the University of Wisconsin System will fund a 5-year project focused on understanding the self-organizing patterns of Rho GTPase activity that direct critical cellular processes such as cell division, morphogenesis, and damage repair. The research aims to elucidate the rules governing the formation of these dynamic cortical patterns and their links to diverse biological functions. This work will provide fundamental insights into the mechanisms underlying proper cell behavior and the pathologies that arise when cortical reorganization is impaired.
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